KLIFS: a structural kinase-ligand interaction database

Analyzing Multitarget Activity Landscapes Using Protein–Ligand Interaction Fingerprints: Interaction Cliffs

(2015) Oscar Méndez-Lucio et al.   Journal of Chemical Information and Modeling

ChEMBL web services: streamlining access to drug discovery data and utilities

(2015) Mark Davies et al.   NUCLEIC ACIDS RESEARCH

Exploration of Type II Binding Mode: A Privileged Approach for Kinase Inhibitor Focused Drug Discovery?

(2014) Zheng Zhao et al.   ACS Chemical Biology

The chemical component dictionary: complete descriptions of constituent molecules in experimentally determined 3D macromolecules in the Protein Data Bank

(2014) John D. Westbrook et al.   BIOINFORMATICS

Purine derivatives as potent Bruton’s tyrosine kinase (BTK) inhibitors for autoimmune diseases

(2014) Qing Shi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

iview: an interactive WebGL visualizer for protein-ligand complex

(2014) Hongjian Li et al.   BMC BIOINFORMATICS

Kinases as Druggable Targets in Trypanosomatid Protozoan Parasites

(2014) Christopher Merritt et al.   CHEMICAL REVIEWS

Current Compound Coverage of the Kinome

(2014) Ye Hu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Comprehensive Analysis of Three-Dimensional Activity Cliffs Formed by Kinase Inhibitors with Different Binding Modes and Cliff Mapping of Structural Analogues

(2014) Norbert Furtmann et al.   JOURNAL OF MEDICINAL CHEMISTRY

Genenames.org: the HGNC resources in 2015

(2014) Kristian A. Gray et al.   NUCLEIC ACIDS RESEARCH

sc-PDB: a 3D-database of ligandable binding sites—10 years on

(2014) Jérémy Desaphy et al.   NUCLEIC ACIDS RESEARCH

The RCSB Protein Data Bank: views of structural biology for basic and applied research and education

(2014) Peter W. Rose et al.   NUCLEIC ACIDS RESEARCH

Protoss: a holistic approach to predict tautomers and protonation states in protein-ligand complexes

(2014) Stefan Bietz et al.   Journal of Cheminformatics

KLIFS: A Knowledge-Based Structural Database To Navigate Kinase–Ligand Interaction Space

(2013) Oscar P. J. van Linden et al.   JOURNAL OF MEDICINAL CHEMISTRY

Ambit-Tautomer: An Open Source Tool for Tautomer Generation

(2013) Nikolay T. Kochev et al.   Molecular Informatics

A conserved water-mediated hydrogen bond network defines bosutinib's kinase selectivity

(2013) Nicholas M Levinson et al.   Nature Chemical Biology

Activities at the Universal Protein Resource (UniProt)

(2013)   NUCLEIC ACIDS RESEARCH

PDBe: Protein Data Bank in Europe

(2013) Aleksandras Gutmanas et al.   NUCLEIC ACIDS RESEARCH

Kinome Render: a stand-alone and web-accessible tool to annotate the human protein kinome tree

(2013) Matthieu Chartier et al.   PeerJ

New Directions in Targeting Protein Kinases: Focusing Upon True Allosteric and Bivalent Inhibitors

(2012) Vandana Lamba et al.   CURRENT PHARMACEUTICAL DESIGN

Small and colorful stones make beautiful mosaics: fragment-based chemogenomics

(2012) Chris de Graaf et al.   DRUG DISCOVERY TODAY

KIDFamMap: a database of kinase-inhibitor-disease family maps for kinase inhibitor selectivity and binding mechanisms

(2012) Yi-Yuan Chiu et al.   NUCLEIC ACIDS RESEARCH

Visualisation of the chemical space of fragments, lead-like and drug-like molecules in PubChem

(2011) Ruud van Deursen et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Extended-Connectivity Fingerprints

(2010) David Rogers et al.   Journal of Chemical Information and Modeling

Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases

(2008) Beth Apsel et al.   Nature Chemical Biology