Dicer interacts with SIRT7 and regulates H3K18 deacetylation in response to DNA damaging agents

Sirtuin 7 promotes cellular survival following genomic stress by attenuation of DNA damage, SAPK activation and p53 response

(2015) Shashi Kiran et al.   EXPERIMENTAL CELL RESEARCH

Dicer Knockdown Inhibits Endothelial Cell Tumor Growth via MicroRNA 21a-3p Targeting of Nox-4

(2014) Gayle M. Gordillo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of microRNA biogenesis

(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Human nuclear Dicer restricts the deleterious accumulation of endogenous double-stranded RNA

(2014) Eleanor White et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Comparative interactomes of SIRT6 and SIRT7: Implication of functional links to aging

(2014) Namgyu Lee et al.   PROTEOMICS

Stochastic genome-nuclear lamina interactions

(2014) Jop Kind et al.   Nucleus

Closing the (nuclear) envelope on the genome: How nuclear lamins interact with promoters and modulate gene expression

(2013) Philippe Collas et al.   BIOESSAYS

Intracellular distribution of human SIRT7 and mapping of the nuclear/nucleolar localization signal

(2013) Shashi Kiran et al.   FEBS Journal

p63 is an alternative p53 repressor in melanoma that confers chemoresistance and a poor prognosis

(2013) Rubeta N. Matin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Repression of RNA Polymerase I upon Stress Is Caused by Inhibition of RNA-Dependent Deacetylation of PAF53 by SIRT7

(2013) Sifan Chen et al.   MOLECULAR CELL

A dosage-dependent pleiotropic role of Dicer in prostate cancer growth and metastasis

(2013) B Zhang et al.   ONCOGENE

SIRT7 Represses Myc Activity to Suppress ER Stress and Prevent Fatty Liver Disease

(2013) Jiyung Shin et al.   Cell Reports

Different means, same end—heterochromatin formation by RNAi and RNAi-independent RNA processing factors in fission yeast

(2012) Francisca E Reyes-Turcu et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin

(2012) M. Teta et al.   DEVELOPMENT

Functional Proteomics Establishes the Interaction of SIRT7 with Chromatin Remodeling Complexes and Expands Its Role in Regulation of RNA Polymerase I Transcription

(2012) Yuan-Chin Tsai et al.   MOLECULAR & CELLULAR PROTEOMICS

Regulation of human Dicer by the resident ER membrane protein CLIMP-63

(2012) Geneviève Pépin et al.   NUCLEIC ACIDS RESEARCH

miR-3928 activates ATR pathway by targeting Dicer

(2012) Lei Chang et al.   RNA Biology

In vivo structure-function analysis of human Dicer reveals directional processing of precursor miRNAs

(2012) A. M. Gurtan et al.   RNA

Normal DNA Methylation Dynamics in DICER1-Deficient Mouse Embryonic Stem Cells

(2012) Jonathan Ip et al.   PLoS Genetics

Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors

(2011) H Ogiwara et al.   ONCOGENE

Mammalian Sirtuins: Biological Insights and Disease Relevance

(2010) Marcia C. Haigis et al.   Annual Review of Pathology-Mechanisms of Disease

MicroRNA Biogenesis Is Required for Myc-Induced B-Cell Lymphoma Development and Survival

(2010) M. P. Arrate et al.   CANCER RESEARCH

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs

(2010) Xiaohua Su et al.   NATURE

Epigenetics: heterochromatin meets RNAi

(2009) Ingela Djupedal et al.   CELL RESEARCH

Disruption of Dicer1 Induces Dysregulated Fetal Gene Expression and Promotes Hepatocarcinogenesis

(2009) Shigeki Sekine et al.   GASTROENTEROLOGY

Dicer1 functions as a haploinsufficient tumor suppressor

(2009) M. S. Kumar et al.   GENES & DEVELOPMENT

Involvement of SIRT7 in resumption of rDNA transcription at the exit from mitosis

(2009) A. Grob et al.   JOURNAL OF CELL SCIENCE

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

Histones: Annotating Chromatin

(2008) Eric I. Campos et al.   Annual Review of Genetics

Sirt7 Increases Stress Resistance of Cardiomyocytes and Prevents Apoptosis and Inflammatory Cardiomyopathy in Mice

(2008) Olesya Vakhrusheva et al.   CIRCULATION RESEARCH

Decreased Dicer expression elicits DNA damage and up-regulation of MICA and MICB

(2008) Kai-Fu Tang et al.   JOURNAL OF CELL BIOLOGY

Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells

(2008) Rajini Mudhasani et al.   JOURNAL OF CELL BIOLOGY

MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells

(2008) Lasse Sinkkonen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases

(2008) Roberta Benetti et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs

(2008) M. Landthaler et al.   RNA