Ceramide Synthesis Is Modulated by the Sphingosine Analog FTY720 via a Mixture of Uncompetitive and Noncompetitive Inhibition in an Acyl-CoA Chain Length-de pend ent Manner

FTY720 Inhibits Ceramide Synthases and Up-regulates Dihydrosphingosine 1-Phosphate Formation in Human Lung Endothelial Cells

(2009) Evgeny V. Berdyshev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chiral Vinylphosphonate and Phosphonate Analogues of the Immunosuppressive Agent FTY720

(2009) Xuequan Lu et al.   JOURNAL OF ORGANIC CHEMISTRY

Cyclical and Dose-Dependent Responses of Adult Human Mature Oligodendrocytes to Fingolimod

(2008) Veronique E. Miron et al.   AMERICAN JOURNAL OF PATHOLOGY

Production and release of sphingosine 1-phosphate and the phosphorylated form of the immunomodulator FTY720

(2008) A KIHARA   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Effects of Phosphorylation of Immunomodulatory Agent FTY720 (Fingolimod) on Antiproliferative Activity against Breast and Colon Cancer Cells

(2008) Yasuo Nagaoka et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Spisulosine (ES-285) induces prostate tumor PC-3 and LNCaP cell death by de novo synthesis of ceramide and PKCζ activation

(2008) Ana M. Sánchez et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

FTY720 (fingolimod) for relapsing multiple sclerosis

(2008) Alejandro Horga et al.   Expert Review of Neurotherapeutics