Optimal function of the DNA repair enzyme TDP1 requires its phosphorylation by ATM and/or DNA-PK

Tyrosyl-DNA Phosphodiesterase as a Target for Anticancer Therapy

(2012) Thomas Dexheimer et al.   Anti-Cancer Agents in Medicinal Chemistry

In vitro complementation of Tdp1 deficiency indicates a stabilized enzyme-DNA adduct from tyrosyl but not glycolate lesions as a consequence of the SCAN1 mutation

(2009) Amy J. Hawkins et al.   DNA REPAIR

Tyrosyl-DNA phosphodiesterase and the repair of 3′-phosphoglycolate-terminated DNA double-strand breaks

(2009) Tong Zhou et al.   DNA REPAIR

Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks

(2009) Olivier Sordet et al.   EMBO REPORTS

Specific recognition of a multiply phosphorylated motif in the DNA repair scaffold XRCC1 by the FHA domain of human PNK

(2009) Ammar A. E. Ali et al.   NUCLEIC ACIDS RESEARCH

XRCC1 and DNA polymerase β in cellular protection against cytotoxic DNA single-strand breaks

(2008) Julie K Horton et al.   CELL RESEARCH

PI3K-Akt signaling regulates basal, but MAP-kinase signaling regulates radiation-induced XRCC1 expression in human tumor cells in vitro

(2008) M TOULANY et al.   DNA REPAIR

Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair

(2008) Wen-Cheng Chou et al.   EMBO JOURNAL

CHIP-Mediated Degradation and DNA Damage-Dependent Stabilization Regulate Base Excision Repair Proteins

(2008) Jason L. Parsons et al.   MOLECULAR CELL

Single-strand break repair and genetic disease

(2008) Keith W. Caldecott   NATURE REVIEWS GENETICS

ATR: an essential regulator of genome integrity

(2008) Karlene A. Cimprich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Histone H1 functions as a stimulatory factor in backup pathways of NHEJ

(2008) B. Rosidi et al.   NUCLEIC ACIDS RESEARCH