A Quantitative Assay Reveals Ligand Specificity of the DNA Scaffold Repair Protein XRCC1 and Efficient Disassembly of Complexes of XRCC1 and the Poly(ADP-ribose) Polymerase 1 by Poly(ADP-ribose) Glycohydrolase

Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease

(2013) Reza Sharifi et al.   EMBO JOURNAL

The FHA and BRCT domains recognize ADP-ribosylation during DNA damage response

(2013) M. Li et al.   GENES & DEVELOPMENT

Damage response of XRCC1 at sites of DNA single strand breaks is regulated by phosphorylation and ubiquitylation after degradation of poly(ADP-ribose)

(2013) L. Wei et al.   JOURNAL OF CELL SCIENCE

Therapeutic applications of PARP inhibitors: Anticancer therapy and beyond

(2013) Nicola J. Curtin et al.   MOLECULAR ASPECTS OF MEDICINE

Macrodomain-containing proteins: regulating new intracellular functions of mono(ADP-ribosyl)ation

(2013) Karla L. H. Feijs et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Large-scale preparation and characterization of poly(ADP-ribose) and defined length polymers

(2012) Edwin S. Tan et al.   ANALYTICAL BIOCHEMISTRY

Inhibition of poly(ADP-ribose) glycohydrolase (PARG) specifically kills BRCA2-deficient tumor cells

(2012) Catherine Fathers et al.   CELL CYCLE

Recognition of the iso-ADP-ribose moiety in poly(ADP-ribose) by WWE domains suggests a general mechanism for poly(ADP-ribosyl)ation-dependent ubiquitination

(2012) Z. Wang et al.   GENES & DEVELOPMENT

Structure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding element

(2012) In-Kwon Kim et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CHFR is important for the first wave of ubiquitination at DNA damage sites

(2012) Chao Liu et al.   NUCLEIC ACIDS RESEARCH

Quantitative proteomics profiling of the poly(ADP-ribose)-related response to genotoxic stress

(2012) Jean-Philippe Gagné et al.   NUCLEIC ACIDS RESEARCH

The structural basis for partitioning of the XRCC1/DNA ligase III-α BRCT-mediated dimer complexes

(2011) Matthew J. Cuneo et al.   NUCLEIC ACIDS RESEARCH

Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage

(2011) H. C. Kang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Poly(ADP-ribose) polymerase inhibitors as promising cancer therapeutics

(2010) Jin-xue He et al.   ACTA PHARMACOLOGICA SINICA

XRCC1 phosphorylation by CK2 is required for its stability and efficient DNA repair

(2010) Jason L. Parsons et al.   DNA REPAIR

The expanding field of poly(ADP-ribosyl)ation reactions. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series

(2008) Antoinette Hakmé et al.   EMBO REPORTS

Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins

(2008) Ivan Ahel et al.   NATURE

Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes

(2008) Jean-Philippe Gagné et al.   NUCLEIC ACIDS RESEARCH