Epigenomic targets for the treatment of respiratory disease

Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer

(2010) Dmitri Lodygin et al.   CELL CYCLE

Environmental Epigenetics and Asthma

(2008) Rachel L. Miller et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Thy-1 Promoter Hypermethylation

(2008) Yan Y. Sanders et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Epigenetics, DNA Methylation, and Chromatin Modifying Drugs

(2008) Moshe Szyf   Annual Review of Pharmacology and Toxicology

Deacetylases and NF-κB in Redox Regulation of Cigarette Smoke-Induced Lung Inflammation: Epigenetics in Pathogenesis of COPD

(2008) Saravanan Rajendrasozhan et al.   ANTIOXIDANTS & REDOX SIGNALING

DLEC1 and MLH1 promoter methylation are associated with poor prognosis in non-small cell lung carcinoma

(2008) T J Seng et al.   BRITISH JOURNAL OF CANCER

Expression of methylation-related genes is associated with overall survival in patients with non-small cell lung cancer

(2008) J Xing et al.   BRITISH JOURNAL OF CANCER

MicroRNA Signature Predicts Survival and Relapse in Lung Cancer

(2008) Sung-Liang Yu et al.   CANCER CELL

Promoter Methylation of Genes in and around the Candidate Lung Cancer Susceptibility Locus 6q23-25

(2008) M. Tessema et al.   CANCER RESEARCH

Carcinogen-Induced Gene Promoter Hypermethylation Is Mediated by DNMT1 and Causal for Transformation of Immortalized Bronchial Epithelial Cells

(2008) Leah A. Damiani et al.   CANCER RESEARCH

Targeted Knockout of BRG1 Potentiates Lung Cancer Development

(2008) S. Glaros et al.   CANCER RESEARCH

Aberrant promoter hypermethylation in serum DNA from patients with silicosis

(2008) Shigeki Umemura et al.   CARCINOGENESIS

Epigenetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung

(2008) Julien D.F. Licchesi et al.   CARCINOGENESIS

Asbestos exposure predicts cell cycle control gene promoter methylation in pleural mesothelioma

(2008) B. C. Christensen et al.   CARCINOGENESIS

A Phase I Biological Study of MG98, an Oligodeoxynucleotide Antisense to DNA Methyltransferase 1, in Patients with High-Risk Myelodysplasia and Acute Myeloid Leukemia

(2008) R. B. Klisovic et al.   CLINICAL CANCER RESEARCH

Loss of Histone H4K20 Trimethylation Occurs in Preneoplasia and Influences Prognosis of Non-Small Cell Lung Cancer

(2008) A. Van Den Broeck et al.   CLINICAL CANCER RESEARCH

Prognostic Value of Mature MicroRNA-21 and MicroRNA-205 Overexpression in Non-Small Cell Lung Cancer by Quantitative Real-Time RT-PCR

(2008) A. Markou et al.   CLINICAL CHEMISTRY

Molecular Targets and Targeted Therapies for Malignant Mesothelioma

(2008) Camilla Palumbo et al.   CURRENT MEDICINAL CHEMISTRY

Large genomic rearrangements and germline epimutations in Lynch syndrome

(2008) Annette Gylling et al.   INTERNATIONAL JOURNAL OF CANCER

Hypomethylation of retrotransposable elements correlates with genomic instability in non-small cell lung cancer

(2008) Alexandros Daskalos et al.   INTERNATIONAL JOURNAL OF CANCER

Early phase II trial of oral vorinostat in relapsed or refractory breast, colorectal, or non-small cell lung cancer

(2008) Johan Vansteenkiste et al.   INVESTIGATIONAL NEW DRUGS

Epigenetic mechanisms silence a disintegrin and metalloprotease 33 expression in bronchial epithelial cells

(2008) Youwen Yang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The role of histone deacetylases in asthma and allergic diseases

(2008) Pankaj Bhavsar et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

PI3K signaling of autophagy is required for starvation tolerance and virulenceof Cryptococcus neoformans

(2008) Guowu Hu et al.   JOURNAL OF CLINICAL INVESTIGATION

Recent Advances in the Treatment of Malignant Pleural Mesothelioma

(2008) Suresh S. Ramalingam et al.   Journal of Thoracic Oncology

Response to the Methylation Inhibitor Dihydro-5-azacytidine in Mesothelioma Is Not Associated with Methylation of p16INK4a: Results of Cancer and Leukemia Group B 159904

(2008) Robert A. Kratzke et al.   Journal of Thoracic Oncology

Frequent p16 inactivation by homozygous deletion or methylation is associated with a poor prognosis in Japanese patients with pleural mesothelioma

(2008) Naruyuki Kobayashi et al.   LUNG CANCER

Moving AHEAD with an international human epigenome project

(2008) et al.   NATURE

DNA Methylation Markers and Early Recurrence in Stage I Lung Cancer

(2008) Malcolm V. Brock et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inter-individual variation of DNA methylation and its implications for large-scale epigenome mapping

(2008) Christoph Bock et al.   NUCLEIC ACIDS RESEARCH

Unmasking of epigenetically silenced candidate tumor suppressor genes by removal of methyl-CpG-binding domain proteins

(2008) L Lopez-Serra et al.   ONCOGENE

Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban/industrial location

(2008) C. Yauk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A microRNA DNA methylation signature for human cancer metastasis

(2008) A. Lujambio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MLH1 promoter germline-methylation in selected probands of Chinese hereditary non-polyposis colorectal cancer families

(2008) Heng-Hua Zhou et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Regulation of Airway Mucin Gene Expression

(2007) Philip Thai et al.   Annual Review of Physiology