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Title
TDP-43-Mediated Neuron Loss In Vivo Requires RNA-Binding Activity
Authors
Keywords
Motor neurons, Drosophila melanogaster, Missense mutation, Toxicity, Spinal cord, Cytoplasmic staining, DAPI staining, Subcellular localization
Journal
PLoS One
Volume 5, Issue 8, Pages e12247
Publisher
Public Library of Science (PLoS)
Online
2010-08-19
DOI
10.1371/journal.pone.0012247
References
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Related references
Note: Only part of the references are listed.- TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration
- (2010) C. Lagier-Tourenne et al. HUMAN MOLECULAR GENETICS
- Cytoplasmic Mislocalization of TDP-43 Is Toxic to Neurons and Enhanced by a Mutation Associated with Familial Amyotrophic Lateral Sclerosis
- (2010) S. J. Barmada et al. JOURNAL OF NEUROSCIENCE
- Review: Transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration
- (2010) T. F. Gendron et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- A Drosophila model for TDP-43 proteinopathy
- (2010) Y. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration
- (2010) Hans Wils et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transgenic Rat Model of Neurodegeneration Caused by Mutation in the TDP Gene
- (2010) Hongxia Zhou et al. PLoS Genetics
- TDP-43 Redistribution is an Early Event in Sporadic Amyotrophic Lateral Sclerosis
- (2009) Maria Teresa Giordana et al. BRAIN PATHOLOGY
- Rethinking ALS: The FUS about TDP-43
- (2009) Clotilde Lagier-Tourenne et al. CELL
- Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6
- (2009) Fabienne C Fiesel et al. EMBO JOURNAL
- Depletion of TDP-43 affectsDrosophila motoneuronsterminal synapsis and locomotive behavior
- (2009) Fabian Feiguin et al. FEBS LETTERS
- Truncation and pathogenic mutations facilitate the formation of intracellular aggregates of TDP-43
- (2009) Takashi Nonaka et al. HUMAN MOLECULAR GENETICS
- Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo
- (2009) Edor Kabashi et al. HUMAN MOLECULAR GENETICS
- TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration
- (2009) I. Wegorzewska et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis
- (2009) T. J. Kwiatkowski et al. SCIENCE
- Structural determinants of the cellular localization and shuttling of TDP-43
- (2008) Y. M. Ayala et al. JOURNAL OF CELL SCIENCE
- TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
- (2008) Edor Kabashi et al. NATURE GENETICS
- TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2008) J. Sreedharan et al. SCIENCE
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