Ubiquilin Modifies TDP-43 Toxicity in a Drosophila Model of Amyotrophic Lateral Sclerosis (ALS)
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Title
Ubiquilin Modifies TDP-43 Toxicity in a Drosophila Model of Amyotrophic Lateral Sclerosis (ALS)
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 285, Issue 15, Pages 11068-11072
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2010-02-17
DOI
10.1074/jbc.c109.078527
References
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Note: Only part of the references are listed.- Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6
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- TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration
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- Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branching
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- Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
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- The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases
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- Abnormal phosphorylation of Ser409/410 of TDP-43 in FTLD-U and ALS
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- Mutations in String/CDC25 inhibit cell cycle re-entry and neurodegeneration in a Drosophila model of Ataxia telangiectasia
- (2008) S. A. Rimkus et al. GENES & DEVELOPMENT
- Potentiation of Amyotrophic Lateral Sclerosis (ALS)-associated TDP-43 Aggregation by the Proteasome-targeting Factor, Ubiquilin 1
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- TDP-43 is a culprit in human neurodegeneration, and not just an innocent bystander
- (2008) Gareth T. Banks et al. MAMMALIAN GENOME
- TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
- (2008) Edor Kabashi et al. NATURE GENETICS
- TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expression
- (2008) Y. M. Ayala et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2008) J. Sreedharan et al. SCIENCE
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