STAT3 represents a molecular switch possibly inducing astroglial instead of oligodendroglial differentiation of oligodendroglial progenitor cells in Theiler's murine encephalomyelitis

Transcriptomic Meta-Analysis of Multiple Sclerosis and Its Experimental Models

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Transcription Factors and Th17 Cell Development in Experimental Autoimmune Encephalomyelitis

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Glial Scar Borders Are Formed by Newly Proliferated, Elongated Astrocytes That Interact to Corral Inflammatory and Fibrotic Cells via STAT3-Dependent Mechanisms after Spinal Cord Injury

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Roles of T helper 17 cells and interleukin-17 in neuroautoimmune diseases with emphasis on multiple sclerosis and Guillain-Barré syndrome as well as their animal models

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Olig2/Plp-positive progenitor cells give rise to Bergmann glia in the cerebellum

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Matrix metalloproteinase-12 deficiency ameliorates the clinical course and demyelination in Theiler’s murine encephalomyelitis

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Highly Malignant Behavior of a Murine Oligodendrocyte Precursor Cell Line following Transplantation into the Demyelinated and Nondemyelinated Central Nervous System

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Neuroprotection of Interleukin-6 Against NMDA-induced Neurotoxicity is Mediated by JAK/STAT3, MAPK/ERK, and PI3K/AKT Signaling Pathways

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Periventricular Demyelination and Axonal Pathology Is Associated with Subependymal Virus Spread in a Murine Model for Multiple Sclerosis

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Properties and Fate of Oligodendrocyte Progenitor Cells in the Corpus Callosum, Motor Cortex, and Piriform Cortex of the Mouse

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Genomic Analysis of Reactive Astrogliosis

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Signal transducer and activator of transcription-3/suppressor of cytokine signaling-3 (STAT3/SOCS3) axis in myeloid cells regulates neuroinflammation

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MADGene: retrieval and processing of gene identifier lists for the analysis of heterogeneous microarray datasets

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Axonopathy Is Associated with Complex Axonal Transport Defects in a Model of Multiple Sclerosis

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Distinct Spatio-Temporal Extracellular Matrix Accumulation within Demyelinated Spinal Cord Lesions in Theiler's Murine Encephalomyelitis

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Age-dependent fate and lineage restriction of single NG2 cells

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Increased p75 neurotrophin receptor expression in the canine distemper virus model of multiple sclerosis identifies aldynoglial schwann cells that emerge in response to axonal damage

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Independent replication of STAT3 association with multiple sclerosis risk in a large German case–control sample

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NG2-glia as Multipotent Neural Stem Cells: Fact or Fantasy?

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Genome-wide Association Study in a High-Risk Isolate for Multiple Sclerosis Reveals Associated Variants in STAT3 Gene

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Conditional deletion of Stat3 promotes neurogenesis and inhibits astrogliogenesis in neural stem cells

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Theiler's murine encephalomyelitis virus preferentially infects immature stages of the murine oligodendrocyte precursor cell line BO-1 and blocks oligodendrocytic differentiation in vitro

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CNS-Resident Glial Progenitor/Stem Cells Produce Schwann Cells as well as Oligodendrocytes during Repair of CNS Demyelination

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Meteorin promotes the formation of GFAP-positive glia via activation of the Jak-STAT3 pathway

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Tyrosine phosphatases Shp1 and Shp2 have unique and opposing roles in oligodendrocyte development

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NG2 Glia Generate New Oligodendrocytes But Few Astrocytes in a Murine Experimental Autoimmune Encephalomyelitis Model of Demyelinating Disease

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STAT3 inhibitors attenuate interferon-γ-induced neurotoxicity and inflammatory molecule production by human astrocytes

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Astrocytes: biology and pathology

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Machine learning approach identifies new pathways associated with demyelination in a viral model of multiple sclerosis

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Transgenic Inhibition of Astroglial NF- B Improves Functional Outcome in Experimental Autoimmune Encephalomyelitis by Suppressing Chronic Central Nervous System Inflammation

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Early Postnatal Proteolipid Promoter-Expressing Progenitors Produce Multilineage Cells In Vivo

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Generation and characterization of a polyclonal antibody for the detection of Theiler's murine encephalomyelitis virus by light and electron microscopy

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Multiple Sclerosis: An Immune or Neurodegenerative Disorder?

(2008) Bruce D. Trapp et al.   Annual Review of Neuroscience

Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis

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In vitro characterization of a murine oligodendrocyte precursor cell line (BO-1) following spontaneous immortalization

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STAT3 is a Critical Regulator of Astrogliosis and Scar Formation after Spinal Cord Injury

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Progeny of Olig2-Expressing Progenitors in the Gray and White Matter of the Adult Mouse Cerebral Cortex

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Genetic fate mapping of Olig2 progenitors in the injured adult cerebral cortex reveals preferential differentiation into astrocytes

(2008) Kouko Tatsumi et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET

Signal Transducer and Activator of Transcription-3: A Molecular Hub for Signaling Pathways in Gliomas

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PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice

(2008) Leanne E Rivers et al.   NATURE NEUROSCIENCE

Remyelination in the CNS: from biology to therapy

(2008) Robin J. M. Franklin et al.   NATURE REVIEWS NEUROSCIENCE

Limited remyelination in Theiler's murine encephalomyelitis due to insufficient oligodendroglial differentiation of nerve/glial antigen 2 (NG2)-positive putative oligodendroglial progenitor cells

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CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure

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