Plasmin-Dependent Modulation of the Blood–Brain Barrier: A Major Consideration during tPA-Induced Thrombolysis?
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Plasmin-Dependent Modulation of the Blood–Brain Barrier: A Major Consideration during tPA-Induced Thrombolysis?
Authors
Keywords
-
Journal
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
Volume 34, Issue 8, Pages 1283-1296
Publisher
SAGE Publications
Online
2014-06-04
DOI
10.1038/jcbfm.2014.99
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Tissue-Type Plasminogen Activator Is a Regulator of Monocyte Diapedesis through the Brain Endothelial Barrier
- (2014) A. Reijerkerk et al. JOURNAL OF IMMUNOLOGY
- Tissue-type plasminogen activator is not necessary for platelet-derived growth factor-c activation
- (2013) Kimberly J. Riehle et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Prevention of rt-PA induced blood–brain barrier component degradation by the poly(ADP-ribose)polymerase inhibitor PJ34 after ischemic stroke in mice
- (2013) Fei Teng et al. EXPERIMENTAL NEUROLOGY
- Ablation of astrocytic laminin impairs vascular smooth muscle cell function and leads to hemorrhagic stroke
- (2013) Zu-Lin Chen et al. JOURNAL OF CELL BIOLOGY
- Progesterone Attenuates Hemorrhagic Transformation after Delayed tPA Treatment in an Experimental Model of Stroke in Rats: Involvement of the VEGF–MMP Pathway
- (2013) Soonmi Won et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Hemostasis and Alterations of the Central Nervous System
- (2013) Yoshikane Izawa et al. SEMINARS IN THROMBOSIS AND HEMOSTASIS
- Plasminogen Receptors: The First Quarter Century
- (2013) Robert Parmer et al. SEMINARS IN THROMBOSIS AND HEMOSTASIS
- Optical imaging to map blood-brain barrier leakage
- (2013) Hayder Jaffer et al. Scientific Reports
- t-PA-specific modulation of a human blood-brain barrier model involves plasmin-mediated activation of the Rho kinase pathway in astrocytes
- (2012) B. Niego et al. BLOOD
- The tissue-type plasminogen activator–plasminogen activator inhibitor 1 complex promotes neurovascular injury in brain trauma: evidence from mice and humans
- (2012) Maithili Sashindranath et al. BRAIN
- Free Radical Scavenger Edaravone Administration Protects against Tissue Plasminogen Activator Induced Oxidative Stress and Blood Brain Barrier Damage
- (2012) Violeta Lukic-Panin et al. CURRENT NEUROVASCULAR RESEARCH
- Pharmacokinetics of alteplase in the treatment of ischaemic stroke
- (2012) Paul Acheampong et al. Expert Opinion on Drug Metabolism & Toxicology
- Plasmin as a proinflammatory cell activator
- (2012) T. Syrovets et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Spatiotemporal evolution of blood brain barrier damage and tissue infarction within the first 3h after ischemia onset
- (2012) Xinchun Jin et al. NEUROBIOLOGY OF DISEASE
- Combined tissue plasminogen activator and an NK1 tachykinin receptor antagonist: An effective treatment for reperfusion injury following acute ischemic stroke in rats
- (2012) R.J. Turner et al. NEUROSCIENCE
- A Rho kinase (ROCK) inhibitor, fasudil, prevents matrix metalloproteinase-9-related hemorrhagic transformation in mice treated with tissue plasminogen activator
- (2012) M. Ishiguro et al. NEUROSCIENCE
- Matrix metalloproteinase-2 or -9 deletions protect against hemorrhagic transformation during early stage of cerebral ischemia and reperfusion
- (2012) Y. Suofu et al. NEUROSCIENCE
- Nucleocytoplasmic Coagulation: An Injury-Induced Aggregation Event that Disulfide Crosslinks Proteins and Facilitates Their Removal by Plasmin
- (2012) Andre L. Samson et al. Cell Reports
- Truncation of monocyte chemoattractant protein 1 by plasmin promotes blood-brain barrier disruption
- (2011) Y. Yao et al. JOURNAL OF CELL SCIENCE
- Impact of Tissue Plasminogen Activator on the Neurovascular Unit: From Clinical Data to Experimental Evidence
- (2011) Denis Vivien et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Annexin A2 Promotes Glioma Cell Invasion and Tumor Progression
- (2011) H. Zhai et al. JOURNAL OF NEUROSCIENCE
- Compartment- and context-specific changes in tissue-type plasminogen activator (tPA) activity following brain injury and pharmacological stimulation
- (2011) Maithili Sashindranath et al. LABORATORY INVESTIGATION
- tPA contributes to impaired NMDA cerebrovasodilation after traumatic brain injury through activation of JNK MAPK
- (2011) William M Armstead et al. NEUROLOGICAL RESEARCH
- Structure, function and pathophysiology of protease activated receptors
- (2011) Mark N. Adams et al. PHARMACOLOGY & THERAPEUTICS
- Plasmin on adherent cells: from microvesiculation to apoptosis
- (2010) Loïc Doeuvre et al. BIOCHEMICAL JOURNAL
- Localization of plasminogen in mouse hippocampus, cerebral cortex, and hypothalamus
- (2010) Yuki Taniguchi et al. CELL AND TISSUE RESEARCH
- The plasmin–antiplasmin system: structural and functional aspects
- (2010) Johann Schaller et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The C Terminus of Mouse Monocyte Chemoattractant Protein 1 (MCP1) Mediates MCP1 Dimerization while Blocking Its Chemotactic Potency
- (2010) Yao Yao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials
- (2010) Kennedy R Lees et al. LANCET
- Molecular insights and therapeutic targets for blood–brain barrier disruption in ischemic stroke: Critical role of matrix metalloproteinases and tissue-type plasminogen activator
- (2010) Rong Jin et al. NEUROBIOLOGY OF DISEASE
- Blood–brain barrier permeability and tPA-mediated neurotoxicity
- (2010) Rami Abu Fanne et al. NEUROPHARMACOLOGY
- Increasing tPA Activity in Astrocytes Induced by Multipotent Mesenchymal Stromal Cells Facilitate Neurite Outgrowth after Stroke in the Mouse
- (2010) Hongqi Xin et al. PLoS One
- Phosphodiesterase-III Inhibitor Prevents Hemorrhagic Transformation Induced by Focal Cerebral Ischemia in Mice Treated with tPA
- (2010) Mitsunori Ishiguro et al. PLoS One
- Different therapy options protecting microvasculature after experimental cerebral ischaemia and reperfusion
- (2010) Dorothe Burggraf et al. THROMBOSIS AND HAEMOSTASIS
- Recombinant Tissue Plasminogen Activator Increases Blood-Brain Barrier Disruption in Acute Ischemic Stroke: An MR Imaging Permeability Study
- (2009) A. Kassner et al. AMERICAN JOURNAL OF NEURORADIOLOGY
- A nonfibrin macromolecular cofactor for tPA-mediated plasmin generation following cellular injury
- (2009) A. L. Samson et al. BLOOD
- Tissue-type plasminogen activator (t-PA) induces stromelysin-1 (MMP-3) in endothelial cells through activation of lipoprotein receptor-related protein
- (2009) Y. Suzuki et al. BLOOD
- Age and albumin D site-binding protein control tissue plasminogen activator levels: neurotoxic impact
- (2009) Benoit D. Roussel et al. BRAIN
- Characteristic response of astrocytes to plasminogen/plasmin to upregulate transforming growth factor beta 3 (TGFβ3) production/secretion through proteinase-activated receptor-1 (PAR-1) and the downstream phosphatidylinositol 3-kinase (PI3K)-Akt/PKB signaling cascade
- (2009) Shyuichi Maeda et al. BRAIN RESEARCH
- Microglial Low-Density Lipoprotein Receptor-Related Protein 1 Mediates the Effect of Tissue-Type Plasminogen Activator on Matrix Metalloproteinase-9 Activity in the Ischemic Brain
- (2009) Chen Zhang et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Dissociation and Protection of the Neurovascular Unit after Thrombolysis and Reperfusion in Ischemic Rat Brain
- (2009) Toru Yamashita et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- JNK-Induced MCP-1 Production in Spinal Cord Astrocytes Contributes to Central Sensitization and Neuropathic Pain
- (2009) Y.-J. Gao et al. JOURNAL OF NEUROSCIENCE
- Direct fibrinolytic agents: biochemical attributes, preclinical foundation and clinical potential
- (2009) V. J. MARDER et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Thrombolytic Toxicity: Blood Brain Barrier Disruption in Human Ischemic Stroke
- (2008) Chelsea S. Kidwell et al. CEREBROVASCULAR DISEASES
- Plasmin Potentiates SynapticN-Methyl-D-aspartate Receptor Function in Hippocampal Neurons through Activation of Protease-activated Receptor-1
- (2008) Guido Mannaioni et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Intracerebral haemorrhage after thrombolysis for acute ischaemic stroke: an update
- (2008) L Derex et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Low molecular weight contaminants in commercial preparations of plasmin and t-PA activate neurons
- (2008) A. L. SAMSON et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke
- (2008) Enming J Su et al. NATURE MEDICINE
- Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke
- (2008) Werner Hacke et al. NEW ENGLAND JOURNAL OF MEDICINE
- Edaravone, a Free Radical Scavenger, Inhibits MMP-9–Related Brain Hemorrhage in Rats Treated With Tissue Plasminogen Activator
- (2008) Kenji Yagi et al. STROKE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now