Progesterone Attenuates Hemorrhagic Transformation after Delayed tPA Treatment in an Experimental Model of Stroke in Rats: Involvement of the VEGF–MMP Pathway

Progesterone attenuates early brain injury after subarachnoid hemorrhage in rats

(2013) Feng Yan et al.   NEUROSCIENCE LETTERS

Breaking down barriers to identify hemorrhagic transformation in ischemic stroke

(2012) G. C. Jickling et al.   NEUROLOGY

A broad-spectrum matrix metalloproteinase inhibitor prevents hemorrhagic complications induced by tissue plasminogen activator in mice

(2012) K. Mishiro et al.   NEUROSCIENCE

Progesterone is neuroprotective against ischemic brain injury through its effects on the phosphoinositide 3-kinase/protein kinase B signaling pathway

(2012) T. Ishrat et al.   NEUROSCIENCE

Inhibition of VEGF signaling pathway attenuates hemorrhage after tPA treatment

(2011) Masato Kanazawa et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

How to make better use of thrombolytic therapy in acute ischemic stroke

(2011) Geoffrey A. Donnan et al.   Nature Reviews Neurology

Permeability of Endothelial and Astrocyte Cocultures: In Vitro Blood–Brain Barrier Models for Drug Delivery Studies

(2010) Guanglei Li et al.   ANNALS OF BIOMEDICAL ENGINEERING

Progesterone and allopregnanolone attenuate blood–brain barrier dysfunction following permanent focal ischemia by regulating the expression of matrix metalloproteinases

(2010) Tauheed Ishrat et al.   EXPERIMENTAL NEUROLOGY

Annexin A2 Combined with Low-Dose tPA Improves Thrombolytic Therapy in a Rat Model of Focal Embolic Stroke

(2010) Haihao Zhu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Phosphodiesterase-III Inhibitor Prevents Hemorrhagic Transformation Induced by Focal Cerebral Ischemia in Mice Treated with tPA

(2010) Mitsunori Ishiguro et al.   PLoS One

Cholesterol efflux stimulates metalloproteinase-mediated cleavage of occludin and release of extracellular membrane particles containing its C-terminal fragments

(2009) Elizabeth Casas et al.   EXPERIMENTAL CELL RESEARCH

Normobaric Hyperoxia Reduces the Neurovascular Complications Associated With Delayed Tissue Plasminogen Activator Treatment in a Rat Model of Focal Cerebral Ischemia

(2009) Wenlan Liu et al.   STROKE

Effects of progesterone administration on infarct volume and functional deficits following permanent focal cerebral ischemia in rats

(2008) Tauheed Ishrat et al.   BRAIN RESEARCH

Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke

(2008) Enming J Su et al.   NATURE MEDICINE

Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke

(2008) Werner Hacke et al.   NEW ENGLAND JOURNAL OF MEDICINE

Does Progesterone Have Neuroprotective Properties?

(2007) Donald G. Stein et al.   ANNALS OF EMERGENCY MEDICINE