Direct fibrinolytic agents: biochemical attributes, preclinical foundation and clinical potential

A pilot trial of microplasmin in patients with long-term venous access catheter thrombosis

(2009) Peter Verhamme et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Locally Applied Recombinant Plasmin Results in Effective Thrombolysis in a Porcine Model of Arteriovenous Graft Thrombosis

(2009) Imo E. Hoefer et al.   JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY

IV vs. IA TPA in Acute Ischemic Stroke with CT Angiographic Evidence of Major Vessel Occlusion: A Feasibility Study

(2009) Souvik Sen et al.   Neurocritical Care

Microplasmin Intravitreal Administration in Patients with Vitreomacular Traction Scheduled for Vitrectomy

(2009) Marc D. de Smet et al.   OPHTHALMOLOGY

Randomized, Placebo-Controlled, Dose-Ranging Clinical Trial of Intravenous Microplasmin in Patients With Acute Ischemic Stroke

(2009) Vincent N.S. Thijs et al.   STROKE

Targeting Extracellular Matrix Proteolysis for Hemorrhagic Complications of tPA Stroke Therapy

(2008) Xiaoying Wang et al.   CNS & Neurological Disorders-Drug Targets

A first-in-human phase I trial of locally delivered human plasmin for hemodialysis graft occlusion

(2008) R. D. SHLANSKY-GOLDBERG et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Effects of microplasmin on recovery in a rat embolic stroke model

(2008) Rune Skovgaard Rasmussen et al.   NEUROLOGICAL RESEARCH

Middle Cerebral Artery Occlusion in the Rabbit Using Selective Angiography

(2008) Reza Jahan et al.   STROKE

The thrombolytic effect of miniplasmin in a canine model of femoral artery thrombosis

(2008) Jieying Fu et al.   THROMBOSIS RESEARCH

Development of catheter-directed intrathrombus thrombolysis with plasmin for the treatment of acute lower extremity arterial occlusion

(2008) Anthony J. Comerota   THROMBOSIS RESEARCH

Structure and activity of plasmin and other direct thrombolytic agents

(2008) Valery Novokhatny   THROMBOSIS RESEARCH

Pre-clinical studies of plasmin: Superior benefit-to-risk ratio of plasmin compared to tissue plasminogen activator

(2008) Victor J. Marder   THROMBOSIS RESEARCH

Tissue-type plasminogen activator in the ischemic brain: more than a thrombolytic

(2008) Manuel Yepes et al.   TRENDS IN NEUROSCIENCES

Alfimeprase

(2008) &NA;   Drugs in research & development