Mouse Models to Study the Effect of Cardiovascular Risk Factors on Brain Structure and Cognition

Cerebral Blood Flow Measurement by PET in Hypertensive Subjects as a Marker of Cognitive Decline

(2017) Kazuo Kitagawa   JOURNAL OF ALZHEIMERS DISEASE

The global prevalence of dementia: A systematic review and metaanalysis

(2013) Martin Prince et al.   Alzheimers & Dementia

Link Between Change in Cognition and Left Ventricular Function Following Cardiac Resynchronization Therapy

(2013) Karin F. Hoth et al.   Journal of Cardiopulmonary Rehabilitation and Prevention

Effects of carotid artery stenting on cognitive function in patients with mild cognitive impairment and carotid stenosis

(2013) YONG CHENG et al.   Experimental and Therapeutic Medicine

Atherosclerotic calcification relates to cognitive function and to brain changes on magnetic resonance imaging

(2012) Daniel Bos et al.   Alzheimers & Dementia

Brain-Derived Neurotrophic Factor Protects Against Cardiac Dysfunction After Myocardial Infarction via a Central Nervous System–Mediated Pathway

(2012) Sho Okada et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Proximal Cerebral Arteries Develop Myogenic Responsiveness in Heart Failure via Tumor Necrosis Factor-α–Dependent Activation of Sphingosine-1-Phosphate Signaling

(2012) Jingli Yang et al.   CIRCULATION

Protective Effect of Carnosine on Subcortical Ischemic Vascular Dementia in Mice

(2012) Jing Ma et al.   CNS Neuroscience & Therapeutics

Hypertension Induces Brain β-Amyloid Accumulation, Cognitive Impairment, and Memory Deterioration Through Activation of Receptor for Advanced Glycation End Products in Brain Vasculature

(2012) Daniela Carnevale et al.   HYPERTENSION

Two-Photon Microscopy as a Tool to Study Blood Flow and Neurovascular Coupling in the Rodent Brain

(2012) Andy Y Shih et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease

(2012) Rashid Deane et al.   JOURNAL OF CLINICAL INVESTIGATION

Increase of arginase activity in old apolipoprotein-E deficient mice under Western diet associated with changes in neurovascular unit

(2012) Jérôme Badaut et al.   Journal of Neuroinflammation

Synaptic circuit remodelling by matrix metalloproteinases in health and disease

(2012) George W. Huntley   NATURE REVIEWS NEUROSCIENCE

Effects of mild chronic cerebral hypoperfusion and early amyloid pathology on spatial learning and the cellular innate immune response in mice

(2012) Pedro M. Pimentel-Coelho et al.   NEUROBIOLOGY OF AGING

The capillary dysfunction hypothesis of Alzheimer's disease

(2012) Leif Østergaard et al.   NEUROBIOLOGY OF AGING

Brain perfusion SPECT in the mouse: Normal pattern according to gender and age

(2012) Ivayla Apostolova et al.   NEUROIMAGE

Apolipoprotein E Sets the Stage: Response to Injury Triggers Neuropathology

(2012) Robert W. Mahley et al.   NEURON

Exercise protects against high-fat diet-induced hypothalamic inflammation

(2012) Chun-Xia Yi et al.   PHYSIOLOGY & BEHAVIOR

Sodium sulfide prevents water diffusion abnormality in the brain and improves long term outcome after cardiac arrest in mice

(2012) Kotaro Kida et al.   RESUSCITATION

Carotid Atherosclerosis and Prospective Risk of Dementia

(2012) Carrington R. Wendell et al.   STROKE

Heart Rate Variability Predicts Cell Death and Inflammatory Responses to Global Cerebral Ischemia

(2012) Greg J. Norman et al.   Frontiers in Physiology

Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical microinfarcts

(2011) Yoko Okamoto et al.   ACTA NEUROPATHOLOGICA

Heart rate-associated mechanical stress impairs carotid but not cerebral artery compliance in dyslipidemic atherosclerotic mice

(2011) Virginie Bolduc et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Chronic renal failure alters endothelial function in cerebral circulation in mice

(2011) Jean-Marc Bugnicourt et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Notch3 Arg170Cys Knock-In Mice Display Pathologic and Clinical Features of the Neurovascular Disorder Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy

(2011) Goedele Wallays et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Brain inflammation is induced by co-morbidities and risk factors for stroke

(2011) Caroline Drake et al.   BRAIN BEHAVIOR AND IMMUNITY

ApoE is required for maintenance of the dentate gyrus neural progenitor pool

(2011) C.-P. Yang et al.   DEVELOPMENT

Involvement of RAGE, MAPK and NF-κB pathways in AGEs-induced MMP-9 activation in HaCaT keratinocytes

(2011) Ping Zhu et al.   EXPERIMENTAL DERMATOLOGY

Attenuation of Brain Damage and Cognitive Impairment by Direct Renin Inhibition in Mice With Chronic Cerebral Hypoperfusion

(2011) Yi-Fei Dong et al.   HYPERTENSION

Apolipoprotein E Regulates the Integrity of Tight Junctions in an Isoform-dependent Manner in anin VitroBlood-Brain Barrier Model

(2011) Kazuchika Nishitsuji et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sphingosine 1-phosphate regulates matrix metalloproteinase-9 expression and breast cell invasion through S1P3-G q coupling

(2011) E.-S. Kim et al.   JOURNAL OF CELL SCIENCE

Influence of matrix metalloproteinase MMP-9 on dendritic spine morphology

(2011) P. Michaluk et al.   JOURNAL OF CELL SCIENCE

Rapid Disruption of Axon-Glial Integrity in Response to Mild Cerebral Hypoperfusion

(2011) M. M. Reimer et al.   JOURNAL OF NEUROSCIENCE

The immune system in atherosclerosis

(2011) Göran K Hansson et al.   NATURE IMMUNOLOGY

Positive correlation between elevated plasma cholesterol levels and cognitive impairments in LDL receptor knockout mice: relevance of cortico-cerebral mitochondrial dysfunction and oxidative stress

(2011) J. de Oliveira et al.   NEUROSCIENCE

Diffuse optical monitoring of repeated cerebral ischemia in mice

(2011) Yu Shang et al.   OPTICS EXPRESS

The Influence of Chronic Cerebral Hypoperfusion on Cognitive Function and Amyloid β Metabolism in APP Overexpressing Mice

(2011) Mahito Yamada et al.   PLoS One

ApoB100/LDLR-/- Hypercholesterolaemic Mice as a Model for Mild Cognitive Impairment and Neuronal Damage

(2011) Carlos Ramírez et al.   PLoS One

Lack of LDL Receptor Enhances Amyloid Deposition and Decreases Glial Response in an Alzheimer's Disease Mouse Model

(2011) Loukia Katsouri et al.   PLoS One

Vascular Contributions to Cognitive Impairment and Dementia

(2011) Philip B. Gorelick et al.   STROKE

Angiogenic and Vasoprotective Effects of Adrenomedullin on Prevention of Cognitive Decline After Chronic Cerebral Hypoperfusion in Mice

(2011) Takakuni Maki et al.   STROKE

Catechin treatment improves cerebrovascular flow-mediated dilation and learning abilities in atherosclerotic mice

(2010) Annick Drouin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Inflammation in neurodegenerative diseases

(2010) Sandra Amor et al.   IMMUNOLOGY

Alterations in Nitric Oxide and Endothelin-1 Bioactivity Underlie Cerebrovascular Dysfunction in ApoE-Deficient Mice

(2010) Kazuo Yamashiro et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cardiomyocyte PDGFR-β signaling is an essential component of the mouse cardiac response to load-induced stress

(2010) Vishnu Chintalgattu et al.   JOURNAL OF CLINICAL INVESTIGATION

Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease

(2010) Anne Joutel et al.   JOURNAL OF CLINICAL INVESTIGATION

Metzincin Proteases and Their Inhibitors: Foes or Friends in Nervous System Physiology?

(2010) S. Rivera et al.   JOURNAL OF NEUROSCIENCE

MRI is a sensitive marker of subtle white matter pathology in hypoperfused mice

(2010) Philip R. Holland et al.   NEUROBIOLOGY OF AGING

Selective white matter pathology induces a specific impairment in spatial working memory

(2010) Robin Coltman et al.   NEUROBIOLOGY OF AGING

Role of neuroinflammation in hypertension-induced brain amyloid pathology

(2010) Daniela Carnevale et al.   NEUROBIOLOGY OF AGING

Chronic cerebral hypoperfusion in a mouse model of Alzheimer's disease: An additional contributing factor of cognitive impairment

(2010) Jin Soo Lee et al.   NEUROSCIENCE LETTERS

Early Protective Effect of Bone Marrow Mononuclear Cells Against Ischemic White Matter Damage Through Augmentation of Cerebral Blood Flow

(2010) Youshi Fujita et al.   STROKE

A Mouse Model Characterizing Features of Vascular Dementia With Hippocampal Atrophy

(2010) Keiko Nishio et al.   STROKE

CADASIL: Experimental Insights From Animal Models

(2010) C. Ayata   STROKE

Chronic cerebral hypoperfusion accelerates amyloid β deposition in APPSwInd transgenic mice

(2009) Hiroshi Kitaguchi et al.   BRAIN RESEARCH

GABAergic Interneuron Dysfunction Impairs Hippocampal Neurogenesis in Adult Apolipoprotein E4 Knockin Mice

(2009) Gang Li et al.   Cell Stem Cell

MEF2 transcriptional activity maintains mitochondrial adaptation in cardiac pressure overload

(2009) Hamid el Azzouzi et al.   EUROPEAN JOURNAL OF HEART FAILURE

Relationship between cerebral blood flow and later cognitive decline in hypertensive patients with cerebral small vessel disease

(2009) Kazuo Kitagawa et al.   HYPERTENSION RESEARCH

Adenosine A2A receptor deficiency exacerbates white matter lesions and cognitive deficits induced by chronic cerebral hypoperfusion in mice

(2009) Wei Duan et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Novel cerebrovascular pathology in mice fed a high cholesterol diet

(2009) Sonia Franciosi et al.   Molecular Neurodegeneration

Carotid Artery Atherosclerosis, MRI Indices of Brain Ischemia, Aging, and Cognitive Impairment

(2009) José R. Romero et al.   STROKE

Increased locomotor activity in mice lacking the low-density lipoprotein receptor

(2008) Gregory A. Elder et al.   BEHAVIOURAL BRAIN RESEARCH

Cerebral Autoregulation: An Overview of Current Concepts and Methodology with Special Focus on the Elderly

(2008) Arenda HEA van Beek et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice

(2008) Lakshmi Thirumangalakudi et al.   JOURNAL OF NEUROCHEMISTRY

Intensity of chronic cerebral hypoperfusion determines white/gray matter injury and cognitive/motor dysfunction in mice

(2008) Kazunori Miki et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Overexpression of Human Apolipoprotein B-100 Induces Severe Neurodegeneration in Transgenic Mice

(2008) Erika Bereczki et al.   JOURNAL OF PROTEOME RESEARCH

Cerebral blood flow MRI in mice using the cardiac-spin-labeling technique

(2008) Eric R. Muir et al.   MAGNETIC RESONANCE IN MEDICINE

Brainstem Concentrations of Cholesterol are not Influenced by Genetic Ablation of the Low-Density Lipoprotein Receptor

(2008) Ameer Y. Taha et al.   NEUROCHEMICAL RESEARCH

Pathophysiology of Neuronal Energy Crisis in Alzheimer’s Disease

(2008) Jack C. de la Torre   Neurodegenerative Diseases

Review: Role of developmental inflammation and blood-brain barrier dysfunction in neurodevelopmental and neurodegenerative diseases

(2008) H. B. Stolp et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Chronic cerebral hypoperfusion induced by right unilateral common carotid artery occlusion causes delayed white matter lesions and cognitive impairment in adult mice

(2007) Kaichi Yoshizaki et al.   EXPERIMENTAL NEUROLOGY

β-Amyloid deposition in brain is enhanced in mouse models of arterial hypertension

(2007) Maria Teresa Gentile et al.   NEUROBIOLOGY OF AGING