Two-Photon Microscopy as a Tool to Study Blood Flow and Neurovascular Coupling in the Rodent Brain

Occlusion of Cortical Ascending Venules Causes Blood Flow Decreases, Reversals in Flow Direction, and Vessel Dilation in Upstream Capillaries

(2011) John Nguyen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Optical coherence tomography for the quantitative study of cerebrovascular physiology

(2011) Vivek J Srinivasan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Photon counting, censor corrections, and lifetime imaging for improved detection in two-photon microscopy

(2011) Jonathan D. Driscoll et al.   JOURNAL OF NEUROPHYSIOLOGY

Absence of Large-Scale Dendritic Plasticity of Layer 5 Pyramidal Neurons in Peri-Infarct Cortex

(2011) R. Mostany et al.   JOURNAL OF NEUROSCIENCE

What Does Local Functional Hyperemia Tell about Local Neuronal Activation?

(2011) N. Jukovskaya et al.   JOURNAL OF NEUROSCIENCE

"Overshoot" of O2 Is Required to Maintain Baseline Tissue Oxygenation at Locations Distal to Blood Vessels

(2011) A. Devor et al.   JOURNAL OF NEUROSCIENCE

Simultaneous two-photon imaging of oxygen and blood flow in deep cerebral vessels

(2011) Jérôme Lecoq et al.   NATURE MEDICINE

Functional ultrasound imaging of the brain

(2011) Emilie Macé et al.   NATURE METHODS

Simultaneous two-photon calcium imaging at different depths with spatiotemporal multiplexing

(2011) Adrian Cheng et al.   NATURE METHODS

Monitoring astrocyte calcium microdomains with improved membrane targeted GCaMP reporters

(2011) Eiji Shigetomi et al.   Neuron Glia Biology

Cortical Microhemorrhages Cause Local Inflammation but Do Not Trigger Widespread Dendrite Degeneration

(2011) Nathanael L. Rosidi et al.   PLoS One

Fluctuating and sensory-induced vasodynamics in rodent cortex extend arteriole capacity

(2011) P. J. Drew et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted mini-strokes produce changes in interhemispheric sensory signal processing that are indicative of disinhibition within minutes

(2011) M. H. Mohajerani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy syndrome mutations increase susceptibility to spreading depression

(2010) Katharina Eikermann-Haerter et al.   ANNALS OF NEUROLOGY

Photoacoustic imaging and characterization of the microvasculature

(2010) Song Hu et al.   JOURNAL OF BIOMEDICAL OPTICS

Two-Photon NADH Imaging Exposes Boundaries of Oxygen Diffusion in Cortical Vascular Supply Regions

(2010) Karl A Kasischke et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

in vivo 3D Morphology of Astrocyte—Vasculature Interactions in the Somatosensory Cortex: Implications for Neurovascular Coupling

(2010) Addason F H McCaslin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Limitations of Collateral Flow after Occlusion of a Single Cortical Penetrating Arteriole

(2010) Nozomi Nishimura et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Temporal Dynamics and Spatial Specificity of Arterial and Venous Blood Volume Changes during Visual Stimulation: Implication for Bold Quantification

(2010) Tae Kim et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Automatic Identification of Fluorescently Labeled Brain Cells for Rapid Functional Imaging

(2010) Ilya Valmianski et al.   JOURNAL OF NEUROPHYSIOLOGY

Vibrissa-Based Object Localization in Head-Fixed Mice

(2010) D. H. O'Connor et al.   JOURNAL OF NEUROSCIENCE

Global and local fMRI signals driven by neurons defined optogenetically by type and wiring

(2010) Jin Hyung Lee et al.   NATURE

Glial and neuronal control of brain blood flow

(2010) David Attwell et al.   NATURE

High-performance genetically targetable optical neural silencing by light-driven proton pumps

(2010) Brian Y. Chow et al.   NATURE

Learning-related fine-scale specificity imaged in motor cortex circuits of behaving mice

(2010) Takaki Komiyama et al.   NATURE

Chronic optical access through a polished and reinforced thinned skull

(2010) Patrick J Drew et al.   NATURE METHODS

Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue

(2010) Sava Sakadžić et al.   NATURE METHODS

Imaging brain electric signals with genetically targeted voltage-sensitive fluorescent proteins

(2010) Walther Akemann et al.   NATURE METHODS

Functional imaging of hippocampal place cells at cellular resolution during virtual navigation

(2010) Daniel A Dombeck et al.   NATURE NEUROSCIENCE

Thinned-skull cranial window technique for long-term imaging of the cortex in live mice

(2010) Guang Yang et al.   Nature Protocols

Frequency-dependent neural activity, CBF, and BOLD fMRI to somatosensory stimuli in isoflurane-anesthetized rats

(2010) Tae Kim et al.   NEUROIMAGE

Membrane Potential Dynamics of GABAergic Neurons in the Barrel Cortex of Behaving Mice

(2010) Luc J. Gentet et al.   NEURON

Imaging extrasynaptic glutamate dynamics in the brain

(2010) Y. Okubo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pericytes in capillaries are contractile in vivo, but arterioles mediate functional hyperemia in the mouse brain

(2010) F. Fernandez-Klett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Topological basis for the robust distribution of blood to rodent neocortex

(2010) Pablo Blinder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cortical depth-specific microvascular dilation underlies laminar differences in blood oxygenation level-dependent functional MRI signal

(2010) P. Tian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Active Dilation of Penetrating Arterioles Restores Red Blood Cell Flux to Penumbral Neocortex after Focal Stroke

(2009) Andy Y Shih et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Rapid determination of particle velocity from space-time images using the Radon transform

(2009) Patrick J. Drew et al.   JOURNAL OF COMPUTATIONAL NEUROSCIENCE

Stimulus-Induced Changes in Blood Flow and 2-Deoxyglucose Uptake Dissociate in Ipsilateral Somatosensory Cortex

(2009) A. Devor et al.   JOURNAL OF NEUROSCIENCE

Correlations of Neuronal and Microvascular Densities in Murine Cortex Revealed by Direct Counting and Colocalization of Nuclei and Vessels

(2009) P. S. Tsai et al.   JOURNAL OF NEUROSCIENCE

Functional Clustering of Neurons in Motor Cortex Determined by Cellular Resolution Imaging in Awake Behaving Mice

(2009) D. A. Dombeck et al.   JOURNAL OF NEUROSCIENCE

Odor-Evoked Oxygen Consumption by Action Potential and Synaptic Transmission in the Olfactory Bulb

(2009) J. Lecoq et al.   JOURNAL OF NEUROSCIENCE

Anticipatory haemodynamic signals in sensory cortex not predicted by local neuronal activity

(2009) Yevgeniy B. Sirotin et al.   NATURE

Temporally precise in vivo control of intracellular signalling

(2009) Raag D. Airan et al.   NATURE

In vivo fluorescence imaging with high-resolution microlenses

(2009) Robert P J Barretto et al.   NATURE METHODS

Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators

(2009) Lin Tian et al.   NATURE METHODS

An in vivo biosensor for neurotransmitter release and in situ receptor activity

(2009) Quoc-Thang Nguyen et al.   NATURE NEUROSCIENCE

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Long-term, high-resolution imaging in the mouse neocortex through a chronic cranial window

(2009) Anthony Holtmaat et al.   Nature Protocols

Remote Control of Neuronal Activity in Transgenic Mice Expressing Evolved G Protein-Coupled Receptors

(2009) Georgia M. Alexander et al.   NEURON

Deep tissue multiphoton microscopy using longer wavelength excitation

(2009) Demirhan Kobat et al.   OPTICS EXPRESS

Two-photon microscopy with simultaneous standard and extended depth of field using a tunable acoustic gradient-index lens

(2009) Nicolas Olivier et al.   OPTICS LETTERS

Depth-resolved microscopy of cortical hemodynamics with optical coherence tomography

(2009) Vivek J. Srinivasan et al.   OPTICS LETTERS

Imaging rapid redistribution of sensory-evoked depolarization through existing cortical pathways after targeted stroke in mice

(2009) Albrecht Sigler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Visually evoked activity in cortical cells imaged in freely moving animals

(2009) J. Sawinski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice

(2009) K. V. Kuchibhotla et al.   SCIENCE

Severe Blood–Brain Barrier Disruption and Surrounding Tissue Injury

(2009) Bo Chen et al.   STROKE

Oxygen Microscopy by Two-Photon-Excited Phosphorescence

(2008) Olga S. Finikova et al.   CHEMPHYSCHEM

Do in vivo Experimental Models Reflect Human Cerebral Small Vessel Disease? a Systematic Review

(2008) Atticus H Hainsworth et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Two-Photon Imaging of Stroke Onset In Vivo Reveals That NMDA-Receptor Independent Ischemic Depolarization Is the Major Cause of Rapid Reversible Damage to Dendrites and Spines

(2008) T. H. Murphy et al.   JOURNAL OF NEUROSCIENCE

In Vivo Calcium Imaging Reveals Functional Rewiring of Single Somatosensory Neurons after Stroke

(2008) I. R. Winship et al.   JOURNAL OF NEUROSCIENCE

Two-photon imaging of spatially extended neuronal network dynamics with high temporal resolution

(2008) Kyle P. Lillis et al.   JOURNAL OF NEUROSCIENCE METHODS

Tracheotomy improves experiment success rate in mice during urethane anesthesia and stereotaxic surgery

(2008) Olve Moldestad et al.   JOURNAL OF NEUROSCIENCE METHODS

Brain metabolism dictates the polarity of astrocyte control over arterioles

(2008) Grant R. J. Gordon et al.   NATURE

A genetically encoded calcium indicator for chronic in vivo two-photon imaging

(2008) Marco Mank et al.   NATURE METHODS

Finding coherence in spontaneous oscillations

(2008) Patrick J Drew et al.   NATURE NEUROSCIENCE

Interhemispheric correlations of slow spontaneous neuronal fluctuations revealed in human sensory cortex

(2008) Yuval Nir et al.   NATURE NEUROSCIENCE

Three-dimensional random access multiphoton microscopy for functional imaging of neuronal activity

(2008) Gaddum Duemani Reddy et al.   NATURE NEUROSCIENCE

Population imaging of ongoing neuronal activity in the visual cortex of awake rats

(2008) David S Greenberg et al.   NATURE NEUROSCIENCE

Coupling of Neural Activity to Blood Flow in Olfactory Glomeruli Is Mediated by Astrocytic Pathways

(2008) Gabor C. Petzold et al.   NEURON

Simultaneous multifocal, multiphoton, photon counting microscopy

(2008) Ramón Carriles et al.   OPTICS EXPRESS

High-speed varifocal imaging with a tunable acoustic gradient index of refraction lens

(2008) Alexandre Mermillod-Blondin et al.   OPTICS LETTERS

High-Resolution Labeling and Functional Manipulation of Specific Neuron Types in Mouse Brain by Cre-Activated Viral Gene Expression

(2008) Sandra J. Kuhlman et al.   PLoS One

Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice

(2008) P. A. Murphy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prevalence and Correlates of Silent Cerebral Infarcts in the Framingham Offspring Study

(2008) Rohit R. Das et al.   STROKE