Identification of the PKR Nuclear Interactome Reveals Roles in Ribosome Biogenesis, mRNA Processing and Cell Division

PKR regulates proliferation, differentiation, and survival of murine hematopoietic stem/progenitor cells

(2013) X. Liu et al.   BLOOD

Role of Stress Granules and RNA-Binding Proteins in Neurodegeneration: A Mini-Review

(2013) Tara Vanderweyde et al.   GERONTOLOGY

ADAR Regulates RNA Editing, Transcript Stability, and Gene Expression

(2013) Isabel X. Wang et al.   Cell Reports

Alterations in the ribosomal machinery in cancer and hematologic disorders

(2012) Niraj Shenoy et al.   Journal of Hematology & Oncology

Emerging roles of the spliceosomal machinery in myelodysplastic syndromes and other hematological disorders

(2012) V Visconte et al.   LEUKEMIA

ATP-independent diffusion of double-stranded RNA binding proteins

(2012) H. R. Koh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Progress towards Mechanism-Based Treatment for Diamond-Blackfan Anemia

(2012) Sara E. Sjögren et al.   TheScientificWorldJOURNAL

Identifying and exploiting defects in the Fanconi anemia/BRCA pathway in oncology

(2012) Shane R. Stecklein et al.   Translational Research

Protein Kinase R as Mediator of the Effects of Interferon (IFN) γ and Tumor Necrosis Factor (TNF) α on Normal and Dysplastic Hematopoiesis

(2011) Bhumika Sharma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

iProphet: Multi-level Integrative Analysis of Shotgun Proteomic Data Improves Peptide and Protein Identification Rates and Error Estimates

(2011) David Shteynberg et al.   MOLECULAR & CELLULAR PROTEOMICS

Gene expression profiles from discordant monozygotic twins suggest that molecular pathways are shared among multiple systemic autoimmune diseases

(2011) Terrance P O'Hanlon et al.   ARTHRITIS RESEARCH & THERAPY

Regulatory Circuitries Coordinated by Transcription Factors and microRNAs at the Cornerstone of Hematopoietic Stem Cell Self-Renewal and Differentiation

(2011) Linda M. Starnes et al.   Current Stem Cell Research & Therapy

Inhibition of RNA-dependent protein kinase (PKR) leads to cancer cell death and increases chemosensitivity

(2010) Abujiang Pataer et al.   CANCER BIOLOGY & THERAPY

Phosphorylation of the NFAR proteins by the dsRNA-dependent protein kinase PKR constitutes a novel mechanism of translational regulation and cellular defense

(2010) A. Harashima et al.   GENES & DEVELOPMENT

IL-2 mRNA Stabilization upon PMA Stimulation Is Dependent on NF90-Ser647 Phosphorylation by Protein Kinase C I

(2010) P. Zhu et al.   JOURNAL OF IMMUNOLOGY

Multiple forms of PKR present in the nuclei of acute leukemia cells represent an active kinase that is responsive to stress

(2010) W L Blalock et al.   LEUKEMIA

Entrez Gene: gene-centered information at NCBI

(2010) D. Maglott et al.   NUCLEIC ACIDS RESEARCH

Ongoing and future developments at the Universal Protein Resource

(2010)   NUCLEIC ACIDS RESEARCH

The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored

(2010) D. Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Interaction of Double-stranded RNA-dependent Protein Kinase (PKR) with the Death Receptor Signaling Pathway in Amyloid β (Aβ)-treated Cells and in APPSLPS1 Knock-in Mice

(2009) Julien Couturier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PKR activity is required for acute leukemic cell maintenance and growth: A role for PKR-mediated phosphatase activity to regulate GSK-3 phosphorylation

(2009) William L. Blalock et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Essential role of the RNA-binding protein HuR in progenitor cell survival in mice

(2009) Mallika Ghosh et al.   JOURNAL OF CLINICAL INVESTIGATION

Neuronal Phosphorylated RNA-Dependent Protein Kinase in Creutzfeldt-Jakob Disease

(2009) Claire Paquet et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

ADAR1 is required for hematopoietic progenitor cell survival via RNA editing

(2009) R. XuFeng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PKR is activated in MDS patients and its subcellular localization depends on disease severity

(2008) M Y Follo et al.   LEUKEMIA

ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling

(2008) Jochen C Hartner et al.   NATURE IMMUNOLOGY

NFAR-1 and -2 modulate translation and are required for efficient host defense

(2008) I. Pfeifer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs

(2008) D. Weidensdorfer et al.   RNA