Phosphorylation of PRAS40-Thr246 Involved in Renal Lipid Accumulation of Diabetes

Inflammation and the pathogenesis of diabetic nephropathy

(2012) Jun Wada et al.   CLINICAL SCIENCE

Identification of Akt-independent Regulation of Hepatic Lipogenesis by Mammalian Target of Rapamycin (mTOR) Complex 2

(2012) Minsheng Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PI3K/Akt pathway mediates high glucose-induced lipid accumulation in human renal proximal tubular cells via spliced XBP-1

(2012) Song Zhao et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

PRAS40 Is an Integral Regulatory Component of Erythropoietin mTOR Signaling and Cytoprotection

(2012) Zhao Zhong Chong et al.   PLoS One

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice

(2011) Yu Li et al.   Cell Metabolism

High glucose upregulation of early-onset Parkinson's disease protein DJ-1 integrates the PRAS40/TORC1 axis to mesangial cell hypertrophy

(2011) Falguni Das et al.   CELLULAR SIGNALLING

PI3K Functions in Cancer Progression, Anticancer Immunity and Immune Evasion by Tumors

(2011) Francesco Dituri et al.   Clinical & Developmental Immunology

PTEN ameliorates high glucose-induced lipid deposits through regulating SREBP-1/FASN/ACC pathway in renal proximal tubular cells

(2011) Jun Hao et al.   EXPERIMENTAL CELL RESEARCH

PI3K/Akt pathway mediates high glucose-induced lipogenesis and extracellular matrix accumulation in HKC cells through regulation of SREBP-1 and TGF-β1

(2011) Jun Hao et al.   HISTOCHEMISTRY AND CELL BIOLOGY

PRAS40 acts as a nodal regulator of high glucose-induced TORC1 activation in glomerular mesangial cell hypertrophy

(2010) Nirmalya Dey et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Hepatitis C virus genotype-3a core protein enhances sterol regulatory element-binding protein-1 activity through the phosphoinositide 3-kinase-Akt-2 pathway

(2010) C. Jackel-Cram et al.   JOURNAL OF GENERAL VIROLOGY

Hepatitis C Virus Nonstructural 4B Protein Modulates Sterol Regulatory Element-binding Protein Signaling via the AKT Pathway

(2009) Chul-Yong Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In vivo and in vitro effects of SREBP-1 on diabetic renal tubular lipid accumulation and RNAi-mediated gene silencing study

(2008) Hao Jun et al.   HISTOCHEMISTRY AND CELL BIOLOGY