AZD9291 promotes autophagy and inhibits PI3K/Akt pathway in NSCLC cancer cells
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Title
AZD9291 promotes autophagy and inhibits PI3K/Akt pathway in NSCLC cancer cells
Authors
Keywords
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Journal
JOURNAL OF CELLULAR BIOCHEMISTRY
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2018-08-28
DOI
10.1002/jcb.27434
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Note: Only part of the references are listed.- Shikonin induces necroptosis by reactive oxygen species activation in nasopharyngeal carcinoma cell line CNE-2Z
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- (2017) Zheng-Hai Tang et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
- (2016) Daniel J Klionsky et al. Autophagy
- Preclinical Comparison of Osimertinib with Other EGFR-TKIs in EGFR-Mutant NSCLC Brain Metastases Models, and Early Evidence of Clinical Brain Metastases Activity
- (2016) P. Ballard et al. CLINICAL CANCER RESEARCH
- Osimertinib: First Global Approval
- (2016) Sarah L. Greig DRUGS
- Clinical Cancer Advances 2016: Annual Report on Progress Against Cancer From the American Society of Clinical Oncology
- (2016) Don S. Dizon et al. JOURNAL OF CLINICAL ONCOLOGY
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- Osimertinib for EGFR T790M mutation-positive non-small cell lung cancer
- (2016) Kenzo Soejima et al. Expert Review of Clinical Pharmacology
- Osimertinib in the treatment of patients with epidermal growth factor receptor T790M mutation-positive metastatic non-small cell lung cancer: clinical trial evidence and experience
- (2016) Ivana Sullivan et al. Therapeutic Advances in Respiratory Disease
- EGFR-independent autophagy induction with gefitinib and enhancement of its cytotoxic effect by targeting autophagy with clarithromycin in non-small cell lung cancer cells
- (2015) Shohei Sugita et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- Acquired EGFR C797S mutation mediates resistance to AZD9291 in non–small cell lung cancer harboring EGFR T790M
- (2015) Kenneth S Thress et al. NATURE MEDICINE
- AZD9291 in EGFR Inhibitor–Resistant Non–Small-Cell Lung Cancer
- (2015) Pasi A. Jänne et al. NEW ENGLAND JOURNAL OF MEDICINE
- Autophagy contributes to gefitinib-induced glioma cell growth inhibition
- (2014) Cheng-Yi Chang et al. EXPERIMENTAL CELL RESEARCH
- The PI3k inhibitors: new hopes in the battle against advanced NSCLC
- (2014) Paola Sacco Frontiers in Bioscience-Landmark
- PIK3CA Mutations Frequently Coexist with EGFR/KRAS Mutations in Non-Small Cell Lung Cancer and Suggest Poor Prognosis in EGFR/KRAS Wildtype Subgroup
- (2014) Lei Wang et al. PLoS One
- Autophagosome-Mediated EGFR Down-Regulation Induced by the CK2 Inhibitor Enhances the Efficacy of EGFR-TKI on EGFR-Mutant Lung Cancer Cells with Resistance by T790M
- (2014) Kwang Sup So et al. PLoS One
- AZD9291, an Irreversible EGFR TKI, Overcomes T790M-Mediated Resistance to EGFR Inhibitors in Lung Cancer
- (2014) D. A. E. Cross et al. Cancer Discovery
- Review of EGFR TKIs in Metastatic NSCLC, Including Ongoing Trials
- (2014) Barbara Melosky Frontiers in Oncology
- EGFR-Mediated Beclin 1 Phosphorylation in Autophagy Suppression, Tumor Progression, and Tumor Chemoresistance
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- Structure- and Reactivity-Based Development of Covalent Inhibitors of the Activating and Gatekeeper Mutant Forms of the Epidermal Growth Factor Receptor (EGFR)
- (2013) Richard A. Ward et al. JOURNAL OF MEDICINAL CHEMISTRY
- Erlotinib-induced autophagy in epidermal growth factor receptor mutated non-small cell lung cancer
- (2013) Yuan-yuan Li et al. LUNG CANCER
- Induction of Autophagy Is an Early Response to Gefitinib and a Potential Therapeutic Target in Breast Cancer
- (2013) Wieslawa H. Dragowska et al. PLoS One
- EGFR Tyrosine Kinase Inhibitors Activate Autophagy as a Cytoprotective Response in Human Lung Cancer Cells
- (2011) Weidong Han et al. PLoS One
- The PI3-K/AKT-Pathway and Radiation Resistance Mechanisms in Non-small Cell Lung Cancer
- (2009) Olga C.J. Schuurbiers et al. Journal of Thoracic Oncology
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