Mechanisms underlying 3-bromopyruvate-induced cell death in colon cancer

3-Bromopyruvate induces apoptosis in breast cancer cells by downregulating Mcl-1 through the PI3K/Akt signaling pathway

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RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3

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Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases

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Ultrasound-guided direct delivery of 3-bromopyruvate blocks tumor progression in an orthotopic mouse model of human pancreatic cancer

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Autophagy Guards Against Cisplatin-Induced Acute Kidney Injury

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Targeting aerobic glycolysis: 3-bromopyruvate as a promising anticancer drug

(2012) Simone Cardaci et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

3-bromopyruvate: Targets and outcomes

(2012) Maria C. Shoshan   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

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Autophagy: Renovation of Cells and Tissues

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Autophagy in tumorigenesis and energy metabolism: friend by day, foe by night

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The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance

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Miltefosine Induces Apoptosis-Like Cell Death in Yeast via Cox9p in Cytochrome c Oxidase

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3-Bromopyruvate: A New Targeted Antiglycolytic Agent and a Promise for Cancer Therapy

(2010) S. Ganapathy-Kanniappan et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

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The combination of the novel glycolysis inhibitor 3-BrOP and rapamycin is effective against neuroblastoma

(2010) Alejandro G. Levy et al.   INVESTIGATIONAL NEW DRUGS

Role of mitochondria-associated hexokinase II in cancer cell death induced by 3-bromopyruvate

(2009) Zhao Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

(2009) YoungSik Cho et al.   CELL

Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

(2009) Sudan He et al.   CELL

RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

(2009) D.-W. Zhang et al.   SCIENCE

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Apoptosome-deficient Cells Lose Cytochrome c through Proteasomal Degradation but Survive by Autophagy-dependent Glycolysis

(2008) Elisabetta Ferraro et al.   MOLECULAR BIOLOGY OF THE CELL