Cytosolic chloride ion is a key factor in lysosomal acidification and function of autophagy in human gastric cancer cell

Accumulation of autophagosomes in breast cancer cells induces TRAIL resistance through downregulation of surface expression of death receptors 4 and 5

(2015) Xu Di et al.   Oncotarget

A regulatory role of K+–Cl− cotransporter in the cell cycle progression of breast cancer MDA-MB-231 cells

(2013) Maki Kitagawa et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Thymoquinone Inhibits Autophagy and Induces Cathepsin-Mediated, Caspase-Independent Cell Death in Glioblastoma Cells

(2013) Ira O. Racoma et al.   PLoS One

Enhancement of tubulin polymerization by Cl−-induced blockade of intrinsic GTPase

(2012) Ken-ichi Nakajima et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cathepsin D inhibits oxidative stress-induced cell death via activation of autophagy in cancer cells

(2012) Young-Sool Hah et al.   CANCER LETTERS

An Inhibitor of Na+/H+Exchanger (NHE), Ethyl-Isopropyl Amiloride (EIPA), Diminishes Proliferation of MKN28 Human Gastric Cancer Cells by Decreasing the Cytosolic Cl-Concentration via DIDS-Sensitive Pathways

(2012) Shigekuni Hosogi et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Targeting the PI3K signaling pathway in cancer therapy

(2012) Chandra Bartholomeusz et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Biogenesis and Cargo Selectivity of Autophagosomes

(2011) Hilla Weidberg et al.   Annual Review of Biochemistry

Selective autophagy mediated by autophagic adapter proteins

(2011) Terje Johansen et al.   Autophagy

Akt, FoxO and regulation of apoptosis

(2011) Xinbo Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Genistein enhances the NGF-induced neurite outgrowth

(2011) Ken-ichi Nakajima et al.   BIOMEDICAL RESEARCH-TOKYO

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Quercetin Stimulates NGF-induced Neurite Outgrowth in PC12 Cells via Activation of Na+/K+/2Cl- Cotransporter

(2011) Ken-ichi Nakajima et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

ClC-7 is a slowly voltage-gated 2Cl−/1H+-exchanger and requires Ostm1 for transport activity

(2011) Lilia Leisle et al.   EMBO JOURNAL

Pancreatic cancers require autophagy for tumor growth

(2011) S. Yang et al.   GENES & DEVELOPMENT

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis

(2011) J. Y. Guo et al.   GENES & DEVELOPMENT

Crohn's disease: NOD2, autophagy and ER stress converge

(2011) T. Fritz et al.   GUT

Regulation of Epithelial Sodium Transport via Epithelial Na+Channel

(2011) Yoshinori Marunaka et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance

(2010) Ling Yang et al.   Cell Metabolism

Chloride Ion Modulates Cell Proliferation of Human Androgen-independent Prostatic Cancer Cell

(2010) Kenji Hiraoka et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lysosomal Pathology and Osteopetrosis upon Loss of H+-Driven Lysosomal Cl- Accumulation

(2010) S. Weinert et al.   SCIENCE

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

The Cl-/H+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes

(2008) Austin R. Graves et al.   NATURE

Chloride ions control the G1/S cell-cycle checkpoint by regulating the expression of p21 through a p53-independent pathway in human gastric cancer cells

(2007) Hiroaki Miyazaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS