Advances in the treatment of acute graft-versus-host disease

Hydrogen therapy may be an effective and specific novel treatment for Acute Graft-versus-host disease (GVHD)

(2013) Liren Qian et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Administration of Hydrogen-Rich Saline Protects Mice From Lethal Acute Graft-Versus-Host Disease (aGVHD)

(2013) Liren Qian et al.   TRANSPLANTATION

Clinical Applications for Biomarkers of Acute and Chronic Graft-versus-Host Disease

(2012) John E. Levine et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

First- and Second-Line Systemic Treatment of Acute Graft-versus-Host Disease: Recommendations of the American Society of Blood and Marrow Transplantation

(2012) Paul J. Martin et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Discovery and validation of graft-versus-host disease biomarkers

(2012) S. Paczesny   BLOOD

Diagnosis and management of acute graft-versus-host disease

(2012) Fiona L. Dignan et al.   BRITISH JOURNAL OF HAEMATOLOGY

GSK3 inhibition prevents lethal GVHD in mice

(2012) Guy Klamer et al.   EXPERIMENTAL HEMATOLOGY

Antigen-presenting cell–derived complement modulates graft-versus-host disease

(2012) Wing-Hong Kwan et al.   JOURNAL OF CLINICAL INVESTIGATION

Blockade of Lymphocyte Chemotaxis in Visceral Graft-versus-Host Disease

(2012) Ran Reshef et al.   NEW ENGLAND JOURNAL OF MEDICINE

Concise Review: The Role of Hematopoietic Stem Cell Transplantation in the Treatment of Acute Myeloid Leukemia

(2012) Betty K. Hamilton et al.   STEM CELLS

T Cell–Depleted Unrelated Donor Stem Cell Transplantation Provides Favorable Disease-Free Survival for Adults with Hematologic Malignancies

(2011) Ann A. Jakubowski et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Low Risk of Chronic Graft-versus-Host Disease and Relapse Associated with T Cell–Depleted Peripheral Blood Stem Cell Transplantation for Acute Myelogenous Leukemia in First Remission: Results of the Blood and Marrow Transplant Clinical Trials Network Protocol 0303

(2011) Steven M. Devine et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Abrogation of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL

(2011) A. M. Hanash et al.   BLOOD

Small vessels, big trouble in the kidneys and beyond: hematopoietic stem cell transplantation-associated thrombotic microangiopathy

(2011) B. L. Laskin et al.   BLOOD

Novel treatment concepts for graft-versus-host disease

(2011) D. Wolf et al.   BLOOD

Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation

(2011) M. Di Ianni et al.   BLOOD

Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation

(2011) Daigo Hashimoto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Danger signals activating innate immunity in graft-versus-host disease

(2011) Robert Zeiser et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Antithymocyte globulin for acute-graft-versus-host-disease prophylaxis in patients undergoing allogeneic hematopoietic cell transplantation: a systematic review

(2011) A Kumar et al.   LEUKEMIA

A Randomized Phase II Trial Comparing Tacrolimus and Mycophenolate Mofetil to Tacrolimus and Methotrexate for Acute Graft-versus-Host Disease Prophylaxis

(2010) Janelle Perkins et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

The best endpoint for acute GVHD treatment trials

(2010) M. L. MacMillan et al.   BLOOD

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

(2010) C. G. Brunstein et al.   BLOOD

Therapy of steroid-refractory acute GVHD with CD52 antibody alemtuzumab is effective

(2010) N Schub et al.   BONE MARROW TRANSPLANTATION

High-dose, post-transplantation cyclophosphamide to promote graft-host tolerance after allogeneic hematopoietic stem cell transplantation

(2010) Leo Luznik et al.   IMMUNOLOGIC RESEARCH

Effectiveness of Hydrogen Rich Water on Antioxidant Status of Subjects with Potential Metabolic Syndrome—An Open Label Pilot Study

(2010) Atsunori Nakao et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Management of Acute Graft-Versus-Host Disease in Children

(2010) Paul A. Carpenter et al.   PEDIATRIC CLINICS OF NORTH AMERICA

Biological safety of neutral-pH hydrogen-enriched electrolyzed water upon mutagenicity, genotoxicity and subchronic oral toxicity

(2010) Yasukazu Saitoh et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Sirolimus as Primary Treatment of Acute Graft-versus-Host Disease following Allogeneic Hematopoietic Cell Transplantation

(2009) Joseph Pidala et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Adult Human Mesenchymal Stem Cells Added to Corticosteroid Therapy for the Treatment of Acute Graft-versus-Host Disease

(2009) Partow Kebriaei et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

A Phase III Study of Infliximab and Corticosteroids for the Initial Treatment of Acute Graft-versus-Host Disease

(2009) Daniel R. Couriel et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Graft-versus-Host Disease Prophylaxis with Tacrolimus and Mycophenolate Mofetil in HLA-Matched Nonmyeloablative Transplant Recipients Is Associated with Very Low Incidence of GVHD and Nonrelapse Mortality

(2009) Waleed Sabry et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Should Methotrexate plus Calcineurin Inhibitors Be Considered Standard of Care for Prophylaxis of acute Graft-versus-Host Disease?

(2009) Rainer Storb et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Bortezomib, tacrolimus, and methotrexate for prophylaxis of graft-versus-host disease after reduced-intensity conditioning allogeneic stem cell transplantation from HLA-mismatched unrelated donors

(2009) J. Koreth et al.   BLOOD

IL-21 blockade reduces graft-versus-host disease mortality by supporting inducible T regulatory cell generation

(2009) C. Bucher et al.   BLOOD

Etanercept, mycophenolate, denileukin, or pentostatin plus corticosteroids for acute graft-versus-host disease: a randomized phase 2 trial from the Blood and Marrow Transplant Clinical Trials Network

(2009) A. M. Alousi et al.   BLOOD

Sirolimus for treatment of steroid-refractory acute graft-versus-host disease

(2009) D Hoda et al.   BONE MARROW TRANSPLANTATION

Therapy with mycophenolate mofetil for refractory acute and chronic GVHD

(2009) T Furlong et al.   BONE MARROW TRANSPLANTATION

Mycophenolate mofetil for the management of steroid-refractory acute graft vs host disease

(2009) J Pidala et al.   BONE MARROW TRANSPLANTATION

Treatment of acute myeloid leukemia with hematopoietic stem cell transplantation

(2009) Cortney V Jones et al.   Future Oncology

Using histone deacetylase inhibitors to enhance Foxp3+ regulatory T-cell function and induce allograft tolerance

(2009) Liqing Wang et al.   IMMUNOLOGY AND CELL BIOLOGY

Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I–II study

(2009) Fabio Ciceri et al.   LANCET ONCOLOGY

Standard graft-versus-host disease prophylaxis with or without anti-T-cell globulin in haematopoietic cell transplantation from matched unrelated donors: a randomised, open-label, multicentre phase 3 trial

(2009) Jürgen Finke et al.   LANCET ONCOLOGY

Addition of Infliximab to Standard Acute Graft-versus-Host Disease Prophylaxis following Allogeneic Peripheral Blood Cell Transplantation

(2008) Mehdi Hamadani et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Hematopoietic Stem Cell Transplantation in Adults with Acute Myeloid Leukemia

(2008) Mehdi Hamadani et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Initial therapy of acute graft-versus-host disease with low-dose prednisone does not compromise patient outcomes

(2008) M. Mielcarek et al.   BLOOD

Extracorporeal photopheresis for the treatment of steroid refractory acute GVHD

(2008) P Perfetti et al.   BONE MARROW TRANSPLANTATION

Treatment of refractory acute GVHD with third-party MSC expanded in platelet lysate-containing medium

(2008) M von Bonin et al.   BONE MARROW TRANSPLANTATION

Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study

(2008) Katarina Le Blanc et al.   LANCET

Alemtuzumab for the Treatment of Steroid-Refractory Acute Graft-Versus-Host Disease

(2007) David Gómez-Almaguer et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

The impact of regulatory T cells on T-cell immunity following hematopoietic cell transplantation

(2007) V. H. Nguyen et al.   BLOOD

Application of multipotent mesenchymal stromal cells in pediatric patients following allogeneic stem cell transplantation

(2007) Ingo Müller et al.   BLOOD CELLS MOLECULES AND DISEASES