DrosophilaSirt2/mammalian SIRT3 deacetylates ATP synthase β and regulates complex V activity

Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways

(2013) M. J. Rardin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Survival Response to Increased Ceramide Involves Metabolic Adaptation through Novel Regulators of Glycolysis and Lipolysis

(2013) Niraj K. Nirala et al.   PLoS Genetics

Regulation of mitochondrial FoF1ATPase activity by Sirt3-catalyzed deacetylation and its deficiency in human cells harboring 4977bp deletion of mitochondrial DNA

(2012) Yu-Ting Wu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrial Protein Acylation and Intermediary Metabolism: Regulation by Sirtuins and Implications for Metabolic Disease

(2012) John C. Newman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exploring the therapeutic space around NAD+

(2012) Riekelt H. Houtkooper et al.   JOURNAL OF CELL BIOLOGY

Mechanistic insights into the regulation of metabolic enzymes by acetylation

(2012) Yue Xiong et al.   JOURNAL OF CELL BIOLOGY

Calorie Restriction and SIRT3 Trigger Global Reprogramming of the Mitochondrial Protein Acetylome

(2012) Alexander S. Hebert et al.   MOLECULAR CELL

Proteomic Investigations of Lysine Acetylation Identify Diverse Substrates of Mitochondrial Deacetylase Sirt3

(2012) Eri Maria Sol et al.   PLoS One

Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial proteins without affecting global metabolic homeostasis

(2012) Pablo J. Fernandez-Marcos et al.   Scientific Reports

dSir2 in the Adult Fat Body, but Not in Muscles, Regulates Life Span in a Diet-Dependent Manner

(2012) Kushal Kr. Banerjee et al.   Cell Reports

SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1α Destabilization

(2011) Lydia W.S. Finley et al.   CANCER CELL

Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice

(2011) Jun Yoshino et al.   Cell Metabolism

Caloric Restriction Primes Mitochondria for Ischemic Stress by Deacetylating Specific Mitochondrial Proteins of the Electron Transport Chain

(2011) Ken Shinmura et al.   CIRCULATION RESEARCH

The Kynurenine Pathway Modulates Neurodegeneration in a Drosophila Model of Huntington's Disease

(2011) Susanna Campesan et al.   CURRENT BIOLOGY

Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS

(2011) Yaohui Chen et al.   EMBO REPORTS

Sphingosine kinases and their metabolites modulate endolysosomal trafficking in photoreceptors

(2011) Ikuko Yonamine et al.   JOURNAL OF CELL BIOLOGY

Ceramides as modulators of cellular and whole-body metabolism

(2011) Benjamin T. Bikman et al.   JOURNAL OF CLINICAL INVESTIGATION

Succinate Dehydrogenase Is a Direct Target of Sirtuin 3 Deacetylase Activity

(2011) Lydia W. S. Finley et al.   PLoS One

Proteome-Wide Mapping of the Drosophila Acetylome Demonstrates a High Degree of Conservation of Lysine Acetylation

(2011) B. T. Weinert et al.   Science Signaling

Mammalian Sirtuins: Biological Insights and Disease Relevance

(2010) Marcia C. Haigis et al.   Annual Review of Pathology-Mechanisms of Disease

ChIPpeakAnno: a Bioconductor package to annotate ChIP-seq and ChIP-chip data

(2010) Lihua J Zhu et al.   BMC BIOINFORMATICS

SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress

(2010) Hyun-Seok Kim et al.   CANCER CELL

Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction

(2010) Shinichi Someya et al.   CELL

Calorie Restriction Reduces Oxidative Stress by SIRT3-Mediated SOD2 Activation

(2010) Xiaolei Qiu et al.   Cell Metabolism

SIRT3 Deacetylates Mitochondrial 3-Hydroxy-3-Methylglutaryl CoA Synthase 2 and Regulates Ketone Body Production

(2010) Tadahiro Shimazu et al.   Cell Metabolism

The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways

(2010) Riekelt H. Houtkooper et al.   ENDOCRINE REVIEWS

Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress

(2010) Randa Tao et al.   MOLECULAR CELL

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

(2010) Matthew D. Hirschey et al.   NATURE

Generation of acetyllysine antibodies and affinity enrichment of acetylated peptides

(2010) Kun-Liang Guan et al.   Nature Protocols

SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis

(2010) Ruth Luthi-Carter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Cellular Metabolism by Protein Lysine Acetylation

(2010) S. Zhao et al.   SCIENCE

Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases

(2010) Shin-ichiro Imai et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

A Buoyancy-Based Screen of Drosophila Larvae for Fat-Storage Mutants Reveals a Role for Sir2 in Coupling Fat Storage to Nutrient Availability

(2010) Tânia Reis et al.   PLoS Genetics

Regulation of Succinate Dehydrogenase Activity by SIRT3 in Mammalian Mitochondria

(2009) Huseyin Cimen et al.   BIOCHEMISTRY

Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice

(2009) Xin Wang et al.   JOURNAL OF CELL BIOLOGY

Improved visualization of protein consensus sequences by iceLogo

(2009) Niklaas Colaert et al.   NATURE METHODS

Ceramide kinase regulates phospholipase C and phosphatidylinositol 4, 5, bisphosphate in phototransduction

(2009) U. Dasgupta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The structure of the membrane extrinsic region of bovine ATP synthase

(2009) D. M. Rees et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

Principles of bioactive lipid signalling: lessons from sphingolipids

(2008) Yusuf A. Hannun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cell-Nonautonomous Function of Ceramidase in Photoreceptor Homeostasis

(2008) Jairaj K. Acharya et al.   NEURON

Sir2 mediates apoptosis through JNK-dependent pathways in Drosophila

(2008) A. J. Griswold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

(2008) B.-H. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA