S6K1 inhibition enhances tamoxifen-induced cell death in MCF-7 cells through translational inhibition of Mcl-1 and survivin

Inhibition of S6K1 enhances glucose deprivation-induced cell death via downregulation of anti-apoptotic proteins in MCF-7 breast cancer cells

(2013) Ha-Na Choi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

5,6-Epoxy-cholesterols contribute to the anticancer pharmacology of Tamoxifen in breast cancer cells

(2013) Gregory Segala et al.   BIOCHEMICAL PHARMACOLOGY

Cholesterol metabolism and resistance to tamoxifen

(2012) Marc Poirot et al.   CURRENT OPINION IN PHARMACOLOGY

Estrogenic regulation of S6K1 expression creates a positive regulatory loop in control of breast cancer cell proliferation

(2012) D M Maruani et al.   ONCOGENE

Sorafenib induces apoptotic cell death in human non-small cell lung cancer cells by down-regulating mammalian target of rapamycin (mTOR)-dependent survivin expression

(2011) Young-Sun Kim et al.   BIOCHEMICAL PHARMACOLOGY

Importance of cholesterol and oxysterols metabolism in the pharmacology of tamoxifen and other AEBS ligands

(2011) Philippe de Medina et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1)

(2010) Laura R. Pearce et al.   BIOCHEMICAL JOURNAL

Phosphorylated S6K1 is a possible marker for endocrine therapy resistance in hormone receptor-positive breast cancer

(2010) Eun-Kyu Kim et al.   BREAST CANCER RESEARCH AND TREATMENT

Molecular Mechanism and Clinical Implications of Endocrine Therapy Resistance in Breast Cancer

(2010) Grazia Arpino et al.   ONCOLOGY

Tamoxifen and AEBS ligands induced apoptosis and autophagy in breast cancer cells through the stimulation of sterol accumulation

(2009) Philippe de Medina et al.   Autophagy

Nuclear protein 1 induced by ATF4 in response to various stressors acts as a positive regulator on the transcriptional activation of ATF4

(2009) Hyeon-Ok Jin et al.   IUBMB LIFE

Targeting the mTOR Signaling Network for Cancer Therapy

(2009) Funda Meric-Bernstam et al.   JOURNAL OF CLINICAL ONCOLOGY

Crosstalk between the Estrogen Receptor and the HER Tyrosine Kinase Receptor Family: Molecular Mechanism and Clinical Implications for Endocrine Therapy Resistance

(2008) Grazia Arpino et al.   ENDOCRINE REVIEWS

Regulation and localization of ribosomal protein S6 kinase 1 isoforms

(2008) Doyil Kim et al.   GROWTH FACTORS

S6 Kinase 1 Regulates Estrogen Receptor α in Control of Breast Cancer Cell Proliferation

(2008) Rachel L. Yamnik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTORC1 promotes survival through translational control of Mcl-1

(2008) J. R. Mills et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA