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Title
Klotho: a novel biomarker for cancer
Authors
Keywords
Klotho, Cancer, Signaling pathway, Epigenetic
Journal
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
Volume 141, Issue 6, Pages 961-969
Publisher
Springer Nature
Online
2014-08-02
DOI
10.1007/s00432-014-1788-y
References
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- (2008) I Wolf et al. ONCOGENE
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