The Role of TLR and Chemokine in Wear Particle-Induced Aseptic Loosening

Revision joint replacement, wear particles, and macrophage polarization

(2012) Allison J. Rao et al.   Acta Biomaterialia

Inhibition of Titanium Particle-Induced Inflammation by the Proteasome Inhibitor Bortezomib in Murine Macrophage-Like RAW 264.7 Cells

(2012) Xin Mao et al.   INFLAMMATION

Dissecting negative regulation of Toll-like receptor signaling

(2012) Takeshi Kondo et al.   TRENDS IN IMMUNOLOGY

Role of the Toll-like receptor pathway in the recognition of orthopedic implant wear-debris particles

(2011) Jeremy I. Pearl et al.   BIOMATERIALS

Is Monocyte Chemotactic Protein 1 Elevated in Aseptic Loosening of TKA?: A Pilot Study

(2011) Vinod Dasa et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

The potential role of human osteoblasts for periprosthetic osteolysis following exposure to wear particles

(2011) Katrin Lochner   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Toll-like receptors and their adaptors are regulated in macrophages after phagocytosis of lipopolysaccharide-coated titanium particles

(2011) Tomoyuki Hirayama et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Biological responses of human mesenchymal stem cells to titanium wear debris particles

(2011) Hana Haleem-Smith et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Selective inhibition of the MCP-1-CCR2 ligand-receptor axis decreases systemic trafficking of macrophages in the presence of UHMWPE particles

(2011) Emmanuel Gibon et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Review of periprosthetic osteolysis in total joint arthroplasty: An emphasis on host factors and future directions

(2011) Ryan T. Beck et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Continuous Infusion of UHMWPE Particles Induces Increased Bone Macrophages and Osteolysis

(2010) Pei-Gen Ren et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Bacterial Pathogen-associated Molecular Patterns Stimulate Biological Activity of Orthopaedic Wear Particles by Activating Cognate Toll-like Receptors

(2010) Edward M. Greenfield et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Profile of toll-like receptor-positive cells in septic and aseptic loosening of total hip arthroplasty implants

(2010) Jukka Pajarinen et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Surveillance of systemic trafficking of macrophages induced by UHMWPE particles in nude mice by noninvasive imaging

(2010) Pei-Gen Ren et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Effects of orthopedic polymer particles on chemotaxis of macrophages and mesenchymal stem cells

(2010) Zhinong Huang et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Periprosthetic osteolysis: Characterizing the innate immune response to titanium wear-particles

(2010) Christine A. St. Pierre et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Toll-like receptors and innate immunity

(2009) Himanshu Kumar et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The roles of monocytic heat shock protein 60 and Toll-like receptors in the regional inflammation response to wear debris particles

(2009) Hsiao-Nan Hao et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Titanium induced production of chemokines CCL17/TARC and CCL22/MDC in human osteoclasts and osteoblasts

(2009) Dieter Cadosch et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Titanium particles modulate expression of Toll-like receptor proteins

(2009) Jukka Pajarinen et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Toll-like receptors and aseptic loosening of hip endoprosthesis-a potential to respond against danger signals?

(2009) Tuomas Lähdeoja et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Increased Expression of Toll-like Receptors in Aseptic Loose Periprosthetic Tissues and Septic Synovial Membranes Around Total Hip Implants

(2009) Y. TAMAKI et al.   JOURNAL OF RHEUMATOLOGY

Endosomal damage and TLR2 mediated inflammasome activation by alkane particles in the generation of aseptic osteolysis

(2009) Radhashree Maitra et al.   MOLECULAR IMMUNOLOGY

The role of Toll-like receptors in rheumatoid arthritis

(2009) Qi-Quan Huang et al.   Current Rheumatology Reports

Alternative macrophage activation in periprosthetic osteolysis

(2008) P. Edward Purdue   AUTOIMMUNITY

The Interleukin-8 Pathway in Cancer

(2008) D. J.J. Waugh et al.   CLINICAL CANCER RESEARCH

Ultrahigh molecular weight polyethylene wear debris inhibits osteoprogenitor proliferation and differentiationin vitro

(2008) Richard Chiu et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Expression profiling reveals alternative macrophage activation and impaired osteogenesis in periprosthetic osteolysis

(2007) Panagiotis Koulouvaris et al.   JOURNAL OF ORTHOPAEDIC RESEARCH