Toward Engineering Synthetic Microbial Metabolism

Zinc-finger-based artificial transcription factors and their applications

(2009) Takashi Sera   ADVANCED DRUG DELIVERY REVIEWS

Mutagenesis of the Bacterial RNA Polymerase Alpha Subunit for Improvement of Complex Phenotypes

(2009) D. Klein-Marcuschamer et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Constraints-based genome-scale metabolic simulation for systems metabolic engineering

(2009) Jong Myoung Park et al.   BIOTECHNOLOGY ADVANCES

Engineering multigene expression in vitro and in vivo with small terminators for T7 RNA polymerase

(2009) Liping Du et al.   BIOTECHNOLOGY AND BIOENGINEERING

A Synthetic Genetic Edge Detection Program

(2009) Jeffrey J. Tabor et al.   CELL

Frameworks for Programming Biological Function through RNA Parts and Devices

(2009) Maung Nyan Win et al.   CHEMISTRY & BIOLOGY

Modular model-based design for heterologous bioproduction in bacteria

(2009) Thomas E Landrain et al.   CURRENT OPINION IN BIOTECHNOLOGY

Genomics enabled approaches in strain engineering

(2009) Joseph R Warner et al.   CURRENT OPINION IN MICROBIOLOGY

Synthesis of Methyl Halides from Biomass Using Engineered Microbes

(2009) Travis S. Bayer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

You're one in a googol: optimizing genes for protein expression

(2009) M. Welch et al.   Journal of the Royal Society Interface

Designing and encoding models for synthetic biology

(2009) L. Endler et al.   Journal of the Royal Society Interface

Engineering the Salmonella type III secretion system to export spider silk monomers

(2009) Daniel M Widmaier et al.   Molecular Systems Biology

Large-scale identification of genetic design strategies using local search

(2009) Desmond S Lun et al.   Molecular Systems Biology

Spatiotemporal control of cell signalling using a light-switchable protein interaction

(2009) Anselm Levskaya et al.   NATURE

Programming cells by multiplex genome engineering and accelerated evolution

(2009) Harris H. Wang et al.   NATURE

Overpowering the component problem

(2009) Matthew R Bennett et al.   NATURE BIOTECHNOLOGY

Diversity-based, model-guided construction of synthetic gene networks with predicted functions

(2009) Tom Ellis et al.   NATURE BIOTECHNOLOGY

Synthetic protein scaffolds provide modular control over metabolic flux

(2009) John E Dueber et al.   NATURE BIOTECHNOLOGY

Stabilized gene duplication enables long-term selection-free heterologous pathway expression

(2009) Keith E J Tyo et al.   NATURE BIOTECHNOLOGY

Automated design of synthetic ribosome binding sites to control protein expression

(2009) Howard M Salis et al.   NATURE BIOTECHNOLOGY

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

The second wave of synthetic biology: from modules to systems

(2009) Priscilla E. M. Purnick et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

FMM: a web server for metabolic pathway reconstruction and comparative analysis

(2009) Chih-Hung Chou et al.   NUCLEIC ACIDS RESEARCH

Writing DNA with GenoCADTM

(2009) M. J. Czar et al.   NUCLEIC ACIDS RESEARCH

Golden Gate Shuffling: A One-Pot DNA Shuffling Method Based on Type IIs Restriction Enzymes

(2009) Carola Engler et al.   PLoS One

Circular Polymerase Extension Cloning of Complex Gene Libraries and Pathways

(2009) Jiayuan Quan et al.   PLoS One

A family of thermostable fungal cellulases created by structure-guided recombination

(2009) P. Heinzelman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic Gene Networks That Count

(2009) A. E. Friedland et al.   SCIENCE

Measuring the activity of BioBrick promoters using an in vivo reference standard

(2009) Jason R Kelly et al.   Journal of Biological Engineering

Synthetic Biology for Synthetic Chemistry

(2008) Jay D. Keasling   ACS Chemical Biology

Application of Functional Genomics to Pathway Optimization for Increased Isoprenoid Production

(2008) L. Kizer et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Production of Glucaric Acid from a Synthetic Pathway in Recombinant Escherichia coli

(2008) T. S. Moon et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Computational design of synthetic gene circuits with composable parts

(2008) M.A. Marchisio et al.   BIOINFORMATICS

Strategies for systems-level metabolic engineering

(2008) Tae Yong Kim et al.   Biotechnology Journal

Networking Opportunities for Bacteria

(2008) Daniel J. Dwyer et al.   CELL

Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences

(2008) Arjun Raj et al.   CELL

Redesigning Enzymes Based on Adaptive Evolution for Optimal Function in Synthetic Metabolic Pathways

(2008) Yasuo Yoshikuni et al.   CHEMISTRY & BIOLOGY

De novo biosynthetic pathways: rational design of microbial chemical factories

(2008) Kristala L Jones Prather et al.   CURRENT OPINION IN BIOTECHNOLOGY

Engineering the spatial organization of metabolic enzymes: mimicking nature's synergy

(2008) Robert J Conrado et al.   CURRENT OPINION IN BIOTECHNOLOGY

Importance of systems biology in engineering microbes for biofuel production

(2008) Aindrila Mukhopadhyay et al.   CURRENT OPINION IN BIOTECHNOLOGY

Combinatorial engineering of microbes for optimizing cellular phenotype

(2008) Christine Nicole S Santos et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Toward scalable parts families for predictable design of biological circuits

(2008) Julius B Lucks et al.   CURRENT OPINION IN MICROBIOLOGY

Setting the standard in synthetic biology

(2008) Adam Arkin   NATURE BIOTECHNOLOGY

Refinement and standardization of synthetic biological parts and devices

(2008) Barry Canton et al.   NATURE BIOTECHNOLOGY

Production of benzylisoquinoline alkaloids in Saccharomyces cerevisiae

(2008) Kristy M Hawkins et al.   Nature Chemical Biology

DNA assembler, an in vivo genetic method for rapid construction of biochemical pathways

(2008) Zengyi Shao et al.   NUCLEIC ACIDS RESEARCH

Design and Construction of a Double Inversion Recombination Switch for Heritable Sequential Genetic Memory

(2008) Timothy S. Ham et al.   PLoS One

One-step assembly in yeast of 25 overlapping DNA fragments to form a complete synthetic Mycoplasma genitalium genome

(2008) D. G. Gibson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expanding metabolism for biosynthesis of nonnatural alcohols

(2008) K. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complete Chemical Synthesis, Assembly, and Cloning of a Mycoplasma genitalium Genome

(2008) D. G. Gibson et al.   SCIENCE

Application of systems biology for bioprocess development

(2008) Jin Hwan Park et al.   TRENDS IN BIOTECHNOLOGY

Engineering microbial consortia: a new frontier in synthetic biology

(2008) Katie Brenner et al.   TRENDS IN BIOTECHNOLOGY

Genetic design: rising above the sequence

(2008) Jonathan A. Goler et al.   TRENDS IN BIOTECHNOLOGY

Gene synthesis demystified

(2008) Michael J. Czar et al.   TRENDS IN BIOTECHNOLOGY

Engineering BioBrick vectors from BioBrick parts

(2008) Reshma P Shetty et al.   Journal of Biological Engineering