Article
Environmental Sciences
Marcelino Benvindo-Souza, Daiany Folador Sotero, Cirley Gomes Araujo dos Santos, Rhayane Alves de Assis, Rinneu Elias Borges, Lia Raquel de Souza Santos, Daniela de Melo e Silva
Summary: Pollution from mining activities can cause genotoxic damage to bats, particularly in species like Carollia perspicillata and Glossophaga soricina. High levels of elements such as Mn, Cr, Pb, and Zn were found in water samples from the mining area. The study suggests that bats in mining areas are susceptible to increased DNA damage, similar to what has been observed in other species.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Environmental Sciences
Vehbi Atahan Togay, Gulcin Yavuz Turel, Dilek Asci celik, Meltem ozgocmen, Eda Evgen Tuluceoglu, Ismail Sen, Yusuf Ayvaz
Summary: This study found that cyprodinil and thiacloprid exposure can lead to increased DNA damage risk in zebrafish, as demonstrated by comet assay. These pesticides were identified as genotoxic agents that require further investigation.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Multidisciplinary Sciences
Mirko Marino, Letizia Gigliotti, Peter Moller, Patrizia Riso, Marisa Porrini, Cristian Del Bo
Summary: The comet assay is used to assess DNA damage in tissues and biological samples. This study found that storage time had varying effects on DNA damage levels in PBMCs and WB samples, with significant increases observed in WB samples stored for over 6 months. WB samples showed higher levels of DNA damage compared to PBMCs.
SCIENTIFIC REPORTS
(2021)
Article
Environmental Sciences
Rafael Valencia-Quintana, Mirta Milic, Stefano Bonassi, Maria Antonieta Ochoa-Ocana, Victoria Campos-Pena, Maria Guadalupe Tenorio-Arvide, Guillermo Alejandro Perez-Flores, Juana Sanchez-Alarcon
Summary: This study evaluated the effect of pesticides on genetic damage to agricultural workers in Los Reyes, Michoacan, Mexico. The results showed that pesticide use poses a risk of genetic damage to agricultural workers, but measures can be taken to reduce this risk.
Article
Pharmacology & Pharmacy
Jorid B. Sorlia, Alexander C. O. Jensen, Alicja Mortensen, Jozef Szarek, Claudia A. T. Gutierrez, Lucas Givelet, Katrin Loeschner, Charis Loizides, Iosif Hafez, George Biskos, Ulla Vogel, Niels Hadrup
Summary: By conducting nose-only inhalation tests on mice, we found that the air concentration of molybdenum disulphide particles has no observed adverse effect on body weight gain and genotoxicity below 13mg/m³, while the effects on respiratory function suggest this level as the lowest observed adverse effect concentration.
Review
Environmental Sciences
Aryelle Canedo, Thiago Lopes Rocha
Summary: Zebrafish have become a popular model for assessing the genotoxicity of pollutants due to their orthologous genes and involvement in repair pathways. Comet assay is the main technique used in these studies, but standardization is needed for better interpretation and comparisons. Understanding repair mechanisms in zebrafish subjected to DNA damage is essential for further research on genotoxic effects caused by pollutants.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Felipe de Araujo Nascimento, Daniela de Melo e Silva, Thays Millena Alves Pedroso, Jheneffer Sonara Aguiar Ramos, Michelle Rocha Parise
Summary: Occupational exposure to pesticides in farmers results in significant DNA damage, showing a notable impact and variability in the studies. Smokers who are occupationally exposed to pesticides have slightly reduced DNA damage compared to non-smokers, indicating some genetic toxicity. The study demonstrates a higher risk of occupationally exposed rural workers developing related diseases due to the genotoxic effect of pesticides.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Environmental Sciences
Marcelino Benvindo-Souza, Akemi Vieira Hosokawa, Cirley Gomes Araujo dos Santos, Rhayane Alves de Assis, Thays Millena Alves Pedroso, Rinneu Elias Borges, Susi Missel Pacheco, Lia Raquel de Souza Santos, Daniela de Melo e Silva
Summary: Habitat loss and fragmentation pose significant threats to biodiversity. The use of bioindicators can provide insight into the health of the environment. A study conducted in agricultural areas found higher genotoxic damage in bats compared to a control area.
ENVIRONMENTAL POLLUTION
(2022)
Article
Chemistry, Multidisciplinary
Monica Reynoso-Silva, Carlos Alvarez-Moya, Rafael Ramirez-Velasco, Alexis Gerardo Samano-Leon, Erandi Arvizu-Hernandez, Hugo Castaneda-Vasquez, Mario Alberto Ruiz-Lopez
Summary: A new approach for genetic damage assessment using the comet assay is proposed based on specific parameters which can improve the detection of genetic damage associated with certain genotoxic agents. The study shows significant differences in tail length and migration groups among genotoxic agents, indicating a specific chemical interaction on the DNA.
APPLIED SCIENCES-BASEL
(2021)
Article
Environmental Sciences
Muhammad Khisroon, Nazia Hassan, Ajmal Khan, Javeed Farooqi
Summary: The study evaluated the genotoxic effect of endosulfan on grass carp blood, finding that exposure to this pesticide led to significant DNA damage in a time- and dose-dependent manner. As endosulfan demonstrated severe genotoxic effects on Ctenopharyngodon idella, the study recommends that its use be controlled and monitored by government authorities to prevent further harm to ecosystems.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Toxicology
Ezgi Eyluel Bankoglu, Carolin Schuele, Helga Stopper
Summary: The comet assay is widely used in basic research, genotoxicity testing, and human biomonitoring. The study found that DNA damage exceeding 20-30% tail DNA caused more than 50% of cells to die, with etoposide causing slightly more cell death than H2O2 or MMS. Cells showed some repair capacity for DNA damage within a few hours after substance removal.
ARCHIVES OF TOXICOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Galina N. Chelomina, Sergey P. Kukla, Viktor P. Chelomin, Pham N. Doanh
Summary: Parasite infection can lead to DNA damage, potentially involving oxidative stress and cancer development; these research findings are important for understanding the pathogenesis mechanisms of parasitic diseases.
Article
Nutrition & Dietetics
Agnes Draxler, Bernhard Franzke, Johannes T. Cortolezis, Nicola A. Gillies, Sandra Unterberger, Rudolf Aschauer, Patrick A. Zoehrer, Laura Bragagna, Julia Kodnar, Eva-Maria Strasser, Oliver Neubauer, Pankaja Sharma, Sarah M. Mitchell, Nina Zeng, Farha Ramzan, Randall F. D'Souza, Scott O. Knowles, Nicole C. Roy, Anders M. Sjoedin, Cameron J. Mitchell, Amber M. Milan, Barbara Wessner, David Cameron-Smith, Karl-Heinz Wagner
Summary: The study found that increasing protein intake to more than 20% of the total energy intake in community-dwelling seniors in Austria and New Zealand did not increase measures of DNA damage, change glutathione status or elevate plasma CRP levels.
Article
Public, Environmental & Occupational Health
Martin Roursgaard, Monika Hezareh Rothmann, Juliane Schulte, Ioanna Karadimou, Elena Marinelli, Peter Moller
Summary: This study investigated the extraction of nanoplastic particles from food containers and found that these nanoparticles can cause genotoxicity in cell cultures, while their cytotoxic effects were limited.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Food Science & Technology
Merve Bacanli, Ozgur Esim, Hakan Erdogan, Meral Sarper, Onur Erdem, Yalcin Ozkan
Summary: This study evaluated the cytotoxicity and genotoxicity of paclitaxel nanoencapsulated with PLGA in human neuroblastoma cells. Results showed that PLGA nanoparticles can be considered as a biocompatible carrier system for drug delivery and might be a promising agent against neuroblastoma.
FOOD AND CHEMICAL TOXICOLOGY
(2021)
Article
Polymer Science
Akshay Modi, Jayesh Bellare
Article
Nanoscience & Nanotechnology
Deepak Gupta, Atul Kumar Singh, Ashwin Dravid, Jayesh Bellare
ACS APPLIED MATERIALS & INTERFACES
(2019)
Article
Engineering, Biomedical
Ajay Suryavanshi, Kunal Khanna, K. R. Sindhu, Jayesh Bellare, Rohit Srivastava
BIOMEDICAL MATERIALS
(2019)
Article
Biochemistry & Molecular Biology
Akshay Modi, Jayesh Bellare
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2019)
Article
Materials Science, Biomaterials
Deepak Gupta, Atul Kumar Singh, Neelakshi Kar, Ashwin Dravid, Jayesh Bellare
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2019)
Article
Biology
Sanjay Kumar Kureel, Pankaj Mogha, Akshada Khadpekar, Vardhman Kumar, Rohit Joshi, Siddhartha Das, Jayesh Bellare, Abhijit Majumde
Article
Endocrinology & Metabolism
Subhashis Pal, Konica Porwal, Kunal Khanna, Manoj Kumar Gautam, Mohd Yaseen Malik, Mamunur Rashid, R. John Macleod, Muhammad Wahajuddin, Venkitanarayanan Parameswaran, Jayesh R. Bellare, Naibedya Chattopadhyay
Article
Integrative & Complementary Medicine
Abhirup Basu, Mayur K. Temgire, Akkihebbal K. Suresh, Jayesh R. Bellare
Article
Plant Sciences
Snehasis Biswas, Rohit Dhumal, Nilakash Selkar, Sharad Bhagat, Mukesh Chawda, Kapil Thakur, Ramacharya Gudi, Geeta Vanage, Jayesh Bellare
JOURNAL OF ETHNOPHARMACOLOGY
(2020)
Article
Biochemistry & Molecular Biology
Prissana Robkhob, Sougata Ghosh, Jayesh Bellare, Dhiraj Jamdade, I-Ming Tang, Sirikanjana Thongmee
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2020)
Article
Engineering, Chemical
Preety Kumari, Akshay Modi, Jayesh Bellare
SEPARATION AND PURIFICATION TECHNOLOGY
(2020)
Article
Multidisciplinary Sciences
Siddhartha Das, Kanchan Dholam, Sandeep Gurav, Kiran Bendale, Arvind Ingle, Bhabani Mohanty, Pradip Chaudhari, Jayesh R. Bellare
SCIENTIFIC REPORTS
(2019)
Article
Engineering, Environmental
Akshay Modi, Jayesh Bellare
JOURNAL OF WATER PROCESS ENGINEERING
(2020)
Article
Engineering, Environmental
Akshay Modi, Jayesh Bellare
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2019)
Article
Pharmacology & Pharmacy
Dhiraj A. Jamdade, Dishantsingh Rajpali, Komal A. Joshi, Rohini Kitture, Anuja S. Kulkarni, Vaishali S. Shinde, Jayesh Bellare, Kaushik R. Babiya, Sougata Ghosh
ADVANCES IN PHARMACOLOGICAL SCIENCES
(2019)
