Article
Nanoscience & Nanotechnology
Carole Seidel, Vadim Zhernovkov, Hilary Cassidy, Boris Kholodenko, David Matallanas, Frederic Cosnier, Laurent Gate
Summary: Inhalation of multi-walled carbon nanotubes (MWCNTs) induces lung inflammation, with different morphologies of CNTs showing varying toxicological effects. Long-term exposure may result in persistent adverse effects.
Article
Chemistry, Multidisciplinary
Sandeep Keshavan, Fernando Torres Andon, Audrey Gallud, Wei Chen, Knut Reinert, Lang Tran, Bengt Fadeel
Summary: Engineered nanomaterials have potential risks to human health, and studies have shown that multi-walled carbon nanotubes (MWCNTs) significantly affect chemokine signaling pathways. Evaluating sub-lethal concentrations of nanomaterials in relevant target cells is crucial.
Article
Chemistry, Inorganic & Nuclear
Mona Hamelian, Kambiz Varmira, Hojat Veisi
Summary: The present study successfully synthesized a novel magnetic nanocatalyst that can efficiently reduce organic dyes. The catalyst was thoroughly characterized using various techniques, and it was found that the catalyst can reduce different organic dyes in the presence of NaBH4 at room temperature. UV-Vis spectroscopy revealed that the reduction reaction follows pseudo-first-order kinetics. Additionally, the synthesized catalyst can be collected using a magnet and reused multiple times.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
Article
Chemistry, Analytical
Saddam Weheabby, Zhenyn Wu, Ammar Al -Hamry, Igor A. Pasti, Adiraju Anurag, Doreen Dentel, Christoph Tegenkamp, Olfa Kanoun
Summary: This study demonstrates the voltammetric sensing of paracetamol using silver nanoparticles and carboxylated multi-walled carbon nanotubes on a screen-printed carbon electrode. The sensor shows effective sensing potential with a low detection limit under optimal conditions. Experimental and computational studies were conducted to support the findings. The proposed method shows promising applications for determining paracetamol in environmental and pharmaceutical samples.
MICROCHEMICAL JOURNAL
(2023)
Article
Multidisciplinary Sciences
Selma Ekinci, Zulfiye Ilter, Selami Ercan, Ercan Cinar, Resit Cakmak
Summary: In this study, new, efficient, eco-friendly and magnetically separable nanoadsorbents, MNPs-G1-Mu and MNPsG2-Mu, were successfully prepared and used for rapid removal of lead (II) from aqueous medium. The maximum adsorption capacities of both adsorbents were compared, showing good performance. Additionally, antimicrobial activities of the nanoparticles were examined and exhibited positive results against various microorganisms.
Article
Plant Sciences
Pallavi Dhiman, Nitika Rajora, Shubham Bhardwaj, Sreeja S. Sudhakaran, Amit Kumar, Gaurav Raturi, Koushik Chakraborty, Om Prakash Gupta, B. N. Devanna, Durgesh Kumar Tripathi, Rupesh Deshmukh
Summary: This review explores the role of silicon in alleviating salt stress in plants, including its impact on physiological and biochemical processes, the molecular mechanisms behind its beneficial effects, and its interaction with plant responses at transcriptomics and proteomics levels.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Silvia Aidee Solorio-Rodriguez, Andrew Williams, Sarah Sos Poulsen, Kristina Bram Knudsen, Keld Alstrup Jensen, Per Axel Clausen, Pernille Hogh Danielsen, Hakan Wallin, Ulla Vogel, Sabina Halappanavar
Summary: This study aimed to determine the influence of single or multi-walled structures and surface functionalization on pulmonary toxicity of carbon nanotubes (CNTs) and to identify the underlying mechanisms. Mice were exposed to different doses of SWCNTs or MWCNTs, and inflammation and DNA damage were assessed. Transcriptomics analysis showed similar responses across all CNTs, with inflammation, cellular stress, metabolism, and DNA damage responses being affected. One pristine SWCNT was found to be the most potent and potentially fibrogenic, warranting further toxicity testing.
Article
Chemistry, Physical
Giovanni Scala, Mathilde N. Delaval, Sourav P. Mukherjee, Antonio Federico, Timur O. Khaliullin, Naveena Yanamala, Liliya M. Fatkhutdinova, Elena R. Kisin, Dario Greco, Bengt Fadeel, Anna A. Shvedova
Summary: The study revealed that MWCNTs exert epigenetic effects in the lungs, potentially driving subsequent gene expression changes. Muscle contraction, immune system/inflammation, and extracellular matrix pathways were the most affected pathways.
Article
Pharmacology & Pharmacy
Rehab A. Alshammari, Fadilah S. Aleanizy, Amal Aldarwesh, Fulwah Y. Alqahtani, Wael A. Mahdi, Bushra Alquadeib, Qamraa H. Alqahtani, Nazrul Haq, Faiyaz Shakeel, Hosam G. Abdelhady, Ibrahim A. Alsarra
Summary: This study developed RBX nanoparticles using PAMAM dendrimers for the treatment of diabetic retinopathy, providing a safe and effective method for RBX administration. The drug loading efficiency and in vitro release of the RBX:PAMAM dendrimer complexes were evaluated, and the 5:1 complex showed the highest loading efficiency and drug release. The nanoformulation improved the therapeutic outcomes of anti-VEGF therapy and the bioavailability of RBX for preventing vision loss in patients with diabetic retinopathy.
Article
Multidisciplinary Sciences
Jae-Won Lee, Joon Young Cho, Mi Jeong Kim, Jung Hoon Kim, Jong Hwan Park, Seung Yol Jeong, Seon Hee Seo, Geon-Woong Lee, Hee Jin Jeong, Joong Tark Han
Summary: The study reports an elastic composite film composed of silver nanoparticles embedded with single-walled carbon nanotubes synthesized in aqueous solutions, with efficient sintering of conductive fillers achieved through short-duration irradiation. The stretchable electrodes and strain sensors fabricated show high conductivity and stability, successfully applied to detecting finger motions in practical demonstrations.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Multidisciplinary
Shankar S. Narwade, Shivsharan M. Mali, Bhaskar R. Sathe
Summary: This study presents a highly efficient and inexpensive metal-free electrocatalyst for hydrogen evolution reaction (HER) and oxygen evolution reaction (OER). The ethylene diamine decoration on multi-walled carbon nanotubes provides nitrogen-rich nanomaterials, offering a promising approach for replacing fossil fuels.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Engineering, Environmental
Ronggui Tang, Dong Zhu, Yongming Luo, Defu He, Haibo Zhang, Ei-Naggar Ali, Kumuduni Niroshika Palansooriya, Keyi Chen, Yan Yan, Xinghang Lu, Minshen Ying, Tao Sun, Yuntao Cao, Zhihan Diao, Yuxin Zhang, Yichen Lian, Scott X. Chang, Yanjiang Cai
Summary: This study investigated the responses of earthworms to polystyrene nanoplastics (NPs) at a relatively low concentration in contaminated soil. The results showed that NPs accumulated in the earthworms' intestinal tissues and caused damage to their digestive and immune systems. Furthermore, the NPs reduced the diversity and species richness of the gut microorganisms. The study suggests that NPs pollution poses significant environmental toxicity risks for soil fauna.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Materials Science, Characterization & Testing
Hengqian Jin, Shufei Wei, Xinping Zhang, Huarong Nie, Aihua He
Summary: This study successfully fabricated novel hydrophilic multi-heterostructure composites (Mag@J/MWCNT), which combined nanostructured Fe3O4 covered snowman-like Janus nano-particles (Mag@J) with MWCNTs to enhance microwave absorption. The composites demonstrated good hydrophilicity, low reflection loss (RL), strong absorption intensity (RL = -38.98 dB), wide bandwidth (6.04-8.23 GHz), and low thickness (3.5 mm). The excellent microwave absorption properties were attributed to the strong dielectric loss, magnetic loss, and good impedance matching of different components, as well as multiple reflection absorption of microwave in the Janus particle's hollow sphere.
Article
Materials Science, Multidisciplinary
Hefeng Li, Hongtao Wang, Cong Liu, Xianhua Huan, Jingxuan Dong, Wusheng Li, Ke Xu, Hongbo Geng, Xiaodong Guo, Xiaolong Jia, Xiaoping Yang
Summary: The correlationship between the molecular weight of surface-grafted polyglycidyl methacrylate (PGMA) and the dispersion state of PGMA-grafted MWCNTs was systematically investigated in this study. The molecular weight of surface-grafted PGMA was measured using X-ray photoelectron spectroscope (XPS) and thermos-gravimetric analyzer (TGA). The results showed that the dispersion state of MWCNTs-PGMA in PMMA solution was enhanced with the increase in the molecular weight of grafted PGMA. The EP composites exhibited the highest enhancement in mechanical properties when using MWCNTs-PGMA-3 with the largest PGMA molecular weight as the reinforcement.
JOURNAL OF MATERIALS SCIENCE
(2022)
Article
Engineering, Environmental
Wen-Juan Zeng, Chuang Li, Yue Feng, Shu-Huan Zeng, Bing-Xin Fu, Xiao-Liang Zhang
Summary: Composite membranes of GO/CNTs with fine hierarchical nanostructure were successfully fabricated by intercalation of MWCNTs-COOH into GO nanosheets, showing efficient organic wastewater treatment with high rejection and permeated flux towards methylene blue dye solutions. The membranes exhibited nearly 10-fold water permeated flux improvement compared to pristine GO membranes, with electrostatic interaction and size exclusion effects contributing to the efficient separation properties against different types of dyes and organic molecules.
JOURNAL OF WATER PROCESS ENGINEERING
(2021)
Article
Medicine, Legal
Kinga Kadziola-Dlugolecka, Oliwia Fraczak, Beata Tkacz-Szczesna, Ilona Kijewska, Radoslaw Wilczek, Krzysztof Makowski, Piotr Komorowski, Robert Bachlinski, Anna Trynda, Bogdan Walkowiak
Summary: This publication presents analytical data for four psychoactive substances, including methods for their synthesis and confirmation such as ESI-MS, GC-EI-MS, GC-FID, HPLC, Raman spectroscopy, and H-1 NMR. It also discusses characteristic fragmentation patterns for cannabinoids and the development of HPLC methods for qualitative and quantitative determination of all synthesized compounds. Additionally, it utilizes RAMAN and GC-FID as analytical tools for compound identification in stability tests.
AUSTRALIAN JOURNAL OF FORENSIC SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Agnieszka M. Kolodziejczyk, Magdalena Kucinska, Aleksandra Jakubowska, Paulina Sokolowska, Marcin Rosowski, Beata Tkacz-Szczesna, Piotr Komorowski, Krzysztof Makowski, Bogdan Walkowiak
JOURNAL OF MOLECULAR RECOGNITION
(2020)
Review
Biochemistry & Molecular Biology
Kamila Bialkowska, Piotr Komorowski, Maria Bryszewska, Katarzyna Milowska
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Optics
Justyna Anna Adamczyk, Karolina Zielonka, Sylwia Kotarba, Jakub Saramak, Ireneusz Glowacki, Michal Rachwalski, Adam Marek Pieczonka
Summary: The photoluminescence properties and self-organizing ability of a series of salicylaldehyde azines substituted with alkoxy chains were investigated in thin solid layers prepared using various techniques. The electronic properties of the compounds were theoretically calculated using density functional theory, and inkjet inks suitable for OLEDs were successfully developed and printed on smooth fluorescent layers.
JOURNAL OF LUMINESCENCE
(2021)
Article
Materials Science, Multidisciplinary
Malgorzata Siatkowska, Paulina Sokolowska, Kamila Bialkowska, Aleksandra Zimon, Magdalena Grala, Marcin Rosowski, Kinga Kadziola-Dlugolecka, Piotr Komorowski, Krzysztof Makowski, Daniel Reda, Bogdan Walkowiak
Summary: Diamond and diamond-like materials possess great potential in biomedical applications, but the toxicity and biocompatibility of different forms of diamond particles, especially at nano and micro levels, need to be carefully studied and monitored to ensure safe use in specific biomedical applications.
DIAMOND AND RELATED MATERIALS
(2021)
Article
Biochemistry & Molecular Biology
Kamila Bialkowska, Katarzyna Milowska, Sylwia Michlewska, Paulina Sokolowska, Piotr Komorowski, Tania Lozano-Cruz, Rafael Gomez-Ramirez, Francisco Javier de la Mata, Maria Bryszewska
Summary: The study investigated the potential of carbosilane dendrimers as carriers for siRNA in gene therapy, focusing on CBD-1 and CBD-2. Both dendrimers were able to complex with siRNA and transport it into cells, with differences observed in their cytotoxicity profiles. This research highlights the importance of dendrimers in enhancing cellular uptake and efficiency of siRNA delivery for gene therapy applications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Microbiology
T. Ploszaj, M. Brauncajs, M. Traczyk-Borszynska, T. Matyjas, L. Pomorski, T. Wasiak, M. Borowiec
Summary: This study analyzed the microflora of gallstones, identified various bacterial components, and determined the types of gallstones. Potentially harmful microorganisms that could lead to post-surgery complications were found in some patients.
ARCHIVES OF MICROBIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Paulina Sokolowska, Malgorzata Siatkowska, Marta Jozwiak-Bebenista, Piotr Komorowski, Marta Koptas, Edward Kowalczyk, Anna Wiktorowska-Owczarek
Summary: Diclofenac, a nonsteroidal anti-inflammatory drug, has been evaluated for its effects on the unfolded protein response (UPR) pathways in endothelial cells. The study found that diclofenac can restore ER homeostasis by diminishing the UPR.
Article
Chemistry, Multidisciplinary
Krzysztof Andrzejewski, Marcin Elgalal, Piotr Komorowski, Jan Poszepczynski, Bozena Rokita, Marcin Domzalski
Summary: The study aimed to develop a Fast-Track-Protocol for creating 3D anatomical models to shape surgical plates for treating complex pelvic fractures. Through the low-budget approach using open-source software and 3D printers, a hospital-based multidisciplinary team successfully conducted pre-surgical planning and treated pelvic fractures with improved surgical techniques and shorter operative times.
APPLIED SCIENCES-BASEL
(2022)
Article
Cell Biology
Kamila Bialkowska, Piotr Komorowski, Rafael Gomez-Ramirez, Francisco Javier de la Mata, Maria Bryszewska, Katarzyna Milowska
Summary: Cationic dendrimers have been found to be effective carriers for delivering siRNA into cells and protecting nucleic acids. In 3D cell cultures, CBD-2 exhibits higher cytotoxicity compared to CBD-1, while the opposite is observed in 2D cultures. Attaching siRNA to a dendrimer molecule does not increase cellular toxicity. CBD-2 shows higher efficiency in transporting siRNAs compared to CBD-1.
Article
Pharmacology & Pharmacy
Marta Jozwiak-Bebenista, Paulina Sokolowska, Malgorzata Siatkowska, Cecilia Analia Panek, Piotr Komorowski, Edward Kowalczyk, Anna Wiktorowska-Owczarek
Summary: The research investigated whether UPR signaling pathway activation in astrocytes may serve as a novel target for antidepressant drugs, and found that S-ketamine may have therapeutic effects.
Article
Endocrinology & Metabolism
Tadeusz Strozik, Krystyna Jedrychowska-Danska, Alicja Zamerska, Ewelina Stoczynska-Fidelus, Tomasz Wasiak
Summary: This study investigated the association between genetic variations in the UPS gene cluster and type 1 diabetes in the Polish population. The results showed that certain polymorphisms had a protective effect on T1DM, while rare alleles increased the risk. The study suggests that these proteasome gene polymorphisms could be potential markers for T1DM susceptibility in the Polish population.
CURRENT DIABETES REVIEWS
(2023)
Article
Medicine, General & Internal
Krzysztof Andrzejewski, Marcin Domzalski, Piotr Komorowski, Jan Poszepczynski, Bozena Rokita, Marcin Elgalal
Summary: This study demonstrated the use of open-source medical image reconstruction software and low-cost 3D anatomical models in pre-surgical planning of RHA. The results showed that this method is effective in determining the center of rotation and positioning acetabular cups in RHA.
Article
Biotechnology & Applied Microbiology
Krzysztof Makowski, Martyna Leszczewicz, Natalia Broncel, Lidia Lipinska-Zubrycka, Adrian Glebski, Piotr Komorowski, Bogdan Walkowiak
Summary: The study isolated 40 bacterial strains with cellulolytic activity, most of which were Gram-positive rod-shaped bacteria capable of growth at a minimum of 50 degrees C. Several strains exhibited significant carboxymethyl cellulase (CMCase) activity and hydrolysis capacities, with some identified as Bacillus licheniformis and Paenibacillus lactis. These thermotolerant strains offer potential as a source of new thermostable cellulases for various applications in circular bioeconomy.
FOOD TECHNOLOGY AND BIOTECHNOLOGY
(2021)