The MST4–MOB4 complex disrupts the MST1–MOB1 complex in the Hippo–YAP pathway and plays a pro-oncogenic role in pancreatic cancer

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

(2017) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

Stiehopus japonieus acidic mucopolysaccharide inhibits the proliferation of pancreatic cancer SW1990 cells through Hippo-YAP pathway

(2017) Xiaoyu Li et al.   Oncotarget

SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK

(2017) Sung Jun Bae et al.   eLife

KRAS/NF-κB/YY1/miR-489 Signaling Axis Controls Pancreatic Cancer Metastasis

(2016) Peng Yuan et al.   CANCER RESEARCH

STRIPAK complexes in cell signaling and cancer

(2016) Z Shi et al.   ONCOGENE

MST3 promotes proliferation and tumorigenicity through the VAV2/Rac1 signal axis in breast cancer

(2016) Chien-Yu Cho et al.   Oncotarget

Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer

(2015) Fa-Xing Yu et al.   CELL

Structural basis for Mob1-dependent activation of the core Mst–Lats kinase cascade in Hippo signaling

(2015) Lisheng Ni et al.   GENES & DEVELOPMENT

MST kinases in development and disease

(2015) Barry J. Thompson et al.   JOURNAL OF CELL BIOLOGY

YAP overexpression promotes the epithelial-mesenchymal transition and chemoresistance in pancreatic cancer cells

(2015) YANLI YUAN et al.   Molecular Medicine Reports

The kinase MST4 limits inflammatory responses through direct phosphorylation of the adaptor TRAF6

(2015) Shi Jiao et al.   NATURE IMMUNOLOGY

A Peptide Mimicking VGLL4 Function Acts as a YAP Antagonist Therapy against Gastric Cancer

(2014) Shi Jiao et al.   CANCER CELL

hMOB3 Modulates MST1 Apoptotic Signaling and Supports Tumor Growth in Glioblastoma Multiforme

(2014) F. Tang et al.   CANCER RESEARCH

STRIPAK components determine mode of cancer cell migration and metastasis

(2014) Chris D. Madsen et al.   NATURE CELL BIOLOGY

STRIPAK complexes: Structure, biological function, and involvement in human diseases

(2013) Juyeon Hwang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Activation of the Yeast Hippo Pathway by Phosphorylation-Dependent Assembly of Signaling Complexes

(2013) J. M. Rock et al.   SCIENCE

Protein Interaction Network of the Mammalian Hippo Pathway Reveals Mechanisms of Kinase-Phosphatase Interactions

(2013) A. L. Couzens et al.   Science Signaling

Structure of the MST4 in Complex with MO25 Provides Insights into Its Activation Mechanism

(2013) Zhubing Shi et al.   STRUCTURE

Structural Mechanism of CCM3 Heterodimerization with GCKIII Kinases

(2013) Meng Zhang et al.   STRUCTURE

Rap2A links intestinal cell polarity to brush border formation

(2012) Martijn Gloerich et al.   NATURE CELL BIOLOGY

Protein kinases of the Hippo pathway: Regulation and substrates

(2012) Joseph Avruch et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Regulation of the Hippo pathway by cell architecture and mechanical signals

(2012) Molly C. Schroeder et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Protein phosphatase 2a (PP2A) binds within the oligomerization domain of striatin and regulates the phosphorylation and activation of the mammalian Ste20-Like kinase Mst3

(2011) Johnthan Gordon et al.   BMC BIOCHEMISTRY

Structure-Function Analysis of Core STRIPAK Proteins

(2011) Michelle J. Kean et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation

(2010) M. Fidalgo et al.   JOURNAL OF CELL SCIENCE

Combined Functional Genomic and Proteomic Approaches Identify a PP2A Complex as a Negative Regulator of Hippo Signaling

(2010) Paulo S. Ribeiro et al.   MOLECULAR CELL

Mst1 Is an Interacting Protein that Mediates PHLPPs' Induced Apoptosis

(2010) Meng Qiao et al.   MOLECULAR CELL

Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression

(2010) H. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mst4 and Ezrin Induce Brush Borders Downstream of the Lkb1/Strad/Mo25 Polarization Complex

(2009) Jean Paul ten Klooster et al.   DEVELOPMENTAL CELL

MOBKL1A/MOBKL1B Phosphorylation by MST1 and MST2 Inhibits Cell Proliferation

(2008) Maria Praskova et al.   CURRENT BIOLOGY

The Hippo–YAP pathway: new connections between regulation of organ size and cancer

(2008) Bin Zhao et al.   CURRENT OPINION IN CELL BIOLOGY

A PP2A Phosphatase High Density Interaction Network Identifies a Novel Striatin-interacting Phosphatase and Kinase Complex Linked to the Cerebral Cavernous Malformation 3 (CCM3) Protein

(2008) Marilyn Goudreault et al.   MOLECULAR & CELLULAR PROTEOMICS