Toll-like Receptor 4-mediated Endoplasmic Reticulum Stress in Intestinal Crypts Induces Necrotizing Enterocolitis

Reciprocal Expression and Signaling of TLR4 and TLR9 in the Pathogenesis and Treatment of Necrotizing Enterocolitis

(2014) S. C. Gribar et al.   JOURNAL OF IMMUNOLOGY

The Intestinal Crypt, A Prototype Stem Cell Compartment

(2013) Hans Clevers   CELL

Small intestinal stem cells

(2013) Stephanie L. King et al.   CURRENT OPINION IN GASTROENTEROLOGY

The Unfolded Protein Response and Chemical Chaperones Reduce Protein Misfolding and Colitis in Mice

(2013) Stewart Siyan Cao et al.   GASTROENTEROLOGY

A Critical Role for TLR4 Induction of Autophagy in the Regulation of Enterocyte Migration and the Pathogenesis of Necrotizing Enterocolitis

(2013) M. D. Neal et al.   JOURNAL OF IMMUNOLOGY

The unfolded protein response and gastrointestinal disease

(2013) Arthur Kaser et al.   Seminars in Immunopathology

ER Stress Causes Rapid Loss of Intestinal Epithelial Stemness through Activation of the Unfolded Protein Response

(2013) Jarom Heijmans et al.   Cell Reports

Intestinal Epithelial Toll-Like Receptor 4 Regulates Goblet Cell Development and Is Required for Necrotizing Enterocolitis in Mice

(2012) Chhinder P. Sodhi et al.   GASTROENTEROLOGY

Toll-like Receptor 4 Is Expressed on Intestinal Stem Cells and Regulates Their Proliferation and Apoptosis via the p53 Up-regulated Modulator of Apoptosis

(2012) Matthew D. Neal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intracellular Heat Shock Protein-70 Negatively Regulates TLR4 Signaling in the Newborn Intestinal Epithelium

(2012) A. Afrazi et al.   JOURNAL OF IMMUNOLOGY

Amniotic fluid inhibits Toll-like receptor 4 signaling in the fetal and neonatal intestinal epithelium

(2012) M. Good et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stem cell self-renewal in intestinal crypt

(2011) Benjamin D. Simons et al.   EXPERIMENTAL CELL RESEARCH

LPS-binding Protein Enables Intestinal Epithelial Restitution Despite LPS Exposure

(2011) Juli M. Richter et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Heparin-binding EGF-like growth factor protects intestinal stem cells from injury in a rat model of necrotizing enterocolitis

(2011) Chun-Liang Chen et al.   LABORATORY INVESTIGATION

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

Nucleotide-Binding Oligomerization Domain-2 Inhibits Toll-Like Receptor-4 Signaling in the Intestinal Epithelium

(2010) Ward M. Richardson et al.   GASTROENTEROLOGY

Reduced Apoptosis and Plaque Necrosis in Advanced Atherosclerotic Lesions of Apoe−/− and Ldlr−/− Mice Lacking CHOP

(2009) Edward Thorp et al.   Cell Metabolism

Toll-Like Receptor-4 Inhibits Enterocyte Proliferation via Impaired β-Catenin Signaling in Necrotizing Enterocolitis

(2009) Chhinder P. Sodhi et al.   GASTROENTEROLOGY

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Adaptive suppression of the ATF4–CHOP branch of the unfolded protein response by toll-like receptor signalling

(2009) Connie W. Woo et al.   NATURE CELL BIOLOGY

XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease

(2008) Arthur Kaser et al.   CELL

PUMA Regulates Intestinal Progenitor Cell Radiosensitivity and Gastrointestinal Syndrome

(2008) Wei Qiu et al.   Cell Stem Cell

Chop deletion reduces oxidative stress, improves β cell function, and promotes cell survival in multiple mouse models of diabetes

(2008) Benbo Song et al.   JOURNAL OF CLINICAL INVESTIGATION