Expanding the Proteome of an RNA Virus by Phosphorylation of an Intrinsically Disordered Viral Protein

Targeting the NS5A protein of HCV: An emerging option

(2014) D.G. Cordek et al.   DRUGS OF THE FUTURE

Evolution of a Cell Culture-Derived Genotype 1a Hepatitis C Virus (H77S.2) during Persistent Infection with Chronic Hepatitis in a Chimpanzee

(2014) M. Yi et al.   JOURNAL OF VIROLOGY

Generating NMR chemical shift assignments of intrinsically disordered proteins using carbon-detected NMR methods

(2013) Debashish Sahu et al.   ANALYTICAL BIOCHEMISTRY

Insights into the Complexity and Functionality of Hepatitis C Virus NS5A Phosphorylation

(2013) D. Ross-Thriepland et al.   JOURNAL OF VIROLOGY

Evolutionary conservation of the polyproline II conformation surrounding intrinsically disordered phosphorylation sites

(2013) W. Austin Elam et al.   PROTEIN SCIENCE

The promiscuous binding of the Fyn SH3 domain to a peptide from the NS5A protein

(2012) Jose Manuel Martin-Garcia et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Transient Structure and SH3 Interaction Sites in an Intrinsically Disordered Fragment of the Hepatitis C Virus Protein NS5A

(2012) Sophie Feuerstein et al.   JOURNAL OF MOLECULAR BIOLOGY

A Hepatitis C Virus NS5A Phosphorylation Site That Regulates RNA Replication

(2012) K. L. LeMay et al.   JOURNAL OF VIROLOGY

Annexin A2 Is Involved in the Formation of Hepatitis C Virus Replication Complex on the Lipid Raft

(2012) Vikas Saxena et al.   JOURNAL OF VIROLOGY

C-Src is required for complex formation between the hepatitis C virus-encoded proteins NS5A and NS5B: A prerequisite for replication

(2011) Andreas Pfannkuche et al.   HEPATOLOGY

Small Molecules Targeting Hepatitis C Virus-Encoded NS5A Cause Subcellular Redistribution of Their Target: Insights into Compound Modes of Action

(2011) P. Targett-Adams et al.   JOURNAL OF VIROLOGY

Expanding the proteome: disordered and alternatively folded proteins

(2011) H. Jane Dyson   QUARTERLY REVIEWS OF BIOPHYSICS

Quantifying colocalization by correlation: The Pearson correlation coefficient is superior to the Mander's overlap coefficient

(2010) Jeremy Adler et al.   CYTOMETRY PART A

Identification of a novel phosphorylation site in hepatitis C virus NS5A

(2010) A. Nordle Gilliver et al.   JOURNAL OF GENERAL VIROLOGY

Role of Annexin A2 in the Production of Infectious Hepatitis C Virus Particles

(2010) P. Backes et al.   JOURNAL OF VIROLOGY

Hepatitis C Virus Nonstructural Protein 5A: Biochemical Characterization of a Novel Structural Class of RNA-Binding Proteins

(2010) J. Hwang et al.   JOURNAL OF VIROLOGY

Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect

(2010) Min Gao et al.   NATURE

The Tumor Suppressor p53: From Structures to Drug Discovery

(2010) A. C. Joerger et al.   Cold Spring Harbor Perspectives in Biology

Domain 3 of non-structural protein 5A from hepatitis C virus is natively unfolded

(2009) Xavier Hanoulle et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of Hepatitis C Virus NS5A Inhibitors

(2009) J. A. Lemm et al.   JOURNAL OF VIROLOGY

A Conserved Proline between Domains II and III of Hepatitis C Virus NS5A Influences both RNA Replication and Virus Assembly

(2009) M. Hughes et al.   JOURNAL OF VIROLOGY

Hepatitis C Virus NS2 Protein Contributes to Virus Particle Assembly via Opposing Epistatic Interactions with the E1-E2 Glycoprotein and NS3-NS4A Enzyme Complexes

(2009) T. Phan et al.   JOURNAL OF VIROLOGY

Crystal Structure of a Novel Dimeric Form of NS5A Domain I Protein from Hepatitis C Virus

(2009) R. A. Love et al.   JOURNAL OF VIROLOGY

Phosphate release contributes to the rate-limiting step for unwinding by an RNA helicase

(2009) Qixin Wang et al.   NUCLEIC ACIDS RESEARCH

Intrinsically Disordered Proteins in Human Diseases: Introducing the D2 Concept

(2008) Vladimir N. Uversky et al.   Annual Review of Biophysics

Functional involvement of Annexin-2 in cAMP induced AQP2 trafficking

(2008) Grazia Tamma et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Regulation of Hepatitis C Virion Production via Phosphorylation of the NS5A Protein

(2008) Timothy L. Tellinghuisen et al.   PLoS Pathogens