Evolution of a Cell Culture-Derived Genotype 1a Hepatitis C Virus (H77S.2) during Persistent Infection with Chronic Hepatitis in a Chimpanzee

The Increasing Burden of Mortality From Viral Hepatitis in the United States Between 1999 and 2007

(2013) Kathleen N. Ly et al.   ANNALS OF INTERNAL MEDICINE

Sofosbuvir and Ribavirin for Hepatitis C Genotype 1 in Patients With Unfavorable Treatment Characteristics

(2013) Anuoluwapo Osinusi et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

In Vivo Emergence of a Novel Mutant L159F/L320F in the NS5B Polymerase Confers Low-Level Resistance to the HCV Polymerase Inhibitors Mericitabine and Sofosbuvir

(2013) Xiao Tong et al.   JOURNAL OF INFECTIOUS DISEASES

Sofosbuvir in combination with peginterferon alfa-2a and ribavirin for non-cirrhotic, treatment-naive patients with genotypes 1, 2, and 3 hepatitis C infection: a randomised, double-blind, phase 2 trial

(2013) Eric Lawitz et al.   LANCET INFECTIOUS DISEASES

Completion of the entire hepatitis C virus life cycle in genetically humanized mice

(2013) Marcus Dorner et al.   NATURE

Global control of hepatitis C: where challenge meets opportunity

(2013) David L Thomas   NATURE MEDICINE

Loss of immune escape mutations during persistent HCV infection in pregnancy enhances replication of vertically transmitted viruses

(2013) Jonathan R Honegger et al.   NATURE MEDICINE

Pathogenesis of chronic viral hepatitis: differential roles of T cells and NK cells

(2013) Barbara Rehermann   NATURE MEDICINE

Hepatitis C in the United States

(2013) Scott D. Holmberg et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nucleotide Polymerase Inhibitor Sofosbuvir plus Ribavirin for Hepatitis C

(2013) Edward J. Gane et al.   NEW ENGLAND JOURNAL OF MEDICINE

IL-1β Production through the NLRP3 Inflammasome by Hepatic Macrophages Links Hepatitis C Virus Infection with Liver Inflammation and Disease

(2013) Amina A. Negash et al.   PLoS Pathogens

Structural Basis of HCV Neutralization by Human Monoclonal Antibodies Resistant to Viral Neutralization Escape

(2013) Thomas Krey et al.   PLoS Pathogens

Highly efficient full-length hepatitis C virus genotype 1 (strain TN) infectious culture system

(2012) Y.-P. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Humanized Mouse Model to Study Hepatitis C Virus Infection, Immune Response, and Liver Disease

(2011) Michael L. Washburn et al.   GASTROENTEROLOGY

Transmission of Clonal Hepatitis C Virus Genomes Reveals the Dominant but Transitory Role of CD8+ T Cells in Early Viral Evolution

(2011) B. Callendret et al.   JOURNAL OF VIROLOGY

Acute hepatitis A virus infection is associated with a limited type I interferon response and persistence of intrahepatic viral RNA

(2011) R. E. Lanford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequential Bottlenecks Drive Viral Evolution in Early Acute Hepatitis C Virus Infection

(2011) Rowena A. Bull et al.   PLoS Pathogens

Protease Inhibitor–Resistant Hepatitis C Virus Mutants With Reduced Fitness From Impaired Production of Infectious Virus

(2010) Tetsuro Shimakami et al.   GASTROENTEROLOGY

Further Insights into the Roles of GTP and the C Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis

(2010) Déborah Harrus et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New horizons for studying human hepatotropic infections

(2010) Ype P. de Jong et al.   JOURNAL OF CLINICAL INVESTIGATION

Hepatitis C Virus Blocks Interferon Effector Function by Inducing Protein Kinase R Phosphorylation

(2009) Urtzi Garaigorta et al.   Cell Host & Microbe

Crystal Structure of a Novel Dimeric Form of NS5A Domain I Protein from Hepatitis C Virus

(2009) R. A. Love et al.   JOURNAL OF VIROLOGY

Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection

(2009) R. E. Lanford et al.   SCIENCE

HCV Induces Oxidative and ER Stress, and Sensitizes Infected Cells to Apoptosis in SCID/Alb-uPA Mice

(2009) Michael A. Joyce et al.   PLoS Pathogens

trans-Complementation of an NS2 Defect in a Late Step in Hepatitis C Virus (HCV) Particle Assembly and Maturation

(2009) MinKyung Yi et al.   PLoS Pathogens

Hepatitis C virus JFH-1 strain infection in chimpanzees is associated with low pathogenicity and emergence of an adaptive mutation

(2008) Takanobu Kato et al.   HEPATOLOGY

In vitro selection of a neutralization-resistant hepatitis C virus escape mutant

(2008) M. Gal-Tanamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interferon signaling and treatment outcome in chronic hepatitis C

(2008) M. Sarasin-Filipowicz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA