Topological Analysis of Hedgehog Acyltransferase, a Multipalmitoylated Transmembrane Protein

Attenuation of Hedgehog Acyltransferase-Catalyzed Sonic Hedgehog Palmitoylation Causes Reduced Signaling, Proliferation and Invasiveness of Human Carcinoma Cells

(2014) Antonios D. Konitsiotis et al.   PLoS One

Architectural Organization of the Metabolic Regulatory Enzyme GhrelinO-Acyltransferase

(2013) Martin S. Taylor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oligomerization of DHHC ProteinS-Acyltransferases

(2013) Jianbin Lai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibitors of Hedgehog acyltransferase block Sonic Hedgehog signaling

(2013) Elissaveta Petrova et al.   Nature Chemical Biology

Single-cell imaging of Wnt palmitoylation by the acyltransferase porcupine

(2013) Xinxin Gao et al.   Nature Chemical Biology

RefSeq: an update on mammalian reference sequences

(2013) Kim D. Pruitt et al.   NUCLEIC ACIDS RESEARCH

Palmitoylated calnexin is a key component of the ribosome-translocon complex

(2012) Asvin KK Lakkaraju et al.   EMBO JOURNAL

DHHC ProteinS-Acyltransferases Use Similar Ping-Pong Kinetic Mechanisms but Display Different Acyl-CoA Specificities

(2012) Benjamin C. Jennings et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Topology of the microsomal glycerol-3-phosphate acyltransferase Gpt2p/Gat1p ofSaccharomyces cerevisiae

(2012) Martin Pagac et al.   MOLECULAR MICROBIOLOGY

The Hedgehog processing pathway is required for NSCLC growth and survival

(2012) J Rodriguez-Blanco et al.   ONCOGENE

A guideline to proteome-wide α-helical membrane protein topology predictions

(2012) Konstantinos D. Tsirigos et al.   PROTEOMICS

Bioorthogonal chemical tagging of protein cholesterylation in living cells

(2011) William P. Heal et al.   CHEMICAL COMMUNICATIONS

Topology of 1-Acyl-sn-glycerol-3-phosphate AcyltransferasesSLC1andALE1and Related Membrane-boundO-Acyltransferases (MBOATs) ofSaccharomyces cerevisiae

(2011) Martin Pagac et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SignalP 4.0: discriminating signal peptides from transmembrane regions

(2011) Thomas Nordahl Petersen et al.   NATURE METHODS

Site-specific analysis of proteinS-acylation by resin-assisted capture

(2010) Michael T. Forrester et al.   JOURNAL OF LIPID RESEARCH

Identification of Conserved Regions and Residues within Hedgehog Acyltransferase Critical for Palmitoylation of Sonic Hedgehog

(2010) John A. Buglino et al.   PLoS One

Learning from Jekyll to control Hyde: Hedgehog signaling in development and cancer

(2010) Monique T. Barakat et al.   TRENDS IN MOLECULAR MEDICINE

Transmembrane protein topology prediction using support vector machines

(2009) Timothy Nugent et al.   BMC BIOINFORMATICS

Mutation of juxtamembrane cysteines in the tetraspanin CD81 affects palmitoylation and alters interaction with other proteins at the cell surface

(2009) Caroline Delandre et al.   EXPERIMENTAL CELL RESEARCH

Acyltransferases for secreted signalling proteins (Review)

(2009) Shu-Chun Chang et al.   MOLECULAR MEMBRANE BIOLOGY

TOPCONS: consensus prediction of membrane protein topology

(2009) A. Bernsel et al.   NUCLEIC ACIDS RESEARCH

Mechanisms of Hedgehog pathway activation in cancer and implications for therapy

(2009) Suzie J. Scales et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Hhat Is a Palmitoylacyltransferase with Specificity forN-Palmitoylation of Sonic Hedgehog

(2008) John A. Buglino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY