Using Markov State Models to Develop a Mechanistic Understanding of Protein Kinase A Regulatory Subunit RIα Activation in Response to cAMP Binding

Signaling through dynamic linkers as revealed by PKA

(2013) M. Akimoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assembly of allosteric macromolecular switches: lessons from PKA

(2012) Susan S. Taylor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Localization and quaternary structure of the PKA RI  holoenzyme

(2012) R. Ilouz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and Allostery of the PKA RII  Tetrameric Holoenzyme

(2012) P. Zhang et al.   SCIENCE

Discussion of Multicyclic Hubbert Modeling as a Method for Forecasting Future Petroleum Production

(2011) Ken B. Anderson et al.   ENERGY & FUELS

Realizing the Allosteric Potential of the Tetrameric Protein Kinase A RIα Holoenzyme

(2011) Angela J. Boettcher et al.   STRUCTURE

Allosteric Communication between cAMP Binding Sites in the RI Subunit of Protein Kinase A Revealed by NMR

(2010) In-Ja L. Byeon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphodiesterases Catalyze Hydrolysis of cAMP-bound to Regulatory Subunit of Protein Kinase A and Mediate Signal Termination

(2010) Balakrishnan Shenbaga Moorthy et al.   MOLECULAR & CELLULAR PROTEOMICS

Cyclic AMP Analog Blocks Kinase Activation by Stabilizing Inactive Conformation: Conformational Selection Highlights a New Concept in Allosteric Inhibitor Design

(2010) Suguna Badireddy et al.   MOLECULAR & CELLULAR PROTEOMICS

Sensing Domain Dynamics in Protein Kinase A-Iα Complexes by Solution X-ray Scattering

(2009) Cecilia Y. Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel activating effect of the regulatory subunit of protein kinase A on catalytic subunit activity

(2008) Jimena Rinaldi et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

A computational framework for derivative-free optimization of cardiovascular geometries

(2008) Alison L. Marsden et al.   COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING

Virtual Cell modelling and simulation software environment

(2008) I.I. Moraru et al.   IET Systems Biology