Assembly of allosteric macromolecular switches: lessons from PKA

Structural Basis for the Regulation of Protein Kinase A by Activation Loop Phosphorylation

(2012) Jon M. Steichen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of N-Terminal Myristylation in the Structure and Regulation of cAMP-Dependent Protein Kinase

(2012) Adam C. Bastidas et al.   JOURNAL OF MOLECULAR BIOLOGY

Exploring the Plasmodium falciparum cyclic-adenosine monophosphate (cAMP)-dependent protein kinase (PfPKA) as a therapeutic target

(2012) Nina M. Haste et al.   MICROBES AND INFECTION

Localization and quaternary structure of the PKA RI  holoenzyme

(2012) R. Ilouz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and Allostery of the PKA RII  Tetrameric Holoenzyme

(2012) P. Zhang et al.   SCIENCE

Mechanism of Intracellular cAMP Sensor Epac2 Activation

(2011) Sheng Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Rate of NF-κB Nuclear Translocation Is Regulated by PKA and A Kinase Interacting Protein 1

(2011) Charles C. King et al.   PLoS One

Realizing the Allosteric Potential of the Tetrameric Protein Kinase A RIα Holoenzyme

(2011) Angela J. Boettcher et al.   STRUCTURE

PKA regulatory subunits mediate synergy among conserved G-protein-coupled receptor cascades

(2011) Eduard Stefan et al.   Nature Communications

Specificity and spatial dynamics of protein kinase A signaling organized by A-kinase-anchoring proteins

(2010) Guillaume Pidoux et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Signaling diversity of PKA achieved via a Ca2+-cAMP-PKA oscillatory circuit

(2010) Qiang Ni et al.   Nature Chemical Biology

Importance of the A-helix of the catalytic subunit of cAMP-dependent protein kinase for stability and for orienting subdomains at the cleft interface

(2010) Friedrich W. Herberg et al.   PROTEIN SCIENCE

Structure of D-AKAP2:PKA RI Complex: Insights into AKAP Specificity and Selectivity

(2010) Ganapathy N. Sarma et al.   STRUCTURE

Protein kinases: evolution of dynamic regulatory proteins

(2010) Susan S. Taylor et al.   TRENDS IN BIOCHEMICAL SCIENCES

Global Consequences of Activation Loop Phosphorylation on Protein Kinase A

(2009) Jon M. Steichen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel Isoform-Specific Interfaces Revealed by PKA RIIβ Holoenzyme Structures

(2009) Simon H.J. Brown et al.   JOURNAL OF MOLECULAR BIOLOGY

A chimeric mechanism for polyvalenttrans-phosphorylation of PKA by PDK1

(2009) Robert A. Romano et al.   PROTEIN SCIENCE

Disruption of the RII subunit of PKA reverses the obesity syndrome of agouti lethal yellow mice

(2008) T. A. Czyzyk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A helix scaffold for the assembly of active protein kinases

(2008) A. P. Kornev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Generalized Allosteric Mechanism for cis-Regulated Cyclic Nucleotide Binding Domains

(2008) Alexandr P. Kornev et al.   PLoS Computational Biology