Inhibition of Plasma Kallikrein by a Highly Specific Active Site Blocking Antibody

The prophylaxis of hereditary angioedema attacks with recombinant human C1 inhibitor: who will take advantage of the individualized treatment approach?

(2015) G. Porebski et al.   ALLERGY

A phase 1 study investigating DX-2930 in healthy subjects

(2014) Yung Chyung et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Antithrombotic Effect of Antisense Factor XI Oligonucleotide Treatment in Primates

(2013) Jeffrey R. Crosby et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inhibiting the intrinsic pathway of coagulation with a factor XII-targeting RNA aptamer

(2013) R. S. Woodruff et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Kininogen deficiency protects from ischemic neurodegeneration in mice by reducing thrombosis, blood-brain barrier damage, and inflammation

(2012) F. Langhauser et al.   BLOOD

Current Management Options for Hereditary Angioedema

(2012) Konrad Bork   CURRENT ALLERGY AND ASTHMA REPORTS

Thrombotic Events Associated with C1 Esterase Inhibitor Products in Patients with Hereditary Angioedema: Investigation from the United States Food and Drug Administration Adverse Event Reporting System Database

(2012) Pranav K. Gandhi et al.   PHARMACOTHERAPY

Plasma kallikrein: Novel functions for an old protease

(2012) Thomas Renné et al.   THROMBOSIS AND HAEMOSTASIS

Effects of plasma kallikrein deficiency on haemostasis and thrombosis in mice: Murine Ortholog of the Fletcher Trait

(2012) J. E. Bird et al.   THROMBOSIS AND HAEMOSTASIS

Selective depletion of plasma prekallikrein or coagulation factor XII inhibits thrombosis in mice without increased risk of bleeding

(2011) A. S. Revenko et al.   BLOOD

Plasma Kallikrein Mediates Retinal Vascular Dysfunction and Induces Retinal Thickening in Diabetic Rats

(2011) A. Clermont et al.   DIABETES

Prospective, double-blind, placebo-controlled trials of ecallantide for acute attacks of hereditary angioedema

(2011) Leslie E Stolz et al.   Expert Review of Clinical Immunology

Mast Cells Increase Vascular Permeability by Heparin-Initiated Bradykinin Formation In Vivo

(2011) Chris Oschatz et al.   IMMUNITY

A Reverse Binding Motif That Contributes to Specific Protease Inhibition by Antibodies

(2011) Eric L. Schneider et al.   JOURNAL OF MOLECULAR BIOLOGY

The many faces of the contact pathway and their role in thrombosis

(2011) Rebecca S. Woodruff et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Hereditary angioedema: a current state-of-the-art review, V: attenuated androgens for the treatment of hereditary angioedema

(2010) Aleena Banerji et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Benefits and risks of danazol in hereditary angioedema: a long-term survey of 118 patients

(2010) Konrad Bork et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs)

(2010) Peter Goettig et al.   BIOCHIMIE

Laminin promotes coagulation and thrombus formation in a factor XII-dependent manner

(2010) T. C. WHITE-ADAMS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Nanofiltered C1 Inhibitor Concentrate for Treatment of Hereditary Angioedema

(2010) Bruce L. Zuraw et al.   NEW ENGLAND JOURNAL OF MEDICINE

Congenital prekallikrein deficiency

(2010) Antonio Girolami et al.   Expert Review of Hematology

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Specific inhibition of tissue kallikrein 1 with a human monoclonal antibody reveals a potential role in airway diseases

(2009) Daniel J. Sexton et al.   BIOCHEMICAL JOURNAL

Dual role of collagen in factor XII-dependent thrombus formation

(2009) P. E. J. van der Meijden et al.   BLOOD

Platelet Polyphosphates Are Proinflammatory and Procoagulant Mediators In Vivo

(2009) Felicitas Müller et al.   CELL

Ecallantide: its pharmacology, pharmacokinetics, clinical efficacy and tolerability

(2009) Jonathan A Bernstein et al.   Expert Review of Clinical Immunology

High molecular weight kininogen binds to laminin - characterization and kinetic analysis

(2009) Inger Schousboe et al.   FEBS Journal

The kallikrein–kinin system in diabetic retinopathy: Lessons for the kidney

(2008) J.A. Phipps et al.   KIDNEY INTERNATIONAL

Surface-adsorbed fibrinogen and fibrin may activate the contact activation system

(2008) J. Sanchez et al.   THROMBOSIS RESEARCH