The E3 Deubiquitinase USP17 Is a Positive Regulator of Retinoic Acid-related Orphan Nuclear Receptor γt (RORγt) in Th17 Cells

The Ubiquitin Ligase Stub1 Negatively Modulates Regulatory T Cell Suppressive Activity by Promoting Degradation of the Transcription Factor Foxp3

(2013) Zuojia Chen et al.   IMMUNITY

Stabilization of the Transcription Factor Foxp3 by the Deubiquitinase USP7 Increases Treg-Cell-Suppressive Capacity

(2013) Jorg van Loosdregt et al.   IMMUNITY

Identification of the E3 Deubiquitinase Ubiquitin-specific Peptidase 21 (USP21) as a Positive Regulator of the Transcription Factor GATA3

(2013) Jing Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

USP18 inhibits NF-κB and NFAT activation during Th17 differentiation by deubiquitinating the TAK1–TAB1 complex

(2013) Xikui Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Leptin-Induced ROR t Expression in CD4+ T Cells Promotes Th17 Responses in Systemic Lupus Erythematosus

(2013) Y. Yu et al.   JOURNAL OF IMMUNOLOGY

AT-Rich-Interactive Domain-Containing Protein 5A Functions as a Negative Regulator of Retinoic Acid Receptor-Related Orphan Nuclear Receptor γt-Induced Th17 Cell Differentiation

(2013) Yukari Saito et al.   Arthritis & Rheumatology

Innate Lymphoid Cells: Emerging Insights in Development, Lineage Relationships, and Function

(2012) Hergen Spits et al.   Annual Review of Immunology

Upstream Stimulating Factors Regulate the Expression of ROR T in Human Lymphocytes

(2012) M. Ratajewski et al.   JOURNAL OF IMMUNOLOGY

The potential role of Th17 cells and Th17-related cytokines in the pathogenesis of lupus nephritis

(2012) D-Y Chen et al.   LUPUS

Negative regulation of IL-17-mediated signaling and inflammation by the ubiquitin-specific protease USP25

(2012) Bo Zhong et al.   NATURE IMMUNOLOGY

Induction and molecular signature of pathogenic TH17 cells

(2012) Youjin Lee et al.   NATURE IMMUNOLOGY

Effector T-cell subsets in systemic lupus erythematosus

(2011) Min S. Shin et al.   CURRENT OPINION IN RHEUMATOLOGY

PDLIM2 Inhibits T Helper 17 Cell Development and Granulomatous Inflammation Through Degradation of STAT3

(2011) T. Tanaka et al.   Science Signaling

The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility

(2011) Michelle de la Vega et al.   Nature Communications

USP10 Regulates p53 Localization and Stability by Deubiquitinating p53

(2010) Jian Yuan et al.   CELL

The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling

(2010) Rui Chen et al.   CELL RESEARCH

Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes

(2009) Francisca E. Reyes-Turcu et al.   Annual Review of Biochemistry

Plasticity of CD4+ T Cell Lineage Differentiation

(2009) Liang Zhou et al.   IMMUNITY

USP17 Regulates Ras Activation and Cell Proliferation by Blocking RCE1 Activity

(2009) James F. Burrows et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Th17 cells in rheumatoid arthritis and systemic lupus erythematosus

(2009) A. B. Pernis   JOURNAL OF INTERNAL MEDICINE

Foxp3 Inhibits RORγt-mediatedIL-17AmRNA Transcription through Direct Interaction with RORγt

(2008) Kenji Ichiyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induction and effector functions of TH17 cells

(2008) Estelle Bettelli et al.   NATURE

A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses

(2008) Elisabetta Volpe et al.   NATURE IMMUNOLOGY

The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt

(2008) Nicolas Manel et al.   NATURE IMMUNOLOGY