AT-Rich-Interactive Domain-Containing Protein 5A Functions as a Negative Regulator of Retinoic Acid Receptor-Related Orphan Nuclear Receptor γt-Induced Th17 Cell Differentiation

Efficacy and safety of secukinumab in patients with rheumatoid arthritis: a phase II, dose-finding, double-blind, randomised, placebo controlled study

(2012) Mark C Genovese et al.   ANNALS OF THE RHEUMATIC DISEASES

A Validated Regulatory Network for Th17 Cell Specification

(2012) Maria Ciofani et al.   CELL

Emerging role of interleukin-22 in autoimmune diseases

(2012) Hai-Feng Pan et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Targeting the Th17 pathway in psoriasis

(2012) M. Merle Elloso et al.   JOURNAL OF LEUKOCYTE BIOLOGY

RORγt-dependent IL-17A-producing cells in the pathogenesis of intestinal inflammation

(2012) T Kanai et al.   Mucosal Immunology

Understanding the dynamics: pathways involved in the pathogenesis of rheumatoid arthritis

(2012) E. Choy   RHEUMATOLOGY

TH17 cytokines in autoimmune neuro-inflammation

(2011) Burkhard Becher et al.   CURRENT OPINION IN IMMUNOLOGY

Arid5a cooperates with Sox9 to stimulate chondrocyte-specific transcription

(2011) Katsuhiko Amano et al.   MOLECULAR BIOLOGY OF THE CELL

Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity

(2011) Jun R. Huh et al.   NATURE

Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand

(2011) Laura A. Solt et al.   NATURE

Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in TH17 cells

(2011) Sascha Rutz et al.   NATURE IMMUNOLOGY

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production

(2010) J. P. van Hamburg et al.   ARTHRITIS AND RHEUMATISM

Roles of Bcl-3 in the Pathogenesis of Murine Type 1 Diabetes

(2010) Q. Ruan et al.   DIABETES

Ranking differentially expressed genes from Affymetrix gene expression data: methods with reproducibility, sensitivity, and specificity

(2009) Koji Kadota et al.   Algorithms for Molecular Biology

Protein geranylgeranylation regulates the balance between Th17 cells and Foxp3+ regulatory T cells

(2009) S.-i. Kagami et al.   INTERNATIONAL IMMUNOLOGY

Type 17 T helper cells—origins, features and possible roles in rheumatic disease

(2009) Francesco Annunziato et al.   Nature Reviews Rheumatology

Cytokines as Therapeutic Targets: Advances and Limitations

(2008) Clemens Scheinecker et al.   IMMUNITY

Molecular Antagonism and Plasticity of Regulatory and Inflammatory T Cell Programs

(2008) Xuexian O. Yang et al.   IMMUNITY

Foxp3 Inhibits RORγt-mediatedIL-17AmRNA Transcription through Direct Interaction with RORγt

(2008) Kenji Ichiyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Development and characterization of IL-21–producing CD4+T cells

(2008) Akira Suto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TH-17 cells in rheumatoid arthritis

(2008) Shiva Shahrara et al.   ARTHRITIS RESEARCH & THERAPY