Substituted Cysteine Accessibility Reveals a Novel Transmembrane 2–3 Reentrant Loop and Functional Role for Transmembrane Domain 2 in the Human Proton-coupled Folate Transporter

Role of the fourth transmembrane domain in proton-coupled folate transporter function as assessed by the substituted cysteine accessibility method

(2013) Daniel Sanghoon Shin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Identification of a functionally critical GXXG motif and its relationship to the folate binding site of the proton-coupled folate transporter (PCFT-SLC46A1)

(2012) Rongbao Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The human proton-coupled folate transporter

(2012) Sita Kugel Desmoulin et al.   CANCER BIOLOGY & THERAPY

Identification and Functional Impact of Homo-oligomers of the Human Proton-coupled Folate Transporter

(2011) Zhanjun Hou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prevalence of a Loss-of-Function Mutation in the Proton-Coupled Folate Transporter Gene (PCFT-SLC46A1) Causing Hereditary Folate Malabsorption in Puerto Rico

(2011) Kris M. Mahadeo et al.   JOURNAL OF PEDIATRICS

Identification of novel mutations in the proton-coupled folate transporter (PCFT-SLC46A1) associated with hereditary folate malabsorption

(2011) Daniel Sanghoon Shin et al.   MOLECULAR GENETICS AND METABOLISM

Properties of the Arg376 residue of the proton-coupled folate transporter (PCFT-SLC46A1) and a glutamine mutant causing hereditary folate malabsorption

(2010) Kris Mahadeo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Membrane Topological Analysis of the Proton-Coupled Folate Transporter (PCFT-SLC46A1) by the Substituted Cysteine Accessibility Method

(2010) Rongbao Zhao et al.   BIOCHEMISTRY

Functional roles of aspartate residues of the proton-coupled folate transporter (PCFT-SLC46A1); a D156Y mutation causing hereditary folate malabsorption

(2010) D. S. Shin et al.   BLOOD

Targeting the Proton-Coupled Folate Transporter for Selective Delivery of 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolate Inhibitors of De Novo Purine Biosynthesis in the Chemotherapy of Solid Tumors

(2010) S. K. Desmoulin et al.   MOLECULAR PHARMACOLOGY

MUTATION OF THE PROTON-COUPLED FOLATE TRANSPORTER GENE (PCFT-SLC46A1) IN TURKISH SIBLINGS WITH HEREDITARY FOLATE MALABSORPTION

(2010) Berna Atabay et al.   PEDIATRIC HEMATOLOGY AND ONCOLOGY

An Analysis of Reentrant Loops

(2010) Changhui Yan et al.   PROTEIN JOURNAL

Role of the glutamate 185 residue in proton translocation mediated by the proton-coupled folate transporter SLC46A1

(2009) Ersin Selcuk Unal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Hereditary folate malabsorption: A positively charged amino acid at position 113 of the proton-coupled folate transporter (PCFT/SLC46A1) is required for folic acid binding

(2009) Inbal Lasry et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Reversible severe combined immunodeficiency phenotype secondary to a mutation of the proton-coupled folate transporter

(2009) Arturo Borzutzky et al.   CLINICAL IMMUNOLOGY

The Functional Roles of the His247and His281Residues in Folate and Proton Translocation Mediated by the Human Proton-coupled Folate Transporter SLC46A1

(2009) Ersin Selcuk Unal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypermethylation of the human proton-coupled folate transporter (SLC46A1) minimal trancriptional regulatory region in an antifolate-resistant HeLa cell line

(2009) N. K. Diop-Bove et al.   MOLECULAR CANCER THERAPEUTICS

A novel PCFT gene mutation (p.Cys66LeufsX99) causing hereditary folate malabsorption

(2009) Esther Meyer et al.   MOLECULAR GENETICS AND METABOLISM

Functional characterization of PCFT/HCP1 as the molecular entity of the carrier-mediated intestinal folate transport system in the rat model

(2008) Katsuhisa Inoue et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

N-linked glycosylation and its impact on the electrophoretic mobility and function of the human proton-coupled folate transporter (HsPCFT)

(2008) Ersin Selcuk Unal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

A novel loss-of-function mutation in the proton-coupled folate transporter from a patient with hereditary folate malabsorption reveals that Arg 113 is crucial for function

(2008) I. Lasry et al.   BLOOD

The Clinical Course and Genetic Defect in the PCFT Gene in a 27-Year-Old Woman with Hereditary Folate Malabsorption

(2008) Sang Hee Min et al.   JOURNAL OF PEDIATRICS

Apical membrane targeting and trafficking of the human proton-coupled transporter in polarized epithelia

(2007) Veedamali S. Subramanian et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY