No Amelioration of Uromodulin Maturation and Trafficking Defect by Sodium 4-Phenylbutyratein Vivo

Type of uromodulin mutation and allelic status influence onset and severity of uromodulin-associated kidney disease in mice

(2013) Elisabeth Kemter et al.   HUMAN MOLECULAR GENETICS

Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression

(2013) Matteo Trudu et al.   NATURE MEDICINE

Clinical and Experimental Applications of Sodium Phenylbutyrate

(2013) Tommaso Iannitti et al.   Drugs in research & development

2012 American College of Rheumatology guidelines for management of gout. Part 1: Systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia

(2012) Dinesh Khanna et al.   ARTHRITIS CARE & RESEARCH

Endoplasmic Reticulum Stress in UMOD-Related Kidney Disease: A Human Pathologic Study

(2011) Julien Adam et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Phenotype and Outcome in Hereditary Tubulointerstitial Nephritis Secondary to UMOD Mutations

(2011) G. Bollee et al.   Clinical Journal of the American Society of Nephrology

4-Phenylbutyrate Stimulates Hsp70 Expression through the Elp2 Component of Elongator and STAT-3 in Cystic Fibrosis Epithelial Cells

(2011) Laurence Suaud et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular and Cellular Effects of Tamm-Horsfall Protein Mutations and Their Rescue by Chemical Chaperones

(2011) Lijie Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The rediscovery of uromodulin (Tamm–Horsfall protein): from tubulointerstitial nephropathy to chronic kidney disease

(2011) Luca Rampoldi et al.   KIDNEY INTERNATIONAL

Hierarchies of NF-κB target-gene regulation

(2011) Stephen T Smale   NATURE IMMUNOLOGY

Non-canonical NF-κB signaling pathway

(2010) Shao-Cong Sun   CELL RESEARCH

Uromodulin is expressed in renal primary cilia and UMOD mutations result in decreased ciliary uromodulin expression

(2010) Frank Zaucke et al.   HUMAN MOLECULAR GENETICS

Uromodulin-Associated Kidney Disease

(2010) Anthony J. Bleyer et al.   NEPHRON CLINICAL PRACTICE

Uromodulin mutations causing familial juvenile hyperuricaemic nephropathy lead to protein maturation defects and retention in the endoplasmic reticulum

(2009) Siân E. Williams et al.   HUMAN MOLECULAR GENETICS

The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response

(2009) Sana Basseri et al.   JOURNAL OF LIPID RESEARCH

Phenylbutyrate Ameliorates Cognitive Deficit and Reduces Tau Pathology in an Alzheimer's Disease Mouse Model

(2009) Ana Ricobaraza et al.   NEUROPSYCHOPHARMACOLOGY

Uromodulin storage disease

(2007) S.H. Nasr et al.   KIDNEY INTERNATIONAL