Molecular and Cellular Effects of Tamm-Horsfall Protein Mutations and Their Rescue by Chemical Chaperones

The rediscovery of uromodulin (Tamm–Horsfall protein): from tubulointerstitial nephropathy to chronic kidney disease

(2011) Luca Rampoldi et al.   KIDNEY INTERNATIONAL

Uromodulin is expressed in renal primary cilia and UMOD mutations result in decreased ciliary uromodulin expression

(2010) Frank Zaucke et al.   HUMAN MOLECULAR GENETICS

Uromodulin and Translational Medicine: Will the SNPs Bring Zip to Clinical Practice?

(2010) J. R. Sedor   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Protein quality control in the ER: The recognition of misfolded proteins

(2010) Pekka Määttänen et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Hereditary Interstitial Kidney Disease

(2010) Anthony J. Bleyer et al.   SEMINARS IN NEPHROLOGY

Association of Variants at UMOD with Chronic Kidney Disease and Kidney Stones—Role of Age and Comorbid Diseases

(2010) Daniel F. Gudbjartsson et al.   PLoS Genetics

Optimizing Therapy With Allopurinol: Factors Limiting Hypouricemic Efficacy

(2009) Yewon Chung et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Uromodulin mutations causing familial juvenile hyperuricaemic nephropathy lead to protein maturation defects and retention in the endoplasmic reticulum

(2009) Siân E. Williams et al.   HUMAN MOLECULAR GENETICS

Uromodulin Levels Associate with a Common UMOD Variant and Risk for Incident CKD

(2009) A. Kottgen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Tamm-Horsfall Protein Protects Against Urinary Tract Infection by Proteus Mirabilis

(2009) Hajamohideen S. Raffi et al.   JOURNAL OF UROLOGY

Multiple loci associated with indices of renal function and chronic kidney disease

(2009) Anna Köttgen et al.   NATURE GENETICS

Analysis of Uromodulin Polymerization Provides New Insights into the Mechanisms Regulating ZP Domain-mediated Protein Assembly

(2008) Céline Schaeffer et al.   MOLECULAR BIOLOGY OF THE CELL

Uromodulin storage disease

(2007) S.H. Nasr et al.   KIDNEY INTERNATIONAL