Type of uromodulin mutation and allelic status influence onset and severity of uromodulin-associated kidney disease in mice

Common genetic variants of the human uromodulin gene regulate transcription and predict plasma uric acid levels

(2013) Jia Han et al.   KIDNEY INTERNATIONAL

Novel biomarkers of acute kidney injury and failure: clinical applicability

(2012) J. Mårtensson et al.   BRITISH JOURNAL OF ANAESTHESIA

Tamm-Horsfall Protein Regulates Circulating and Renal Cytokines by Affecting Glomerular Filtration Rate and Acting as a Urinary Cytokine Trap

(2012) Yan Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epithelial-mesenchymal crosstalk alteration in kidney fibrosis

(2012) Marco Prunotto et al.   JOURNAL OF PATHOLOGY

The Delicate Balance Between Secreted Protein Folding and Endoplasmic Reticulum-Associated Degradation in Human Physiology

(2012) Christopher J. Guerriero et al.   PHYSIOLOGICAL REVIEWS

Characterization of a Recurrent In-frame UMOD Indel Mutation Causing Late-onset Autosomal Dominant End-Stage Renal Failure

(2011) G. D. Smith et al.   Clinical Journal of the American Society of Nephrology

Phenotype and Outcome in Hereditary Tubulointerstitial Nephritis Secondary to UMOD Mutations

(2011) G. Bollee et al.   Clinical Journal of the American Society of Nephrology

The rediscovery of uromodulin (Tamm–Horsfall protein): from tubulointerstitial nephropathy to chronic kidney disease

(2011) Luca Rampoldi et al.   KIDNEY INTERNATIONAL

A transgenic mouse model for uromodulin-associated kidney diseases shows specific tubulo-interstitial damage, urinary concentrating defect and renal failure

(2010) Ilenia Bernascone et al.   HUMAN MOLECULAR GENETICS

Uromodulin is expressed in renal primary cilia and UMOD mutations result in decreased ciliary uromodulin expression

(2010) Frank Zaucke et al.   HUMAN MOLECULAR GENETICS

New loci associated with kidney function and chronic kidney disease

(2010) Anna Köttgen et al.   NATURE GENETICS

Uromodulin-Associated Kidney Disease

(2010) Anthony J. Bleyer et al.   NEPHRON CLINICAL PRACTICE

Childhood course of renal insufficiency in a family with a uromodulin gene mutation

(2010) Péter Schäffer et al.   PEDIATRIC NEPHROLOGY

Association of Variants at UMOD with Chronic Kidney Disease and Kidney Stones—Role of Age and Comorbid Diseases

(2010) Daniel F. Gudbjartsson et al.   PLoS Genetics

Uromodulin mutations causing familial juvenile hyperuricaemic nephropathy lead to protein maturation defects and retention in the endoplasmic reticulum

(2009) Siân E. Williams et al.   HUMAN MOLECULAR GENETICS

Multiple loci associated with indices of renal function and chronic kidney disease

(2009) Anna Köttgen et al.   NATURE GENETICS

Endoplasmic Reticulum Stress in the Kidney as a Novel Mediator of Kidney Injury

(2009) Reiko Inagi   NEPHRON EXPERIMENTAL NEPHROLOGY

Immature Renal Structures Associated With a Novel UMOD Sequence Variant

(2008) Elisa Benetti et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Dysfunction of the ER chaperone BiP accelerates the renal tubular injury

(2008) Keita Kimura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

One step at a time: endoplasmic reticulum-associated degradation

(2008) Shruthi S. Vembar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Production and Characterization of Transgenic Mice Harboring Mutant HumanUMODGene

(2008) Yuichi Takiue et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

Uromodulin storage disease

(2007) S.H. Nasr et al.   KIDNEY INTERNATIONAL