High Glucose Forces a Positive Feedback Loop Connecting Akt Kinase and FoxO1 Transcription Factor to Activate mTORC1 Kinase for Mesangial Cell Hypertrophy and Matrix Protein Expression

Catalase expression in MCF-7 breast cancer cells is mainly controlled by PI3K/Akt/mTor signaling pathway

(2014) Christophe Glorieux et al.   BIOCHEMICAL PHARMACOLOGY

Nox as a target for diabetic complications

(2013) Yves Gorin et al.   CLINICAL SCIENCE

Mammalian Target of Rapamycin Regulates Nox4-Mediated Podocyte Depletion in Diabetic Renal Injury

(2013) Assaad A. Eid et al.   DIABETES

Transforming Growth Factor β Integrates Smad 3 to Mechanistic Target of Rapamycin Complexes to Arrest Deptor Abundance for Glomerular Mesangial Cell Hypertrophy

(2013) Falguni Das et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Forkhead box class O transcription factors in liver function and disease

(2013) Irina Tikhanovich et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Acatalasemia and diabetes mellitus

(2012) László Góth et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Physiological Roles of Mitochondrial Reactive Oxygen Species

(2012) Laura A. Sena et al.   MOLECULAR CELL

A Glimpse of Various Pathogenetic Mechanisms of Diabetic Nephropathy

(2011) Yashpal S. Kanwar et al.   Annual Review of Pathology-Mechanisms of Disease

Hepatic Suppression ofFoxo1andFoxo3Causes Hypoglycemia and Hyperlipidemia in Mice

(2011) Kebin Zhang et al.   ENDOCRINOLOGY

MicroRNA-21 Orchestrates High Glucose-induced Signals to TOR Complex 1, Resulting in Renal Cell Pathology in Diabetes

(2011) Nirmalya Dey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reactive oxygen species derived from Nox4 mediateBMP2gene transcription and osteoblast differentiation

(2010) Chandi C. Mandal et al.   BIOCHEMICAL JOURNAL

Literature-based discovery of diabetes- and ROS-related targets

(2010) Junguk Hur et al.   BMC Medical Genomics

FoxOs Inhibit mTORC1 and Activate Akt by Inducing the Expression of Sestrin3 and Rictor

(2010) Chia-Chen Chen et al.   DEVELOPMENTAL CELL

PRAS40 acts as a nodal regulator of high glucose-induced TORC1 activation in glomerular mesangial cell hypertrophy

(2010) Nirmalya Dey et al.   JOURNAL OF CELLULAR PHYSIOLOGY

PAI-1 and kidney fibrosis

(2009) Li-Jun Ma   Frontiers in Bioscience-Landmark

Akt1 Intramitochondrial Cycling Is a Crucial Step in the Redox Modulation of Cell Cycle Progression

(2009) Valeria Gabriela Antico Arciuch et al.   PLoS One

Diabetic Nephropathy: Mechanisms of Renal Disease Progression

(2008) Yashpal S. Kanwar et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Glycogen Synthase Kinase 3β Is a Novel Regulator of High Glucose- and High Insulin-induced Extracellular Matrix Protein Synthesis in Renal Proximal Tubular Epithelial Cells

(2008) Meenalakshmi M. Mariappan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Raptor-rictor axis in TGFβ-induced protein synthesis

(2007) Falguni Das et al.   CELLULAR SIGNALLING