Forkhead box class O transcription factors in liver function and disease

Lysine methylation of FOXO3 regulates oxidative stress-induced neuronal cell death

(2012) Qi Xie et al.   EMBO REPORTS

FOXO3 as a new IKK-ε-controlled check-point of regulation of IFN-β expression

(2012) Lionel Luron et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Modulation of glutamine metabolism by the PI(3)K–PKB–FOXO network regulates autophagy

(2012) Kristan E. van der Vos et al.   NATURE CELL BIOLOGY

Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1

(2012) Mingjian Lu et al.   NATURE MEDICINE

Regulation of FoxO transcription factors by acetylation and protein–protein interactions

(2011) Hiroaki Daitoku et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis

(2011) Maria M. Mihaylova et al.   CELL

Targeting FoxO1 for Hypertriglyceridemia

(2011) Dae Hyun Kim et al.   CURRENT DRUG TARGETS

Hepatic Suppression ofFoxo1andFoxo3Causes Hypoglycemia and Hyperlipidemia in Mice

(2011) Kebin Zhang et al.   ENDOCRINOLOGY

Malnutrition Impairs Interferon Signaling Through mTOR and FoxO Pathways in Patients With Chronic Hepatitis C

(2011) Masao Honda et al.   GASTROENTEROLOGY

Phosphorylation of FOXO3a on Ser-7 by p38 Promotes Its Nuclear Localization in Response to Doxorubicin

(2011) Ka-Kei Ho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatic FoxOs Regulate Lipid Metabolism via Modulation of Expression of the Nicotinamide Phosphoribosyltransferase Gene

(2011) Rongya Tao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatitis C Virus Infection Promotes Hepatic Gluconeogenesis through an NS5A-Mediated, FoxO1-Dependent Pathway

(2011) L. Deng et al.   JOURNAL OF VIROLOGY

Regulation of glucose homeostasis through a XBP-1–FoxO1 interaction

(2011) Yingjiang Zhou et al.   NATURE MEDICINE

Uncoupling of Acetylation from Phosphorylation Regulates FoxO1 Function Independent of Its Subcellular Localization

(2010) Li Qiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatitis C Virus Differentially Modulates Activation of Forkhead Transcription Factors and Insulin-Induced Metabolic Gene Expression

(2010) A. Banerjee et al.   JOURNAL OF VIROLOGY

Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

(2010) Ying Zhao et al.   NATURE CELL BIOLOGY

FoxO, Autophagy, and Cardiac Remodeling

(2010) Anwarul Ferdous et al.   Journal of Cardiovascular Translational Research

p38α blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1α- to FoxO-dependent transcription

(2009) F Chiacchiera et al.   CELL DEATH AND DIFFERENTIATION

Activation of the AMPK-FOXO3 Pathway Reduces Fatty Acid-Induced Increase in Intracellular Reactive Oxygen Species by Upregulating Thioredoxin

(2009) X.-N. Li et al.   DIABETES

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

The Expression and Prognosis of FOXO3a and Skp2 in Human Hepatocellular Carcinoma

(2009) Mudan Lu et al.   PATHOLOGY & ONCOLOGY RESEARCH

Association ofFOXO3Avariation with human longevity confirmed in German centenarians

(2009) Friederike Flachsbart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FoxO transcription factors in oxidative stress response and ageing – a new fork on the way to longevity?

(2008) Daniel G. Sedding   BIOLOGICAL CHEMISTRY

Increased Expression and Activity of the Transcription Factor FOXO1 in Nonalcoholic Steatohepatitis

(2008) L. Valenti et al.   DIABETES

O-glycosylation of FoxO1 increases its transcriptional activity towards the glucose 6-phosphatase gene

(2008) MeiShiue Kuo et al.   FEBS LETTERS

A PGC-1α-O-GlcNAc Transferase Complex Regulates FoxO Transcription Factor Activity in Response to Glucose

(2008) Michael P. Housley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

O-GlcNAc Regulates FoxO Activation in Response to Glucose

(2008) Michael P. Housley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT2 Suppresses Adipocyte Differentiation by Deacetylating FOXO1 and Enhancing FOXO1's Repressive Interaction with PPARγ

(2008) Fei Wang et al.   MOLECULAR BIOLOGY OF THE CELL

Arginine Methylation of FOXO Transcription Factors Inhibits Their Phosphorylation by Akt

(2008) Kazuyuki Yamagata et al.   MOLECULAR CELL

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

(2008) Jer-Yen Yang et al.   NATURE CELL BIOLOGY

A brief introduction to FOXOlogy

(2008) B M Th Burgering   ONCOGENE

FOXO-binding partners: it takes two to tango

(2008) K E van der Vos et al.   ONCOGENE

FOXO animal models reveal a variety of diverse roles for FOXO transcription factors

(2008) K C Arden   ONCOGENE

The FoxO code

(2008) D R Calnan et al.   ONCOGENE

FOXO3A genotype is strongly associated with human longevity

(2008) B. J. Willcox et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of FOXO1 by Cdk1 in Cycling Cells and Postmitotic Neurons

(2008) Z. Yuan et al.   SCIENCE