Monoacylglycerol Acyltransferase-2 Is a Tetrameric Enzyme That Selectively Heterodimerizes with Diacylglycerol Acyltransferase-1
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Monoacylglycerol Acyltransferase-2 Is a Tetrameric Enzyme That Selectively Heterodimerizes with Diacylglycerol Acyltransferase-1
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 289, Issue 15, Pages 10909-10918
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2014-02-27
DOI
10.1074/jbc.m113.530022
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Defining the key pharmacophore elements of PF-04620110: Discovery of a potent, orally-active, neutral DGAT-1 inhibitor
- (2013) Robert L. Dow et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Identification and design of a novel series of MGAT2 inhibitors
- (2013) Jonas G. Barlind et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Diacylglycerol acyltransferase-1 inhibition enhances intestinal fatty acid oxidation and reduces energy intake in rats
- (2013) Gudrun Schober et al. JOURNAL OF LIPID RESEARCH
- Identification and Preliminary Characterization of a Potent, Safe, and Orally Efficacious Inhibitor of Acyl-CoA:Diacylglycerol Acyltransferase 1
- (2012) Vince S. C. Yeh et al. JOURNAL OF MEDICINAL CHEMISTRY
- MGAT2 deficiency ameliorates high-fat diet-induced obesity and insulin resistance by inhibiting intestinal fat absorption in mice
- (2012) Takuma Tsuchida et al. Lipids in Health and Disease
- Glycerolipid Acyltransferases in Triglyceride Metabolism and Energy Homeostasis-Potential as Drug Targets
- (2012) Guoqing Cao et al. Endocrine Metabolic & Immune Disorders-Drug Targets
- Targeting Acyl-CoA:Diacylglycerol Acyltransferase 1 (DGAT1) with Small Molecule Inhibitors for the Treatment of Metabolic Diseases
- (2011) Jingsong Cao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Evidence That Diacylglycerol Acyltransferase 1 (DGAT1) Has Dual Membrane Topology in the Endoplasmic Reticulum of HepG2 Cells
- (2011) Haja R. Wurie et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Murine Diacylglycerol Acyltransferase-2 (DGAT2) Can Catalyze Triacylglycerol Synthesis and Promote Lipid Droplet Formation Independent of Its Localization to the Endoplasmic Reticulum
- (2011) Pamela J. McFie et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Deficiency of MGAT2 increases energy expenditure without high-fat feeding and protects genetically obese mice from excessive weight gain
- (2011) David W. Nelson et al. JOURNAL OF LIPID RESEARCH
- Topological Orientation of Acyl-CoA:Diacylglycerol Acyltransferase-1 (DGAT1) and Identification of a Putative Active Site Histidine and the Role of the N Terminus in Dimer/Tetramer Formation
- (2010) Pamela J. McFie et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Discovery of a Potent, Selective, and Orally Efficacious Pyrimidinooxazinyl Bicyclooctaneacetic Acid Diacylglycerol Acyltransferase-1 Inhibitor
- (2009) Alan M. Birch et al. JOURNAL OF MEDICINAL CHEMISTRY
- Deficiency of the intestinal enzyme acyl CoA:monoacylglycerol acyltransferase-2 protects mice from metabolic disorders induced by high-fat feeding
- (2009) Chi-Liang Eric Yen et al. NATURE MEDICINE
- Discovery of a lysophospholipid acyltransferase family essential for membrane asymmetry and diversity
- (2008) D. Hishikawa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started