Diacylglycerol acyltransferase-1 inhibition enhances intestinal fatty acid oxidation and reduces energy intake in rats

Intestinal DGAT1 deficiency reduces postprandial triglyceride and retinyl ester excursions by inhibiting chylomicron secretion and delaying gastric emptying

(2012) Gene P. Ables et al.   JOURNAL OF LIPID RESEARCH

Vagal Afferents Mediate Early Satiation and Prevent Flavour Avoidance Learning in Response to Intraperitoneally Infused Exendin-4

(2012) M. A. Labouesse et al.   JOURNAL OF NEUROENDOCRINOLOGY

MGAT2 deficiency ameliorates high-fat diet-induced obesity and insulin resistance by inhibiting intestinal fat absorption in mice

(2012) Takuma Tsuchida et al.   Lipids in Health and Disease

DGAT-1 inhibition increases plasma glucagon-like peptide-1 (GLP-1) and peptide tyrosine-tyrosine (PYY) levels in response to a high fat (HF) meal in rats

(2011) G. Schober et al.   APPETITE

Discovery of Orally Active Carboxylic Acid Derivatives of 2-Phenyl-5-trifluoromethyloxazole-4-carboxamide as Potent Diacylglycerol Acyltransferase-1 Inhibitors for the Potential Treatment of Obesity and Diabetes

(2011) Yimin Qian et al.   JOURNAL OF MEDICINAL CHEMISTRY

Tracing the fate of dietary fatty acids: metabolic studies of postprandial lipaemia in human subjects

(2011) Barbara Fielding   PROCEEDINGS OF THE NUTRITION SOCIETY

Dietary fat sensing via fatty acid oxidation in enterocytes: possible role in the control of eating

(2010) Wolfgang Langhans et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

In vivo efficacy of acyl CoA: Diacylglycerol acyltransferase (DGAT) 1 inhibition in rodent models of postprandial hyperlipidemia

(2010) Andrew J. King et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Evidence for Physical Association of Mitochondrial Fatty Acid Oxidation and Oxidative Phosphorylation Complexes

(2010) Yudong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intestine-specific expression of acyl CoA:diacylglycerol acyltransferase 1 reverses resistance to diet-induced hepatic steatosis and obesity inDgat1−/−mice

(2010) Bonggi Lee et al.   JOURNAL OF LIPID RESEARCH

Hepatic-Portal Vein Infusions of Glucagon-Like Peptide-1 Reduce Meal Size and Increase c-Fos Expression in the Nucleus Tractus Solitarii, Area Postrema and Central Nucleus of the Amygdala in Rats

(2010) I. Baumgartner et al.   JOURNAL OF NEUROENDOCRINOLOGY

Involvement of nitric oxide in lipopolysaccharide induced anorexia

(2010) Thomas Riediger et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Role of MGAT2 and DGAT1 in the release of gut peptides after triglyceride ingestion

(2009) Mayumi Okawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibitors of diacylglycerol acyltransferase: a review of 2008 patents

(2009) Andrew J King et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Discovery of a Potent, Selective, and Orally Efficacious Pyrimidinooxazinyl Bicyclooctaneacetic Acid Diacylglycerol Acyltransferase-1 Inhibitor

(2009) Alan M. Birch et al.   JOURNAL OF MEDICINAL CHEMISTRY

Beyond triglyceride synthesis: the dynamic functional roles of MGAT and DGAT enzymes in energy metabolism

(2008) Yuguang Shi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice

(2008) Catherine Postic et al.   JOURNAL OF CLINICAL INVESTIGATION

Validation of Diacyl Glycerolacyltransferase I as a Novel Target for the Treatment of Obesity and Dyslipidemia Using a Potent and Selective Small Molecule Inhibitor

(2008) Gang Zhao et al.   JOURNAL OF MEDICINAL CHEMISTRY