The Accessory Factor Nef Links HIV-1 to Tec/Btk Kinases in an Src Homology 3 Domain-dependent Manner
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Title
The Accessory Factor Nef Links HIV-1 to Tec/Btk Kinases in an Src Homology 3 Domain-dependent Manner
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 289, Issue 22, Pages 15718-15728
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2014-04-11
DOI
10.1074/jbc.m114.572099
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Note: Only part of the references are listed.- Effector Kinase Coupling Enables High-Throughput Screens for Direct HIV-1 Nef Antagonists with Antiretroviral Activity
- (2013) Lori A. Emert-Sedlak et al. CHEMISTRY & BIOLOGY
- Activation Loop Dynamics Determine the Different Catalytic Efficiencies of B Cell- and T Cell-Specific Tec Kinases
- (2013) R. E. Joseph et al. Science Signaling
- Nef Alleles from All Major HIV-1 Clades Activate Src-Family Kinases and Enhance HIV-1 Replication in an Inhibitor-Sensitive Manner
- (2012) Purushottam S. Narute et al. PLoS One
- Nef functions in BLT mice to enhance HIV-1 replication and deplete CD4+CD8+ thymocytes
- (2012) Wei Zou et al. Retrovirology
- Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization
- (2012) Gillian M. Schiralli Lester et al. VIROLOGY
- Interactions of the HIV/SIV Pathogenicity Factor Nef with SH3 Domain-Containing Host Cell Proteins
- (2011) Kalle Saksela CURRENT HIV RESEARCH
- The Src, Syk, and Tec family kinases: Distinct types of molecular switches
- (2010) J. Michael Bradshaw CELLULAR SIGNALLING
- Small Molecule Inhibition of HIV-1–Induced MHC-I Down-Regulation Identifies a Temporally Regulated Switch in Nef Action
- (2010) Jimmy D. Dikeakos et al. MOLECULAR BIOLOGY OF THE CELL
- Expression of Nef from unintegrated HIV-1 DNA downregulates cell surface CXCR4 and CCR5 on T-lymphocytes
- (2010) Richard D Sloan et al. Retrovirology
- T-Cell Signaling Regulated by the Tec Family Kinase, Itk
- (2010) A. H. Andreotti et al. Cold Spring Harbor Perspectives in Biology
- Chemical Library Screens Targeting an HIV-1 Accessory Factor/Host Cell Kinase Complex Identify Novel Antiretroviral Compounds
- (2009) Lori Emert-Sedlak et al. ACS Chemical Biology
- Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/Txk
- (2009) Julie A. Readinger et al. IMMUNOLOGICAL REVIEWS
- HIV-1 Nef Dimerization Is Required for Nef-Mediated Receptor Downregulation and Viral Replication
- (2009) Jerrod A. Poe et al. JOURNAL OF MOLECULAR BIOLOGY
- Bimolecular Fluorescence Complementation (BiFC) Analysis as a Probe of Protein Interactions in Living Cells
- (2008) Tom K. Kerppola Annual Review of Biophysics
- Selective targeting of ITK blocks multiple steps of HIV replication
- (2008) J. A. Readinger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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