Non-muscle myosin IIA is involved in focal adhesion and actin remodelling controlling glucose-stimulated insulin secretion

Myosin motor proteins are involved in the final stages of the secretory pathways: Figure 1

(2012) Lisa M. Bond et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure

(2012) Chutima Talchai et al.   CELL

In Vivo Role of Focal Adhesion Kinase in Regulating Pancreatic  -Cell Mass and Function Through Insulin Signaling, Actin Dynamics, and Granule Trafficking

(2012) E. P. Cai et al.   DIABETES

S100P Dissociates Myosin IIA Filaments and Focal Adhesion Sites to Reduce Cell Adhesion and Enhance Cell Migration

(2012) Min Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How focal adhesion kinase achieves regulation by linking ligand binding, localization and action

(2011) Stefan T Arold   CURRENT OPINION IN STRUCTURAL BIOLOGY

Focal Adhesion Remodeling Is Crucial for Glucose-Stimulated Insulin Secretion and Involves Activation of Focal Adhesion Kinase and Paxillin

(2011) D. Rondas et al.   DIABETES

Novel Mechanistic Link between Focal Adhesion Remodeling and Glucose-stimulated Insulin Secretion

(2011) Dieter Rondas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

(2011) Jean-Cheng Kuo et al.   NATURE CELL BIOLOGY

Role for the actomyosin complex in regulated exocytosis revealed by intravital microscopy

(2011) A. Masedunskas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nifedipine Inhibits Vascular Smooth Muscle Cell Dedifferentiation via Downregulation of Akt Signaling

(2010) Taeko Kaimoto et al.   HYPERTENSION

Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation

(2010) Ana M. Pasapera et al.   JOURNAL OF CELL BIOLOGY

The beta cell lesion in type 2 diabetes: there has to be a primary functional abnormality

(2009) S. E. Kahn et al.   DIABETOLOGIA

 - and  -cytoplasmic actins display distinct distribution and functional diversity

(2009) V. Dugina et al.   JOURNAL OF CELL SCIENCE

Myosin 2 Maintains an Open Exocytic Fusion Pore in Secretory Epithelial Cells

(2009) Purnima Bhat et al.   MOLECULAR BIOLOGY OF THE CELL

Non-muscle myosin II takes centre stage in cell adhesion and migration

(2009) Miguel Vicente-Manzanares et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Role of the Rho-ROCK (Rho-Associated Kinase) Signaling Pathway in the Regulation of Pancreatic β-Cell Function

(2008) Eva Hammar et al.   ENDOCRINOLOGY