Structure of theToxoplasma gondiiROP18 Kinase Domain Reveals a Second Ligand Binding Pocket Required for Acute Virulence

Guanylate-binding Protein 1 (Gbp1) Contributes to Cell-autonomous Immunity against Toxoplasma gondii

(2013) Elizabeth M. Selleck et al.   PLoS Pathogens

The arginine-rich N-terminal domain of ROP18 is necessary for vacuole targeting and virulence ofToxoplasma gondii

(2012) Sarah J. Fentress et al.   CELLULAR MICROBIOLOGY

A Cluster of Interferon-γ-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondii

(2012) Masahiro Yamamoto et al.   IMMUNITY

Murine Guanylate Binding Protein 2 (mGBP2) controls Toxoplasma gondii replication

(2012) D. Degrandi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Rhoptry Proteins ROP18 and ROP5 Mediate Toxoplasma gondii Evasion of the Murine, But Not the Human, Interferon-Gamma Response

(2012) Wendy Niedelman et al.   PLoS Pathogens

The Phosphoproteomes of Plasmodium falciparum and Toxoplasma gondii Reveal Unusual Adaptations Within and Beyond the Parasites' Boundaries

(2011) Moritz Treeck et al.   Cell Host & Microbe

The IRG protein-based resistance mechanism in mice and its relation to virulence in Toxoplasma gondii

(2011) Jonathan C Howard et al.   CURRENT OPINION IN MICROBIOLOGY

Toxoplasma and Plasmodium protein kinases: Roles in invasion and host cell remodelling

(2011) Daniel C. Lim et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

A Conserved Non-canonical Motif in the Pseudoactive Site of the ROP5 Pseudokinase Domain Mediates Its Effect on Toxoplasma Virulence

(2011) Michael L. Reese et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATF6β is a host cellular target of theToxoplasma gondiivirulence factor ROP18

(2011) Masahiro Yamamoto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Strain-specific activation of the NF-κB pathway by GRA15, a novelToxoplasma gondiidense granule protein

(2011) Emily E. Rosowski et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Analysis of the glycoproteome of Toxoplasma gondii using lectin affinity chromatography and tandem mass spectrometry

(2011) Qilie Luo et al.   MICROBES AND INFECTION

Spatial Exclusivity Combined with Positive and Negative Selection of Phosphorylation Motifs Is the Basis for Context-Dependent Mitotic Signaling

(2011) J. Alexander et al.   Science Signaling

Toxoplasma gondii effectors are master regulators of the inflammatory response

(2011) Mariane B. Melo et al.   TRENDS IN PARASITOLOGY

Quantitative in vivo Analyses Reveal Calcium-dependent Phosphorylation Sites and Identifies a Novel Component of the Toxoplasma Invasion Motor Complex

(2011) Thomas Nebl et al.   PLoS Pathogens

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Integrative Genomic Approaches Highlight a Family of Parasite-Specific Kinases that Regulate Host Responses

(2010) Lucia Peixoto et al.   Cell Host & Microbe

Phosphorylation of Immunity-Related GTPases by a Toxoplasma gondii-Secreted Kinase Promotes Macrophage Survival and Virulence

(2010) Sarah J. Fentress et al.   Cell Host & Microbe

Phosphorylation of Mouse Immunity-Related GTPase (IRG) Resistance Proteins Is an Evasion Strategy for Virulent Toxoplasma gondii

(2010) Tobias Steinfeldt et al.   PLOS BIOLOGY

Novel structural and regulatory features of rhoptry secretory kinases in Toxoplasma gondii

(2009) Wei Qiu et al.   EMBO JOURNAL

First Inactive Conformation of CK2α, the Catalytic Subunit of Protein Kinase CK2

(2009) Jennifer Raaf et al.   JOURNAL OF MOLECULAR BIOLOGY

ROP2 from Toxoplasma gondii: A Virulence Factor with a Protein-Kinase Fold and No Enzymatic Activity

(2009) Gilles Labesse et al.   STRUCTURE

A Helical Membrane-Binding Domain Targets theToxoplasmaROP2 Family to the Parasitophorous Vacuole

(2009) Michael L. Reese et al.   TRAFFIC

Population Structure ofToxoplasma gondii: Clonal Expansion Driven by Infrequent Recombination and Selective Sweeps

(2008) L. David Sibley et al.   Annual Review of Microbiology

The CK2α/CK2β Interface of Human Protein Kinase CK2 Harbors a Binding Pocket for Small Molecules

(2008) Jennifer Raaf et al.   CHEMISTRY & BIOLOGY

Toxoplasma gondii infection in humans and animals in the United States

(2008) J DUBEY et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

XtalView, protein structure solution and protein graphics, a short history

(2008) Duncan E. McRee et al.   JOURNAL OF STRUCTURAL BIOLOGY

Identification of chemical inhibitors of protein-kinase CK2 subunit interaction

(2008) Béatrice Laudet et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Kiss and spit: the dual roles of Toxoplasma rhoptries

(2007) John C. Boothroyd et al.   NATURE REVIEWS MICROBIOLOGY