Structure and Function of Hainantoxin-III, a Selective Antagonist of Neuronal Tetrodotoxin-sensitive Voltage-gated Sodium Channels Isolated from the Chinese Bird SpiderOrnithoctonus hainana

Sequence-specific 1H-NMR Assignment and Determination of the Secondary Structure of Hainantoxin-III from the Spider Ornithoctonus hainana

(2013) Zhonghua Liu et al.   PROTEIN AND PEPTIDE LETTERS

Mapping the Interaction Site for a β-Scorpion Toxin in the Pore Module of Domain III of Voltage-gated Na+Channels

(2012) Joel Z. Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A positively charged surface patch is important for hainantoxin-IV binding to voltage-gated sodium channels

(2012) Yu Liu et al.   JOURNAL OF PEPTIDE SCIENCE

Voltage-gated sodium channels at 60: structure, function and pathophysiology

(2012) William A. Catterall   JOURNAL OF PHYSIOLOGY-LONDON

Venoms as a platform for human drugs: translating toxins into therapeutics

(2011) Glenn F King   EXPERT OPINION ON BIOLOGICAL THERAPY

Common Molecular Determinants of Tarantula Huwentoxin-IV Inhibition of Na+Channel Voltage Sensors in Domains II and IV

(2011) Yucheng Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure-Function Map of the Receptor Site for β-Scorpion Toxins in Domain II of Voltage-gated Sodium Channels

(2011) Joel Z. Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NaV  Subunits Modulate the Inhibition of NaV1.8 by the Analgesic Gating Modifier  O-Conotoxin MrVIB

(2011) M. J. Wilson et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Are Voltage-Gated Sodium Channels on the Dorsal Root Ganglion Involved in the Development of Neuropathic Pain?

(2011) Wei Wang et al.   Molecular Pain

The effects of huwentoxin-I on the voltage-gated sodium channels of rat hippocampal and cockroach dorsal unpaired median neurons

(2011) Meichi Wang et al.   PEPTIDES

Mapping the receptor site for  -scorpion toxins on a Na+ channel voltage sensor

(2011) J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

 -Conotoxins that differentially block sodium channels NaV1.1 through 1.8 identify those responsible for action potentials in sciatic nerve

(2011) M. J. Wilson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurotoxins and Their Binding Areas on Voltage-Gated Sodium Channels

(2011) Marijke Stevens et al.   Frontiers in Pharmacology

Sodium Channels in Normal and Pathological Pain

(2010) Sulayman D. Dib-Hajj et al.   Annual Review of Neuroscience

Interaction between voltage-gated sodium channels and the neurotoxin, tetrodotoxin

(2010) Chong Hyun Lee et al.   Channels

Unique Bell-shaped Voltage-dependent Modulation of Na+Channel Gating by Novel Insect-selective Toxins from the SpiderAgelena orientalis

(2010) Bert Billen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nociceptors: the sensors of the pain pathway

(2010) Adrienne E. Dubin et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular Diversification of Peptide Toxins from the TarantulaHaplopelma hainanum(Ornithoctonus hainana) Venom Based on Transcriptomic, Peptidomic, and Genomic Analyses

(2010) Xing Tang et al.   JOURNAL OF PROTEOME RESEARCH

The Tarantula Toxins ProTx-II and Huwentoxin-IV Differentially Interact with Human Nav1.7 Voltage Sensors to Inhibit Channel Activation and Inactivation

(2010) Y. Xiao et al.   MOLECULAR PHARMACOLOGY

ATDB 2.0: A database integrated toxin-ion channel interaction data

(2010) Quanze He et al.   TOXICON

Targeting voltage sensors in sodium channels with spider toxins

(2010) Frank Bosmans et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Venomics as a drug discovery platform

(2009) Pierre Escoubas et al.   Expert Review of Proteomics

Molecular Requirements for Recognition of Brain Voltage-gated Sodium Channels by Scorpion α-Toxins

(2009) Roy Kahn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthesis, Solution Structure, and Phylum Selectivity of a Spider δ-Toxin That Slows Inactivation of Specific Voltage-gated Sodium Channel Subtypes

(2009) Nahoko Yamaji et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Voltage-Gated Sodium Channels: Therapeutic Targets for Pain

(2009) Sulayman D. Dib-Hajj et al.   PAIN MEDICINE

Animal Peptides Targeting Voltage-Activated Sodium Channels

(2008) Bert Billen et al.   CURRENT PHARMACEUTICAL DESIGN

Tarantula Huwentoxin-IV Inhibits Neuronal Sodium Channels by Binding to Receptor Site 4 and Trapping the Domain II Voltage Sensor in the Closed Configuration

(2008) Yucheng Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY