Role of ATRX in chromatin structure and function: implications for chromosome instability and human disease

Escape from X inactivation in mice and humans

(2012) Joel B Berletch et al.   GENOME BIOLOGY

Defective survival of proliferating Sertoli cells and androgen receptor function in a mouse model of the ATR-X syndrome

(2011) Stefan Bagheri-Fam et al.   HUMAN MOLECULAR GENETICS

The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9

(2011) Arunkumar Dhayalan et al.   HUMAN MOLECULAR GENETICS

Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development

(2011) Ikuhiro Okamoto et al.   NATURE

New Epigenetic Drivers of Cancers

(2011) S. J. Elsasser et al.   SCIENCE

DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors

(2011) Y. Jiao et al.   SCIENCE

Identification of regulatory elements flanking human XIST reveals species differences

(2010) Samuel C Chang et al.   BMC MOLECULAR BIOLOGY

Derivation of Pre-X Inactivation Human Embryonic Stem Cells under Physiological Oxygen Concentrations

(2010) Christopher J. Lengner et al.   CELL

Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions

(2010) Aaron D. Goldberg et al.   CELL

ATR-X Syndrome Protein Targets Tandem Repeats and Influences Allele-Specific Expression in a Size-Dependent Manner

(2010) Martin J. Law et al.   CELL

LINE-1 Activity in Facultative Heterochromatin Formation during X Chromosome Inactivation

(2010) Jennifer C. Chow et al.   CELL

The Trithorax group protein Ash2l and Saf-A are recruited to the inactive X chromosome at the onset of stable X inactivation

(2010) D. Pullirsch et al.   DEVELOPMENT

Histone Variants in Metazoan Development

(2010) Laura A. Banaszynski et al.   DEVELOPMENTAL CELL

ATRX Partners with Cohesin and MeCP2 and Contributes to Developmental Silencing of Imprinted Genes in the Brain

(2010) Kristin D. Kernohan et al.   DEVELOPMENTAL CELL

X-changing information on X inactivation

(2010) Tahsin Stefan Barakat et al.   EXPERIMENTAL CELL RESEARCH

The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3

(2010) P. Drane et al.   GENES & DEVELOPMENT

ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells

(2010) L. H. Wong et al.   GENOME RESEARCH

Ring1B Compacts Chromatin Structure and Represses Gene Expression Independent of Histone Ubiquitination

(2010) Ragnhild Eskeland et al.   MOLECULAR CELL

Analysis of Active and Inactive X Chromosome Architecture Reveals the Independent Organization of 30 nm and Large-Scale Chromatin Structures

(2010) Catherine Naughton et al.   MOLECULAR CELL

Epigenetic modifications on X chromosomes in marsupial and monotreme mammals and implications for evolution of dosage compensation

(2010) Willem Rens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres

(2010) P. W. Lewis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-Resolution Analysis of Parent-of-Origin Allelic Expression in the Mouse Brain

(2010) C. Gregg et al.   SCIENCE

Sex-Specific Parent-of-Origin Allelic Expression in the Mouse Brain

(2010) C. Gregg et al.   SCIENCE

Histone variant macroH2A1 deletion in mice causes female-specific steatosis

(2010) Mathieu Boulard et al.   Epigenetics & Chromatin

Loss of Maternal ATRX Results in Centromere Instability and Aneuploidy in the Mammalian Oocyte and Pre-Implantation Embryo

(2010) Claudia Baumann et al.   PLoS Genetics

RNF12 Is an X-Encoded Dose-Dependent Activator of X Chromosome Inactivation

(2009) Iris Jonkers et al.   CELL

Unravelling the evolutionary origins of X chromosome inactivation in mammals: insights from marsupials and monotremes

(2009) Janine E. Deakin et al.   CHROMOSOME RESEARCH

Lessons from comparative analysis of X-chromosome inactivation in mammals

(2009) Ikuhiro Okamoto et al.   CHROMOSOME RESEARCH

Key Features of the X Inactivation Process Are Conserved between Marsupials and Eutherians

(2009) Shantha K. Mahadevaiah et al.   CURRENT BIOLOGY

Persistence of histone H2AX phosphorylation after meiotic chromosome synapsis and abnormal centromere cohesion in poly (ADP-ribose) polymerase (Parp-1) null oocytes

(2009) Feikun Yang et al.   DEVELOPMENTAL BIOLOGY

SATB1 Defines the Developmental Context for Gene Silencing by Xist in Lymphoma and Embryonic Cells

(2009) Ruben Agrelo et al.   DEVELOPMENTAL CELL

The long and the short of it: RNA-directed chromatin asymmetry in mammalian X-chromosome inactivation

(2009) Chandrasekhar Kanduri et al.   FEBS LETTERS

Lessons from X-chromosome inactivation: long ncRNA as guides and tethers to the epigenome

(2009) J. T. Lee   GENES & DEVELOPMENT

High-resolution analysis of epigenetic changes associated with X inactivation

(2009) H. Marks et al.   GENOME RESEARCH

AURKB-mediated effects on chromatin regulate binding versus release of XIST RNA to the inactive chromosome

(2009) Lisa L. Hall et al.   JOURNAL OF CELL BIOLOGY

Assessment of ATRX expression in patients with myelodysplastic syndromes treated with decitabine

(2009) David P. Steensma et al.   LEUKEMIA RESEARCH

A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation

(2009) Gyula Timinszky et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Histone macroH2A isoforms predict the risk of lung cancer recurrence

(2009) J C Sporn et al.   ONCOGENE

Dynamic changes in paternal X-chromosome activity during imprinted X-chromosome inactivation in mice

(2009) C. Patrat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

X Chromosome Dosage Compensation: How Mammals Keep the Balance

(2008) Bernhard Payer et al.   Annual Review of Genetics

Association of ATRX with pericentric heterochromatin and the Y chromosome of neonatal mouse spermatogonia

(2008) Claudia Baumann et al.   BMC MOLECULAR BIOLOGY

The role of X-inactivation in the gender bias of patients with acquired α-thalassaemia and myelodysplastic syndrome (ATMDS)

(2008) Peter S. Haas et al.   BRITISH JOURNAL OF HAEMATOLOGY

ATRX marks the inactive X chromosome (Xi) in somatic cells and during imprinted X chromosome inactivation in trophoblast stem cells

(2008) Claudia Baumann et al.   CHROMOSOMA

Mutations in the chromatin-associated protein ATRX

(2008) Richard J. Gibbons et al.   HUMAN MUTATION

Loss of ATRX leads to chromosome cohesion and congression defects

(2008) Kieran Ritchie et al.   JOURNAL OF CELL BIOLOGY

X-inactivation reveals epigenetic anomalies in most hESC but identifies sublines that initiate as expected

(2008) Lisa L. Hall et al.   JOURNAL OF CELLULAR PHYSIOLOGY

X-Chromosome Inactivation and Skin Disease

(2008) Bryan K. Sun et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

X Inactivation, Female Mosaicism, and Sex Differences in Renal Diseases

(2008) B. R. Migeon   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Kcnq1ot1 Antisense Noncoding RNA Mediates Lineage-Specific Transcriptional Silencing through Chromatin-Level Regulation

(2008) Radha Raman Pandey et al.   MOLECULAR CELL

PHD fingers in human diseases: Disorders arising from misinterpreting epigenetic marks

(2008) Lindsey A. Baker et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation

(2008) Marnie E Blewitt et al.   NATURE GENETICS

X-chromosome inactivation and epigenetic fluidity in human embryonic stem cells

(2008) S. S. Silva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Coupling of Xist Regulation and Pluripotency

(2008) P. Navarro et al.   SCIENCE

Epigenetic regulation and the pathogenesis of systemic lupus erythematosus

(2008) Yujun Pan et al.   Translational Research